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Aliases for C3orf56 Gene

Aliases for C3orf56 Gene

  • Chromosome 3 Open Reading Frame 56 2 3 5

External Ids for C3orf56 Gene

Previous GeneCards Identifiers for C3orf56 Gene

  • GC03P128396
  • GC03P126911
  • GC03P124290

Summaries for C3orf56 Gene

GeneCards Summary for C3orf56 Gene

C3orf56 (Chromosome 3 Open Reading Frame 56) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf56 Gene

Genomics for C3orf56 Gene

Regulatory Elements for C3orf56 Gene

Enhancers for C3orf56 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F127172 1 Ensembl ENCODE 0.3 -20.0 -20031 1.0 JUN SIN3A RAD21 HIC1 GLIS2 ZNF600 FOS NFE2 ZBTB20 TCF7L2 C3orf56 GC03M127051 PIR34743
GH03F127158 0.7 ENCODE 0.3 -33.8 -33818 1.7 RFX1 HCFC1 MIER1 SIN3A MNT MIER2 REST SMARCA4 POLR2A ZNF585B RNU6-1047P C3orf56 GC03M127051 PIR34743
GH03F127113 0.8 ENCODE 0.2 -79.9 -79930 0.1 SOX13 CEBPG E2F1 GATA3 CTBP1 RERE RCOR1 FOSL2 FOS EZH2 PIR34743 GC03M127051 C3orf56
GH03F127135 0.8 FANTOM5 0.2 -57.6 -57563 0.4 MAZ SUZ12 KLF17 ZBTB8A ZIC2 ZFHX2 GLIS2 ZBTB48 PATZ1 GLIS1 TXNRD3 C3orf56 PIR34743 GC03M127051
GH03F127141 0.7 ENCODE 0.2 -50.9 -50948 1.0 TFAP4 STAT1 NFIA CEBPB REST FEZF1 HHEX GATA3 RERE BCL6 C3orf56 GC03M127051 PIR34743
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C3orf56 on UCSC Golden Path with GeneCards custom track

Genomic Location for C3orf56 Gene

Chromosome:
3
Start:
127,193,131 bp from pter
End:
127,198,185 bp from pter
Size:
5,055 bases
Orientation:
Plus strand

Genomic View for C3orf56 Gene

Genes around C3orf56 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C3orf56 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C3orf56 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf56 Gene

Proteins for C3orf56 Gene

  • Protein details for C3orf56 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N813-CC056_HUMAN
    Recommended name:
    Putative uncharacterized protein C3orf56
    Protein Accession:
    Q8N813
    Secondary Accessions:
    • B2RNW5

    Protein attributes for C3orf56 Gene

    Size:
    242 amino acids
    Molecular mass:
    26007 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C3orf56 Gene

Post-translational modifications for C3orf56 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C3orf56 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C3orf56 Gene

Domains & Families for C3orf56 Gene

Protein Domains for C3orf56 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf56: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf56 Gene

Function for C3orf56 Gene

genes like me logo Genes that share phenotypes with C3orf56: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C3orf56 Gene

Localization for C3orf56 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C3orf56 gene
Compartment Confidence
peroxisome 2
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C3orf56 Gene

Pathways & Interactions for C3orf56 Gene

SuperPathways for C3orf56 Gene

No Data Available

Interacting Proteins for C3orf56 Gene

Gene Ontology (GO) - Biological Process for C3orf56 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C3orf56 Gene

Transcripts for C3orf56 Gene

mRNA/cDNA for C3orf56 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C3orf56 Gene

Chromosome 3 open reading frame 56:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf56 Gene

No ASD Table

Relevant External Links for C3orf56 Gene

GeneLoc Exon Structure for
C3orf56
ECgene alternative splicing isoforms for
C3orf56

Expression for C3orf56 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C3orf56 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C3orf56 Gene

This gene is overexpressed in Testis (x38.2).

Protein differential expression in normal tissues from HIPED for C3orf56 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C3orf56 Gene



Protein tissue co-expression partners for C3orf56 Gene

NURSA nuclear receptor signaling pathways regulating expression of C3orf56 Gene:

C3orf56

SOURCE GeneReport for Unigene cluster for C3orf56 Gene:

Hs.591284
genes like me logo Genes that share expression patterns with C3orf56: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for C3orf56 Gene

Orthologs for C3orf56 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C3orf56 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC736473 34
  • 98.76 (n)
C3orf56 35
  • 98 (a)
OneToOne
Species where no ortholog for C3orf56 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf56 Gene

ENSEMBL:
Gene Tree for C3orf56 (if available)
TreeFam:
Gene Tree for C3orf56 (if available)

Paralogs for C3orf56 Gene

No data available for Paralogs for C3orf56 Gene

Variants for C3orf56 Gene

Sequence variations from dbSNP and Humsavar for C3orf56 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs10623171 -- 127,197,590(+) TTACT(-/TTC)TTGTT utr-variant-3-prime
rs111607955 -- 127,197,596(+) TTGTT(G/T)TTCTG utr-variant-3-prime
rs112289272 -- 127,191,878(+) TCCAC(C/T)GCACT upstream-variant-2KB
rs112772316 -- 127,195,175(+) CCCAC(A/G)CACAC intron-variant
rs113513722 -- 127,195,833(+) TGTAC(A/T)GCGCA intron-variant

Variation tolerance for C3orf56 Gene

Residual Variation Intolerance Score: 82.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.76; 15.95% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C3orf56 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C3orf56

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C3orf56 Gene

Disorders for C3orf56 Gene

Relevant External Links for C3orf56

Genetic Association Database (GAD)
C3orf56
Human Genome Epidemiology (HuGE) Navigator
C3orf56
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C3orf56

No disorders were found for C3orf56 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf56 Gene

Publications for C3orf56 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4 64
  2. Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. (PMID: 24529757) Xie T. … Xu R. (Neurobiol. Aging 2014) 3 64
  3. A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. (PMID: 24025145) Chung S. … Nakamura Y. (Breast Cancer Res. 2013) 3 64
  4. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. (PMID: 21116278) Furney S.J. … . (Mol. Psychiatry 2011) 46 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for C3orf56 Gene

Sources for C3orf56 Gene

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