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Aliases for C3orf80 Gene

Aliases for C3orf80 Gene

  • Chromosome 3 Open Reading Frame 80 2 3 5

External Ids for C3orf80 Gene

Previous GeneCards Identifiers for C3orf80 Gene

  • GC03P159945

Summaries for C3orf80 Gene

GeneCards Summary for C3orf80 Gene

C3orf80 (Chromosome 3 Open Reading Frame 80) is a Protein Coding gene.

Additional gene information for C3orf80 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf80 Gene

Genomics for C3orf80 Gene

Regulatory Elements for C3orf80 Gene

Enhancers for C3orf80 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03H160168 0.9 Ensembl ENCODE 12.8 -54.5 -54458 1 MAFG FOSL1 ZNF316 JUND IKZF1 NFE2 FOS MAFK EMSY NFE2L2 C3orf80 IL12A-AS1 BRD7P2
GH03H159897 0.9 ENCODE dbSUPER 10 -325.6 -325638 1 FEZF1 ZNF518A ATF2 NR2F2 OSR2 ZFHX2 PRDM6 POLR2A SCRT2 ZNF580 IL12A C3orf80 IL12A-AS1 SCHIP1 LOC101928351
GH03H160413 0.7 ENCODE 10.6 +190.0 190004 0 CTCF ZNF654 FOXA2 FOXA3 TRIM22 ZNF384 REST RAD21 RFX5 FOXA1 B3GAT3P1 IL12A-AS1 C3orf80 IL12A GC03P160413 ENSG00000248710
GH03H159900 0.7 dbSUPER 10 -321.5 -321467 3 PKNOX1 ZSCAN4 BATF HIC1 ZNF366 ATF7 ETV6 IKZF2 CREM NR2F1 IL12A C3orf80 IL12A-AS1 SCHIP1 LOC101928351
GH03H159904 0.5 dbSUPER 10 -318.7 -318727 1 IKZF1 IKZF2 SPI1 IL12A C3orf80 IL12A-AS1 SCHIP1 LOC101928351
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C3orf80 on UCSC Golden Path with GeneCards custom track

Genomic Location for C3orf80 Gene

Chromosome:
3
Start:
160,223,784 bp from pter
End:
160,290,143 bp from pter
Size:
66,360 bases
Orientation:
Plus strand

Genomic View for C3orf80 Gene

Genes around C3orf80 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C3orf80 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C3orf80 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf80 Gene

Proteins for C3orf80 Gene

  • Protein details for C3orf80 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    F5H4A9-CC080_HUMAN
    Recommended name:
    Uncharacterized membrane protein C3orf80
    Protein Accession:
    F5H4A9
    Secondary Accessions:
    • Q8N5S4

    Protein attributes for C3orf80 Gene

    Size:
    247 amino acids
    Molecular mass:
    25682 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C3orf80 Gene

Post-translational modifications for C3orf80 Gene

  • Glycosylation at Asn57
  • Modification sites at PhosphoSitePlus

Other Protein References for C3orf80 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C3orf80 Gene

Domains & Families for C3orf80 Gene

Gene Families for C3orf80 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for C3orf80 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf80: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf80 Gene

Function for C3orf80 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for C3orf80
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C3orf80 Gene

Localization for C3orf80 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C3orf80 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C3orf80 gene
Compartment Confidence
extracellular 3
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for C3orf80 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C3orf80: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for C3orf80 Gene

Pathways & Interactions for C3orf80 Gene

SuperPathways for C3orf80 Gene

No Data Available

Interacting Proteins for C3orf80 Gene

Gene Ontology (GO) - Biological Process for C3orf80 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C3orf80 Gene

Drugs & Compounds for C3orf80 Gene

No Compound Related Data Available

Transcripts for C3orf80 Gene

mRNA/cDNA for C3orf80 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(16) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C3orf80 Gene

Chromosome 3 open reading frame 80:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for C3orf80
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf80 Gene

No ASD Table

Relevant External Links for C3orf80 Gene

GeneLoc Exon Structure for
C3orf80
ECgene alternative splicing isoforms for
C3orf80

Expression for C3orf80 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C3orf80 Gene

mRNA expression in normal human tissues for C3orf80 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C3orf80 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C3orf80 Gene



Protein tissue co-expression partners for C3orf80 Gene

NURSA nuclear receptor signaling pathways regulating expression of C3orf80 Gene:

C3orf80

SOURCE GeneReport for Unigene cluster for C3orf80 Gene:

Hs.729755

Evidence on tissue expression from TISSUES for C3orf80 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with C3orf80: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C3orf80 Gene

Orthologs for C3orf80 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C3orf80 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C3orf80 34
  • 100 (a)
OneToOne
C3H3orf80 33
  • 99.46 (n)
dog
(Canis familiaris)
Mammalia C3orf80 34
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C3orf80 34
  • 91 (a)
OneToOne
C1H3orf80 33
  • 87.98 (n)
mouse
(Mus musculus)
Mammalia 1110032F04Rik 33 16 34
  • 86.99 (n)
rat
(Rattus norvegicus)
Mammalia LOC100362176 33
  • 86.99 (n)
oppossum
(Monodelphis domestica)
Mammalia C3orf80 34
  • 65 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100496145 33
  • 68.95 (n)
Species where no ortholog for C3orf80 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf80 Gene

ENSEMBL:
Gene Tree for C3orf80 (if available)
TreeFam:
Gene Tree for C3orf80 (if available)

Paralogs for C3orf80 Gene

No data available for Paralogs for C3orf80 Gene

Variants for C3orf80 Gene

Sequence variations from dbSNP and Humsavar for C3orf80 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000138680 -- 160,227,489(+) CACAG(C/T)TATAT utr-variant-3-prime
rs1000564985 -- 160,224,295(+) AGGGG(C/T)CCTCG upstream-variant-2KB
rs1002137719 -- 160,225,470(+) CCTCC(C/G)GCCCA upstream-variant-2KB
rs1002232580 -- 160,225,665(+) GAGGG(C/T)CTGTC reference, synonymous-codon
rs1002462425 -- 160,226,566(+) GTTTC(A/T)TTCCG utr-variant-3-prime

Variation tolerance for C3orf80 Gene

Gene Damage Index Score: 1.89; 35.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C3orf80 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C3orf80

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C3orf80 Gene

Disorders for C3orf80 Gene

Relevant External Links for C3orf80

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C3orf80

No disorders were found for C3orf80 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf80 Gene

Publications for C3orf80 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60
  4. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 60

Products for C3orf80 Gene

Sources for C3orf80 Gene

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