C3orf49 Gene
protein-coding GIFtS: 32
GCID: GC03P063782
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chromosome 3 open reading frame 49
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Aliases
for C3orf49 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| Chromosome 3 Open Reading Frame 491 2 |
| External Ids: | HGNC: 251901 | Entrez Gene: 1322002 | Ensembl: ENSG000001636327 | UniProtKB: Q96BT13 | | ORGUL members: | |
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| NONCODE:n407411 | |
Export aliases for C3orf49 gene to outside databases
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Summaries
for C3orf49 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C3orf49 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C3orf49 gene promoter:
AP-1 AML1a POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) Tal-1beta POU3F2 E47 N-Myc ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C3orf49
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C3orf49 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p14.1 Ensembl cytogenetic band: 3p14.1 HGNC cytogenetic band: 3p14.1C3orf49 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P063782: view genomic region
(about GC identifiers)
Start:
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63,805,038 bp from pter |
End:
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63,834,312 bp from pter |
Size:
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29,275 bases |
Orientation:
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plus strand |
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Proteins
for C3orf49 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CC049_HUMAN, Q96BT1 (See
protein sequence)Recommended Name: Putative uncharacterized protein C3orf49 Size: 292 amino acids; 33461 DaExplore the universe of human proteins at neXtProt for C3orf49: NX_Q96BT1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96BT1
C3orf49 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000295896
Human Recombinant Protein Products for C3orf49:
C3orf49 Antibody Products:
Assay Products for C3orf49: |
Protein
Domains /
Families
for C3orf49 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q96BT1 |
Function
for C3orf49 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Animal Models:
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C3orf49 |
|
Pathways & Interactions
for C3orf49 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C3orf49
|
Drugs & Compounds
for C3orf49 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C3orf49
Search CenterWatch for drugs/clinical trials and news about C3orf49 / CC049 
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Transcripts
for C3orf49 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C3orf49 gene: NM_138808.1 Unigene Cluster for C3orf49: Chromosome 3 open reading frame 49 Hs.506386 [show with all ESTs]Unigene Representative Sequence: NR_0268662 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000295896(uc003dls.4) ENST00000491896
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C3orf49
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C3orf49 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C3orf49 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C3orf49 |
Additional cDNA sequence: BC015210.1 NR_026866.1 2 DOTS entries: DT.40295986 DT.75154086 14 AceView cDNA sequences: BC015210 NM_138808 AA448918 BQ220948 BE790096 AW628563 BG198837 BG220703 BF915438 CD636568 BG200778 BF914079 BQ379781 BF914527
GeneLoc Exon Structure
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Expression
for C3orf49 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C3orf49 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTTTAACCT
About this image
See C3orf49 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C3orf49
SOURCE GeneReport for Unigene cluster: Hs.506386
SABiosciences Custom PCR Arrays for C3orf49
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C3orf49
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C3orf49 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C3orf49 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C3orf49 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C3orf49 |
Orthologs
for C3orf49 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for C3orf49 (if available)
TreeFam Gene Tree for C3orf49 (if available) |
Paralogs
for C3orf49 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C3orf49 gene
C3orf49 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for C3orf49
PGOHUM00000241913
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Genomic Variants
for C3orf49 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for C3orf49 (63805038 - 63834312 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C3orf49: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for C3orf49 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C3orf49 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C3orf49 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C3orf49) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (2006)
- Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. (PubMed id 15203218)1 Fu G.K....Stuve L.L. (2004)
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External Searches for C3orf49 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C3orf49 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing C3orf49 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C3orf49 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C3orf49 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C3orf49 gene:
Search GeneIP for patents involving C3orf49
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C3orf49 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C3orf49 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C3orf49 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C3orf49 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C3orf49 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C3orf49 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C3orf49 |
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 |  |  |  | |
| | | | Search Tocris compounds for C3orf49 |
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 | | | C3orf49 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C3orf49 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for C3orf49 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C3orf49 |
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