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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C3orf79 Gene

protein-coding   GIFtS: 31
GCID: GC03P153202          (predicted)

Chromosome 3 Open Reading Frame 79

  Search for C3orf79
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Chromosome 3 Open Reading Frame 791 2
Putative Uncharacterized Protein C3orf792

External Ids:    HGNC: 372591   Entrez Gene: 1521182   Ensembl: ENSG000002377877   UniProtKB: P0CE673   

Export aliases for C3orf79 gene to outside databases

Previous GC identifers: GC03P154685 GC03P150594


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for C3orf79 Gene: 
C3orf79 (chromosome 3 open reading frame 79) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_005612.16  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for C3orf79
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for C3orf79

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C3orf79


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.2   Ensembl cytogenetic band:  3q25.2   HGNC cytogenetic band: 3q25.2

C3orf79 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C3orf79 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P153202:  view genomic region     (about GC identifiers)

Start:
153,202,284 bp from pter      End:
153,220,486 bp from pter
Size:
18,203 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CC079_HUMAN, P0CE67 (See protein sequence)
Recommended Name: Putative uncharacterized protein C3orf79  
Size: 100 amino acids; 11337 Da

Explore the universe of human proteins at neXtProt for C3orf79: NX_P0CE67

Explore proteomics data for C3orf79 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P0CE67

  • C3orf79 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    C3orf79 Protein Expression
    REFSEQ proteins: NP_001094807.1  
    ENSEMBL proteins: 
     ENSP00000389475  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: P0CE67


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C3orf79

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C3orf79 (CC079)

    Search CenterWatch for drugs/clinical trials and news about C3orf79 / CC079

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for C3orf79 gene: 
    NM_001101337.1  

    Unigene Cluster for C3orf79:

    Chromosome 3 open reading frame 79
    Hs.58586  [show with all ESTs]
    Unigene Representative Sequence: BG219462
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000446603(uc003ezt.3)
    miRNA
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    Additional mRNA sequence: AF086445.1 

    3 DOTS entries:

    DT.303193  DT.91719047  DT.95200186 

    24/36 AceView cDNA sequences (see all 36):

    BG194487 BX103194 BG209536 W79525 W79557 BG190426 AF086445 BG188256 
    BG184709 BG200129 BG192967 BG196048 BG213671 BG192968 BG217438 BG186111 
    BG216470 BG215297 BG210642 BG184068 BG214760 BG190909 BG190910 BG220455 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C3orf79 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTAATTTC
    C3orf79 Expression
    About this image


    See C3orf79 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C3orf79

    SOURCE GeneReport for Unigene cluster: Hs.58586
        SABiosciences Custom PCR Arrays for C3orf79
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C3orf79

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and chimp.

    Orthologs for C3orf79 gene from 1 species (see representative species )    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chimpanzee
    (Pan troglodytes)
    Mammalia C3H3orf791 chromosome 3 open reading frame, human C3orf79 99.58(n)
    98.73(a)
      739656  XM_001146471.1  XP_001146471.1 


    ENSEMBL Gene Tree for C3orf79 (if available)
    TreeFam Gene Tree for C3orf79 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/415 SNPs in C3orf79 are shown (see all 415)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1830597581,2
    --153200385(+) TATTTC/TTACGG 1 -- us2k10--------
    rs1124059551,2
    C,F--153200393(+) CGGTAT/GAGTCA 1 -- us2k11Minor allele frequency- G:0.00CSA 1
    rs1131433401,2
    C--153200537(+) CCATCG/CTGGCT 1 -- us2k11Minor allele frequency- C:0.50CSA 2
    rs1999759681,2
    C--153200764(-) TTCCTC/TTTTTT 1 -- us2k10--------
    rs802819461,2
    C,F--153200818(+) TCTGAA/TTACAT 1 -- us2k13Minor allele frequency- T:0.07WA NA EA 358
    rs1915821681,2
    --153200851(+) AAGAGC/TTGCGG 1 -- us2k10--------
    rs1828849981,2
    --153200886(+) CATTTA/GCAATG 1 -- us2k10--------
    rs98658051,2
    C--153200904(+) tttgaG/Tttgcc 1 -- us2k110Minor allele frequency- T:0.08NA WA CSA 252
    rs1879288931,2
    --153200983(+) CAGATA/TTACAT 1 -- us2k10--------
    rs1471725311,2
    --153200984(+) AGATAC/TACATT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for C3orf79 (153202284 - 153220486 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for C3orf79:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2677975CNV Deletion23128226
    nsv526058CNV Loss19592680
    nsv460913CNV Gain19166990

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    C3orf79 for disorders           About MalaCards

    C3orf79 for disorders           About GeneDecksing

    Genetic Association Database (GAD): C3orf79

    Export disorders for C3orf79 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C3orf79 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with C3orf79)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Common variants near MBNL1 and NKX2-5 are associated w ith infantile hypertrophic pyloric stenosis. (PubMed id 22306654)4 Feenstra B....Melbye M. (2012)
    2. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (2007)
    3. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (2006)
    4. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 152118 HGNC: 37259 AceView: LOC152118 Ensembl:ENSG00000237787 euGenes: HUgn152118
    ECgene: C3orf79 H-InvDB: C3orf79

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C3orf79 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C3orf79 gene:
    Search GeneIP for patents involving C3orf79

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    transforming growth factor, beta 1
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