Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C3orf52 Gene

Aliases for C3orf52 Gene

  • Chromosome 3 Open Reading Frame 52 2 3
  • TTMP 3 4 6
  • TPA Induced Trans-Membrane Protein 2 3
  • Novel Endoplasmic Reticulum Transmembrane Protein 3
  • TPA-Induced Transmembrane Protein 3

External Ids for C3orf52 Gene

Summaries for C3orf52 Gene

GeneCards Summary for C3orf52 Gene

C3orf52 (Chromosome 3 Open Reading Frame 52) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf52 Gene

Genomics for C3orf52 Gene

Genomic Location for C3orf52 Gene

Start:
112,086,335 bp from pter
End:
112,131,004 bp from pter
Size:
44,670 bases
Orientation:
Plus strand

Genomic View for C3orf52 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C3orf52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf52 Gene

Regulatory Elements for C3orf52 Gene

Proteins for C3orf52 Gene

  • Protein details for C3orf52 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5BVD1-TTMP_HUMAN
    Recommended name:
    TPA-induced transmembrane protein
    Protein Accession:
    Q5BVD1
    Secondary Accessions:
    • B4DNV2
    • B4E0Z2
    • Q96AJ4
    • Q9H5Q1

    Protein attributes for C3orf52 Gene

    Size:
    217 amino acids
    Molecular mass:
    24295 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH17064.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB15569.1; Type=Frameshift; Positions=1; Evidence={ECO:0000305}; Sequence=BAG60364.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for C3orf52 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C3orf52 Gene

Proteomics data for C3orf52 Gene at MOPED

Post-translational modifications for C3orf52 Gene

No Post-translational modifications

Other Protein References for C3orf52 Gene

No data available for DME Specific Peptides for C3orf52 Gene

Domains for C3orf52 Gene

Protein Domains for C3orf52 Gene

ProtoNet:
genes like me logo Genes that share domains with C3orf52: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C3orf52 Gene

Function for C3orf52 Gene

Molecular function for C3orf52 Gene

UniProtKB/Swiss-Prot Induction: Up-regulated following treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA) in the pancreatic cancer cell line HPAF-II. The up-regulation by TPA is triggered at the promoter level.

Gene Ontology (GO) - Molecular Function for C3orf52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C3orf52: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C3orf52 Gene

Localization for C3orf52 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C3orf52 Gene

Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C3orf52 Gene COMPARTMENTS Subcellular localization image for C3orf52 gene
Compartment Confidence
endoplasmic reticulum 5
plasma membrane 3
cytosol 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C3orf52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum --
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C3orf52: view

Pathways for C3orf52 Gene

SuperPathways for C3orf52 Gene

No Data Available

Interacting Proteins for C3orf52 Gene

Gene Ontology (GO) - Biological Process for C3orf52 Gene

None

No data available for Pathways by source for C3orf52 Gene

Transcripts for C3orf52 Gene

Unigene Clusters for C3orf52 Gene

Chromosome 3 open reading frame 52:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf52 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10
SP1: - - - -
SP2: - - - - - - - -
SP3:
SP4: -
SP5: -

Relevant External Links for C3orf52 Gene

GeneLoc Exon Structure for
C3orf52
ECgene alternative splicing isoforms for
C3orf52

Expression for C3orf52 Gene

mRNA expression in normal human tissues for C3orf52 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C3orf52 Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (9.2), Skin - Not Sun Exposed (Suprapubic) (8.8), and Pancreas (6.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C3orf52 Gene

SOURCE GeneReport for Unigene cluster for C3orf52 Gene Hs.434247

genes like me logo Genes that share expressions with C3orf52: view

Orthologs for C3orf52 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C3orf52 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C3H3orf52 36
  • 98.77 (n)
  • 97.24 (a)
C3orf52 37
  • 63 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C1H3orf52 36
  • 79.42 (n)
  • 64.98 (a)
C3orf52 37
  • 43 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C33H3orf52 36
  • 79.3 (n)
  • 70.33 (a)
C3orf52 37
  • 39 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC016579 36
  • 76.01 (n)
  • 69.16 (a)
BC016579 16
BC016579 37
  • 41 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C3orf52 37
  • 24 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC685680 36
  • 76.21 (n)
  • 67.48 (a)
chicken
(Gallus gallus)
Aves C1H3ORF52 36
  • 52.38 (n)
  • 43.96 (a)
C3orf52 37
  • 17 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C3orf52 37
  • 19 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c3orf52 36
  • 47.13 (n)
  • 37.36 (a)
Species with no ortholog for C3orf52:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf52 Gene

ENSEMBL:
Gene Tree for C3orf52 (if available)
TreeFam:
Gene Tree for C3orf52 (if available)

Paralogs for C3orf52 Gene

Selected SIMAP similar genes for C3orf52 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with C3orf52: view

No data available for Paralogs for C3orf52 Gene

Variants for C3orf52 Gene

Sequence variations from dbSNP and Humsavar for C3orf52 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs11824 -- 112,117,719(-) CCCCA(A/G)ATAGC utr-variant-3-prime
rs173108 -- 112,101,583(+) AATTT(C/T)GAGGA intron-variant
rs186866 -- 112,099,231(+) aaatt(A/G)cccag intron-variant
rs189302 -- 112,104,242(-) TTCCA(C/T)CTTCC intron-variant
rs191455 -- 112,101,103(+) AACAA(G/T)TAAGG intron-variant

Relevant External Links for C3orf52 Gene

HapMap Linkage Disequilibrium report
C3orf52

No data available for Structural Variations from Database of Genomic Variants (DGV) for C3orf52 Gene

Disorders for C3orf52 Gene

No disorders were found for C3orf52 Gene.

No data available for UniProtKB/Swiss-Prot for C3orf52 Gene

Publications for C3orf52 Gene

  1. Identification and in silico characterization of a novel gene: TPA induced trans-membrane protein. (PMID: 15737651) Chan C.-Y. … Adrian T.E. (Biochem. Biophys. Res. Commun. 2005) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for C3orf52 Gene

Sources for C3orf52 Gene

Back to Top

Content