Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C3orf38 Gene

Aliases for C3orf38 Gene

  • Chromosome 3 Open Reading Frame 38 2 3

External Ids for C3orf38 Gene

Previous GeneCards Identifiers for C3orf38 Gene

  • GC03P088282
  • GC03P088198

Summaries for C3orf38 Gene

GeneCards Summary for C3orf38 Gene

C3orf38 (Chromosome 3 Open Reading Frame 38) is a Protein Coding gene.

UniProtKB/Swiss-Prot for C3orf38 Gene

  • May be involved in apoptosis regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf38 Gene

Genomics for C3orf38 Gene

Regulatory Elements for C3orf38 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C3orf38 Gene

88,149,743 bp from pter
88,168,729 bp from pter
18,987 bases
Plus strand

Genomic View for C3orf38 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C3orf38 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf38 Gene

Proteins for C3orf38 Gene

  • Protein details for C3orf38 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C3orf38
    Protein Accession:
    Secondary Accessions:
    • B2R8X6
    • Q8TC85

    Protein attributes for C3orf38 Gene

    329 amino acids
    Molecular mass:
    37541 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C3orf38 Gene


neXtProt entry for C3orf38 Gene

Proteomics data for C3orf38 Gene at MOPED

Post-translational modifications for C3orf38 Gene

  • Ubiquitination at Lys 318
  • Modification sites at PhosphoSitePlus

Other Protein References for C3orf38 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C3orf38 Gene

Domains & Families for C3orf38 Gene

Protein Domains for C3orf38 Gene


Suggested Antigen Peptide Sequences for C3orf38 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf38: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C3orf38 Gene

Function for C3orf38 Gene

Molecular function for C3orf38 Gene

UniProtKB/Swiss-Prot Function:
May be involved in apoptosis regulation.

Phenotypes for C3orf38 Gene

genes like me logo Genes that share phenotypes with C3orf38: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C3orf38

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C3orf38 Gene

Localization for C3orf38 Gene

Subcellular locations from

Jensen Localization Image for C3orf38 Gene COMPARTMENTS Subcellular localization image for C3orf38 gene
Compartment Confidence
cytosol 2
nucleus 2
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C3orf38 Gene

Pathways & Interactions for C3orf38 Gene

SuperPathways for C3orf38 Gene

No Data Available

Interacting Proteins for C3orf38 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000322469 for C3orf38 Gene via STRING

Gene Ontology (GO) - Biological Process for C3orf38 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptotic process IEA --
genes like me logo Genes that share ontologies with C3orf38: view

No data available for Pathways by source and SIGNOR curated interactions for C3orf38 Gene

Drugs & Compounds for C3orf38 Gene

No Compound Related Data Available

Transcripts for C3orf38 Gene

mRNA/cDNA for C3orf38 Gene

Unigene Clusters for C3orf38 Gene

Chromosome 3 open reading frame 38:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C3orf38

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf38 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b
SP1: -
SP2: -

Relevant External Links for C3orf38 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C3orf38 Gene

mRNA expression in normal human tissues for C3orf38 Gene

Protein differential expression in normal tissues from HIPED for C3orf38 Gene

This gene is overexpressed in Fetal ovary (41.7) and Peripheral blood mononuclear cells (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C3orf38 Gene

SOURCE GeneReport for Unigene cluster for C3orf38 Gene Hs.518099

genes like me logo Genes that share expression patterns with C3orf38: view

Protein tissue co-expression partners for C3orf38 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C3orf38 Gene

Orthologs for C3orf38 Gene

This gene was present in the common ancestor of animals.

Orthologs for C3orf38 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C1H3orf38 35
  • 88.96 (n)
  • 86.17 (a)
C3orf38 36
  • 85 (a)
(Canis familiaris)
Mammalia C33H3orf38 35
  • 89.57 (n)
  • 87.42 (a)
C3orf38 36
  • 84 (a)
(Mus musculus)
Mammalia 4930453N24Rik 35
  • 85.99 (n)
  • 84.66 (a)
4930453N24Rik 16
4930453N24Rik 36
  • 79 (a)
(Pan troglodytes)
Mammalia C3H3orf38 35
  • 99.59 (n)
  • 99.7 (a)
C3orf38 36
  • 100 (a)
(Monodelphis domestica)
Mammalia C3orf38 36
  • 54 (a)
(Ornithorhynchus anatinus)
Mammalia C3orf38 36
  • 62 (a)
(Gallus gallus)
Aves C1H3ORF38 35
  • 66.78 (n)
  • 57.63 (a)
C3orf38 36
  • 54 (a)
(Anolis carolinensis)
Reptilia C3orf38 36
  • 56 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c3orf38 35
  • 56.89 (n)
  • 49.67 (a)
(Danio rerio)
Actinopterygii LOC100330300 35
  • 56.96 (n)
  • 52.63 (a)
C9H3orf38 36
  • 49 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13876 35
  • 43.11 (n)
  • 28.51 (a)
CG13876 36
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 32 (a)
Species with no ortholog for C3orf38:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C3orf38 Gene

Gene Tree for C3orf38 (if available)
Gene Tree for C3orf38 (if available)

Paralogs for C3orf38 Gene Pseudogenes for C3orf38 Gene

genes like me logo Genes that share paralogs with C3orf38: view

No data available for Paralogs for C3orf38 Gene

Variants for C3orf38 Gene

Sequence variations from dbSNP and Humsavar for C3orf38 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs5850832 -- 88,152,772(+) AAAAA(-/A)GAAAT intron-variant
rs6551279 -- 88,152,154(+) ctcac(A/G)cctgt intron-variant
rs6551280 -- 88,152,589(+) aaccc(C/T)gtctg intron-variant
rs6781333 -- 88,157,381(+) TTCAG(A/C)CAACA utr-variant-3-prime
rs7427416 -- 88,156,698(+) AAGCG(C/T)TAAGT utr-variant-3-prime

Variation tolerance for C3orf38 Gene

Residual Variation Intolerance Score: 66.18% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.59; 30.59% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C3orf38 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C3orf38 Gene

Disorders for C3orf38 Gene

Relevant External Links for C3orf38

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C3orf38: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf38 Gene

Publications for C3orf38 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 67
  4. Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study. (PMID: 21177773) Moyer A.M. … Weinshilboum R.M. (Toxicol. Sci. 2011) 67
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 67

Products for C3orf38 Gene

Sources for C3orf38 Gene

Back to Top