Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C3orf62 Gene

Aliases for C3orf62 Gene

  • Chromosome 3 Open Reading Frame 62 2 3 5

External Ids for C3orf62 Gene

Previous GeneCards Identifiers for C3orf62 Gene

  • GC03M049282

Summaries for C3orf62 Gene

GeneCards Summary for C3orf62 Gene

C3orf62 (Chromosome 3 Open Reading Frame 62) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf62 Gene

Genomics for C3orf62 Gene

Regulatory Elements for C3orf62 Gene

Enhancers for C3orf62 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G049338 1.9 FANTOM5 ENCODE dbSUPER 10.9 -68.1 -68141 14.7 MLX CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC AMT QRICH1 IMPDH2 DALRD3 RHOA WDR6 NICN1 USP4 ENSG00000230454 RHOA-IT1
GH03G049409 1.6 Ensembl ENCODE dbSUPER 10.4 -135.9 -135898 8.9 HDGF PKNOX1 FOXA2 ARNT CREB3L1 SIN3A ARID4B DMAP1 YY1 SLC30A9 AMT CCDC71 WDR6 SEMA3F-AS1 QRICH1 FAM212A DAG1 RNA5SP130 TMEM115 USP4
GH03G049248 1.4 FANTOM5 Ensembl ENCODE 11.7 +29.0 28980 1.5 ATF1 JUN MAX CEBPG ZNF366 EGR1 CREM HLF CEBPB ATF2 AMT WDR6 USP4 C3orf62 LAMB2 KLHDC8B CCDC71 DALRD3 RHOA ARIH2
GH03G049217 1.3 Ensembl ENCODE 11.5 +59.2 59228 2.1 FOXA2 MLX ZNF133 ARID4B DMAP1 ZNF48 GTF3C2 SLC30A9 FOS SP5 AMT WDR6 QRICH1 CCDC71 NME6 MRPS18AP1 ZNF589 SEMA3F-AS1 RHOA-IT1 CCDC36
GH03G049320 1.2 FANTOM5 11.6 -43.2 -43246 0.6 HDGF MLX ARID4B SIN3A DMAP1 FEZF1 ZNF2 YY1 SLC30A9 ZNF143 WDR6 C3orf62 NICN1 AMT LAMB2 CCDC71 KLHDC8B QARS USP4 IP6K1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C3orf62 on UCSC Golden Path with GeneCards custom track

Promoters for C3orf62 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000152201 709 801 BACH1 RAD21 YY1 POLR2A EED IKZF2 CHD2 ZBED1 NR2F1 BHLHE40

Genomic Location for C3orf62 Gene

Chromosome:
3
Start:
49,268,597 bp from pter
End:
49,277,909 bp from pter
Size:
9,313 bases
Orientation:
Minus strand

Genomic View for C3orf62 Gene

Genes around C3orf62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C3orf62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C3orf62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf62 Gene

Proteins for C3orf62 Gene

  • Protein details for C3orf62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZUJ4-CC062_HUMAN
    Recommended name:
    Uncharacterized protein C3orf62
    Protein Accession:
    Q6ZUJ4
    Secondary Accessions:
    • Q6P7E9
    • Q7Z3X6

    Protein attributes for C3orf62 Gene

    Size:
    267 amino acids
    Molecular mass:
    30194 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C3orf62 Gene

Post-translational modifications for C3orf62 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C3orf62 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C3orf62 Gene

Domains & Families for C3orf62 Gene

Protein Domains for C3orf62 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf62: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf62 Gene

Function for C3orf62 Gene

Gene Ontology (GO) - Molecular Function for C3orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C3orf62: view

Phenotypes for C3orf62 Gene

genes like me logo Genes that share phenotypes with C3orf62: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C3orf62 Gene

Localization for C3orf62 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C3orf62 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1
mitochondrion 1
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C3orf62 Gene

Pathways & Interactions for C3orf62 Gene

SuperPathways for C3orf62 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C3orf62 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C3orf62 Gene

Transcripts for C3orf62 Gene

Unigene Clusters for C3orf62 Gene

Chromosome 3 open reading frame 62:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf62 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c
SP1: -
SP2:
SP3: -

Relevant External Links for C3orf62 Gene

GeneLoc Exon Structure for
C3orf62
ECgene alternative splicing isoforms for
C3orf62

Expression for C3orf62 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C3orf62 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C3orf62 Gene

This gene is overexpressed in Whole Blood (x8.3).

NURSA nuclear receptor signaling pathways regulating expression of C3orf62 Gene:

C3orf62

SOURCE GeneReport for Unigene cluster for C3orf62 Gene:

Hs.403828
genes like me logo Genes that share expression patterns with C3orf62: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C3orf62 Gene

Orthologs for C3orf62 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C3orf62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C3H3orf62 34 35
  • 99.13 (n)
dog
(Canis familiaris)
Mammalia C20H3orf62 34
  • 86.02 (n)
C3orf62 35
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700102P08Rik 34 16 35
  • 84.86 (n)
cow
(Bos Taurus)
Mammalia C22H3orf62 34
  • 84.44 (n)
C3orf62 35
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC498675 34
  • 83.67 (n)
oppossum
(Monodelphis domestica)
Mammalia C3orf62 35
  • 66 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C3orf62 35
  • 31 (a)
OneToOne
Species where no ortholog for C3orf62 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf62 Gene

ENSEMBL:
Gene Tree for C3orf62 (if available)
TreeFam:
Gene Tree for C3orf62 (if available)

Paralogs for C3orf62 Gene

No data available for Paralogs for C3orf62 Gene

Variants for C3orf62 Gene

Sequence variations from dbSNP and Humsavar for C3orf62 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000050116 -- 49,275,429(+) GGAGT(G/T)GAAAG intron-variant
rs1000222645 -- 49,275,693(+) GCCCG(A/G)CTAAT intron-variant
rs1000272501 -- 49,268,174(+) CAAGC(C/T)CTCCT downstream-variant-500B
rs1000403796 -- 49,275,720(+) GAGAC(-/A)AGAGT intron-variant
rs1000759051 -- 49,274,555(+) AGTCT(C/T)GCTTT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for C3orf62 Gene

Variant ID Type Subtype PubMed ID
nsv1008750 CNV gain 25217958

Variation tolerance for C3orf62 Gene

Residual Variation Intolerance Score: 65.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.64; 65.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C3orf62 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C3orf62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf62 Gene

Disorders for C3orf62 Gene

Relevant External Links for C3orf62

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C3orf62

No disorders were found for C3orf62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf62 Gene

Publications for C3orf62 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3 64

Products for C3orf62 Gene

Sources for C3orf62 Gene

Content
Loading form....