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Aliases for C3orf49 Gene

Subcategory (RNA class) for C3orf49 Gene

ncRNA

Quality Score for this RNA gene is

13

Aliases for C3orf49 Gene

  • Chromosome 3 Open Reading Frame 49 2 3 5

External Ids for C3orf49 Gene

Previous GeneCards Identifiers for C3orf49 Gene

  • GC03P063782

Summaries for C3orf49 Gene

GeneCards Summary for C3orf49 Gene

C3orf49 (Chromosome 3 Open Reading Frame 49) is an RNA Gene, and is affiliated with the ncRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf49 Gene

Genomics for C3orf49 Gene

Regulatory Elements for C3orf49 Gene

Enhancers for C3orf49 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C3orf49 on UCSC Golden Path with GeneCards custom track

Genomic Location for C3orf49 Gene

Chromosome:
3
Start:
63,819,362 bp from pter
End:
63,848,636 bp from pter
Size:
29,275 bases
Orientation:
Plus strand

Genomic View for C3orf49 Gene

Genes around C3orf49 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C3orf49 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C3orf49 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf49 Gene

Proteins for C3orf49 Gene

  • Protein details for C3orf49 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96BT1-CC049_HUMAN
    Recommended name:
    Putative uncharacterized protein C3orf49
    Protein Accession:
    Q96BT1

    Protein attributes for C3orf49 Gene

    Size:
    292 amino acids
    Molecular mass:
    33461 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C3orf49 Gene

Proteomics data for C3orf49 Gene at MOPED

Post-translational modifications for C3orf49 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C3orf49 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for C3orf49 Gene

Domains & Families for C3orf49 Gene

Protein Domains for C3orf49 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf49: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf49 Gene

Function for C3orf49 Gene

Phenotypes for C3orf49 Gene

GenomeRNAi human phenotypes for C3orf49:
genes like me logo Genes that share phenotypes with C3orf49: view

miRNA for C3orf49 Gene

miRTarBase miRNAs that target C3orf49

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C3orf49 Gene

Localization for C3orf49 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C3orf49 Gene COMPARTMENTS Subcellular localization image for C3orf49 gene
Compartment Confidence
nucleus 3
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C3orf49 Gene

Pathways & Interactions for C3orf49 Gene

SuperPathways for C3orf49 Gene

No Data Available

Interacting Proteins for C3orf49 Gene

Gene Ontology (GO) - Biological Process for C3orf49 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C3orf49 Gene

Drugs & Compounds for C3orf49 Gene

No Compound Related Data Available

Transcripts for C3orf49 Gene

mRNA/cDNA for C3orf49 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C3orf49 Gene

Chromosome 3 open reading frame 49:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf49 Gene

No ASD Table

Relevant External Links for C3orf49 Gene

GeneLoc Exon Structure for
C3orf49
ECgene alternative splicing isoforms for
C3orf49

Expression for C3orf49 Gene

mRNA expression in normal human tissues for C3orf49 Gene

mRNA differential expression in normal tissues according to GTEx for C3orf49 Gene

This gene is overexpressed in Testis (x5.6).

Protein differential expression in normal tissues from HIPED for C3orf49 Gene

This gene is overexpressed in Blymphocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C3orf49 Gene



SOURCE GeneReport for Unigene cluster for C3orf49 Gene Hs.506386

genes like me logo Genes that share expression patterns with C3orf49: view

Protein tissue co-expression partners for C3orf49 Gene

- Elite partner

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C3orf49 Gene

Orthologs for C3orf49 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C3orf49 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C3orf49 36
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C3orf49 36
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C3orf49 36
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C3orf49 36
  • 67 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C3orf49 36
  • 99 (a)
OneToOne
Species with no ortholog for C3orf49:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf49 Gene

ENSEMBL:
Gene Tree for C3orf49 (if available)
TreeFam:
Gene Tree for C3orf49 (if available)

Paralogs for C3orf49 Gene

Pseudogenes.org Pseudogenes for C3orf49 Gene

genes like me logo Genes that share paralogs with C3orf49: view

No data available for Paralogs for C3orf49 Gene

Variants for C3orf49 Gene

Sequence variations from dbSNP and Humsavar for C3orf49 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs2291533 -- 63,831,754(-) TCACA(C/G)TGTTG nc-transcript-variant
rs7614311 -- 63,827,978(+) TTCTC(A/C)CTCTT intron-variant
rs10692305 -- 63,830,986(+) TTGTT(-/TGTT)ATGTG intron-variant
rs2130990 -- 63,826,924(-) TCGCA(C/T)AGGCT intron-variant
rs17069439 -- 63,828,025(+) CATAC(C/T)ATGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C3orf49 Gene

Variant ID Type Subtype PubMed ID
nsv876886 CNV Gain 21882294

Variation tolerance for C3orf49 Gene

Gene Damage Index Score: 7.14; 80.69% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C3orf49 Gene

HapMap Linkage Disequilibrium report
C3orf49

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf49 Gene

Disorders for C3orf49 Gene

Relevant External Links for C3orf49

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C3orf49

No disorders were found for C3orf49 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf49 Gene

Publications for C3orf49 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) (Nature 2014) 3
  4. Gene network analysis in a pediatric cohort identifies novel lung function genes. (PMID: 24023788) Ong B.A. … Hakonarson H. (PLoS ONE 2013) 3
  5. Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. (PMID: 15203218) Fu G.K. … Stuve L.L. (Genomics 2004) 3

Products for C3orf49 Gene

Sources for C3orf49 Gene

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