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Aliases for C3orf80 Gene

Aliases for C3orf80 Gene

  • Chromosome 3 Open Reading Frame 80 2 3 5

External Ids for C3orf80 Gene

Previous GeneCards Identifiers for C3orf80 Gene

  • GC03P159945

Summaries for C3orf80 Gene

GeneCards Summary for C3orf80 Gene

C3orf80 (Chromosome 3 Open Reading Frame 80) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf80 Gene

Genomics for C3orf80 Gene

Regulatory Elements for C3orf80 Gene

Promoters for C3orf80 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C3orf80 on UCSC Golden Path with GeneCards custom track

Genomic Location for C3orf80 Gene

Chromosome:
3
Start:
160,223,784 bp from pter
End:
160,290,143 bp from pter
Size:
66,360 bases
Orientation:
Plus strand

Genomic View for C3orf80 Gene

Genes around C3orf80 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C3orf80 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C3orf80 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf80 Gene

Proteins for C3orf80 Gene

  • Protein details for C3orf80 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    F5H4A9-CC080_HUMAN
    Recommended name:
    Uncharacterized membrane protein C3orf80
    Protein Accession:
    F5H4A9
    Secondary Accessions:
    • Q8N5S4

    Protein attributes for C3orf80 Gene

    Size:
    247 amino acids
    Molecular mass:
    25682 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C3orf80 Gene

Proteomics data for C3orf80 Gene at MOPED

Post-translational modifications for C3orf80 Gene

  • Glycosylation at Asn 57
  • Modification sites at PhosphoSitePlus

Other Protein References for C3orf80 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C3orf80 Gene

Domains & Families for C3orf80 Gene

Protein Domains for C3orf80 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf80: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf80 Gene

Function for C3orf80 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C3orf80 Gene

Localization for C3orf80 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C3orf80 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C3orf80 Gene COMPARTMENTS Subcellular localization image for C3orf80 gene
Compartment Confidence
extracellular 3
endoplasmic reticulum 1

No data available for Gene Ontology (GO) - Cellular Components for C3orf80 Gene

Pathways & Interactions for C3orf80 Gene

SuperPathways for C3orf80 Gene

No Data Available

Interacting Proteins for C3orf80 Gene

Gene Ontology (GO) - Biological Process for C3orf80 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C3orf80 Gene

Drugs & Compounds for C3orf80 Gene

No Compound Related Data Available

Transcripts for C3orf80 Gene

mRNA/cDNA for C3orf80 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(16) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C3orf80 Gene

Chromosome 3 open reading frame 80:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf80 Gene

No ASD Table

Relevant External Links for C3orf80 Gene

GeneLoc Exon Structure for
C3orf80
ECgene alternative splicing isoforms for
C3orf80

Expression for C3orf80 Gene

mRNA expression in normal human tissues for C3orf80 Gene

mRNA expression in normal human tissues for C3orf80 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C3orf80 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C3orf80 Gene



SOURCE GeneReport for Unigene cluster for C3orf80 Gene Hs.729755

genes like me logo Genes that share expression patterns with C3orf80: view

Protein tissue co-expression partners for C3orf80 Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C3orf80 Gene

Orthologs for C3orf80 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C3orf80 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C3H3orf80 35
  • 99.46 (n)
  • 100 (a)
C3orf80 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C3orf80 36
  • 91 (a)
OneToOne
C1H3orf80 35
  • 87.98 (n)
  • 88.11 (a)
dog
(Canis familiaris)
Mammalia C3orf80 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1110032F04Rik 16
1110032F04Rik 36
  • 91 (a)
OneToOne
1110032F04Rik 35
  • 86.99 (n)
  • 88.62 (a)
oppossum
(Monodelphis domestica)
Mammalia C3orf80 36
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100362176 35
  • 86.99 (n)
  • 89.02 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100496145 35
  • 68.95 (n)
  • 68.49 (a)
Species with no ortholog for C3orf80:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf80 Gene

ENSEMBL:
Gene Tree for C3orf80 (if available)
TreeFam:
Gene Tree for C3orf80 (if available)

Paralogs for C3orf80 Gene

No data available for Paralogs for C3orf80 Gene

Variants for C3orf80 Gene

Sequence variations from dbSNP and Humsavar for C3orf80 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs2152426 -- 160,224,658(+) CTTAG(A/G)CATTT nc-transcript-variant, upstream-variant-2KB
rs2366819 -- 160,242,370(+) aacaa(G/T)tacta intron-variant
rs2275149 -- 160,226,527(+) GTCTC(C/T)CTCGC nc-transcript-variant, utr-variant-3-prime
rs4532176 -- 160,255,315(+) gtcat(A/G)tggtc intron-variant
rs4680571 -- 160,227,422(+) AATAT(A/T)TAACT intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C3orf80 Gene

Variant ID Type Subtype PubMed ID
nsv877699 CNV Gain 21882294

Variation tolerance for C3orf80 Gene

Gene Damage Index Score: 1.89; 35.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C3orf80 Gene

HapMap Linkage Disequilibrium report
C3orf80

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf80 Gene

Disorders for C3orf80 Gene

Relevant External Links for C3orf80

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C3orf80

No disorders were found for C3orf80 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf80 Gene

Publications for C3orf80 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for C3orf80 Gene

Sources for C3orf80 Gene

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