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Aliases for C3orf70 Gene

Aliases for C3orf70 Gene

  • Chromosome 3 Open Reading Frame 70 2 3

External Ids for C3orf70 Gene

Previous GeneCards Identifiers for C3orf70 Gene

  • GC03M186278
  • GC03M184795
  • GC03M182205

Summaries for C3orf70 Gene

GeneCards Summary for C3orf70 Gene

C3orf70 (Chromosome 3 Open Reading Frame 70) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf70 Gene

Genomics for C3orf70 Gene

Regulatory Elements for C3orf70 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C3orf70 Gene

185,078,050 bp from pter
185,153,014 bp from pter
74,965 bases
Minus strand

Genomic View for C3orf70 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C3orf70 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf70 Gene

Proteins for C3orf70 Gene

  • Protein details for C3orf70 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0524 protein C3orf70
    Protein Accession:
    Secondary Accessions:
    • B2RNY2
    • B9EH83

    Protein attributes for C3orf70 Gene

    250 amino acids
    Molecular mass:
    27769 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C3orf70 Gene

Proteomics data for C3orf70 Gene at MOPED

Post-translational modifications for C3orf70 Gene

No Post-translational modifications

Other Protein References for C3orf70 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for C3orf70 Gene

Domains for C3orf70 Gene

Protein Domains for C3orf70 Gene


Suggested Antigen Peptide Sequences for C3orf70 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • A6NLC5
  • Belongs to the UPF0524 family.
genes like me logo Genes that share domains with C3orf70: view

No data available for Gene Families for C3orf70 Gene

Function for C3orf70 Gene

Phenotypes for C3orf70 Gene

GenomeRNAi human phenotypes for C3orf70:
genes like me logo Genes that share phenotypes with C3orf70: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C3orf70

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C3orf70 Gene

Localization for C3orf70 Gene

Subcellular locations from

Jensen Localization Image for C3orf70 Gene COMPARTMENTS Subcellular localization image for C3orf70 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C3orf70 Gene

Pathways for C3orf70 Gene

SuperPathways for C3orf70 Gene

No Data Available

Interacting Proteins for C3orf70 Gene

Gene Ontology (GO) - Biological Process for C3orf70 Gene


No data available for Pathways by source for C3orf70 Gene

Transcripts for C3orf70 Gene

mRNA/cDNA for C3orf70 Gene

(6) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C3orf70 Gene

Chromosome 3 open reading frame 70:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C3orf70

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf70 Gene

No ASD Table

Relevant External Links for C3orf70 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C3orf70 Gene

mRNA expression in normal human tissues for C3orf70 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for C3orf70 Gene Hs.380048

genes like me logo Genes that share expressions with C3orf70: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for C3orf70 Gene

Orthologs for C3orf70 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C3orf70 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C1H3orf70 35
  • 92.93 (n)
  • 96.8 (a)
C3orf70 36
  • 97 (a)
(Canis familiaris)
Mammalia C34H3orf70 35
  • 93.73 (n)
  • 96 (a)
C3orf70 36
  • 96 (a)
(Mus musculus)
Mammalia 2510009E07Rik 35
  • 88.71 (n)
  • 94.76 (a)
2510009E07Rik 16
2510009E07Rik 36
  • 94 (a)
(Pan troglodytes)
Mammalia C3H3orf70 35
  • 99.07 (n)
  • 100 (a)
C3orf70 36
  • 100 (a)
(Rattus norvegicus)
Mammalia RGD1562339 35
  • 89.3 (n)
  • 95.12 (a)
(Monodelphis domestica)
Mammalia C3orf70 36
  • 91 (a)
(Ornithorhynchus anatinus)
Mammalia C3orf70 36
  • 89 (a)
(Gallus gallus)
Aves C9H3orf70 35
  • 78.28 (n)
  • 83.15 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100494388 35
  • 69.83 (n)
  • 73.55 (a)
(Danio rerio)
Actinopterygii si:dkey-22o12.2 35
  • 66.67 (n)
  • 66.95 (a)
C1H3orf70 (2 of 2) 36
  • 58 (a)
C9H3orf70 (1 of 2) 36
  • 61 (a)
Species with no ortholog for C3orf70:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C3orf70 Gene

Gene Tree for C3orf70 (if available)
Gene Tree for C3orf70 (if available)

Paralogs for C3orf70 Gene

No data available for Paralogs for C3orf70 Gene

Variants for C3orf70 Gene

Sequence variations from dbSNP and Humsavar for C3orf70 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs876453 -- 185,081,500(-) AGCGC(A/G)CTCTC utr-variant-3-prime
rs961693 -- 185,133,864(-) tgatc(C/T)gccca intron-variant
rs1016046 -- 185,131,451(+) TATTG(C/T)CTCTT intron-variant
rs1043435 -- 185,079,977(-) ATTAT(A/G)TGAAG utr-variant-3-prime
rs1080471 -- 185,111,435(-) catat(C/T)tattc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C3orf70 Gene

Variant ID Type Subtype PubMed ID
nsv521893 CNV Loss 19592680

Relevant External Links for C3orf70 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf70 Gene

Disorders for C3orf70 Gene

Relevant External Links for C3orf70

Genetic Association Database (GAD)

No disorders were found for C3orf70 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C3orf70 Gene

Publications for C3orf70 Gene

  1. Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. (PMID: 21042317) Wray N.R. … Sullivan P.F. (Mol. Psychiatry 2012) 3 48
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C3orf70 Gene

Sources for C3orf70 Gene

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