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Aliases for C3orf36 Gene

Aliases for C3orf36 Gene

  • Chromosome 3 Open Reading Frame 36 2 3 5

External Ids for C3orf36 Gene

Previous GeneCards Identifiers for C3orf36 Gene

  • GC03M135130
  • GC03M133646
  • GC03M131025

Summaries for C3orf36 Gene

GeneCards Summary for C3orf36 Gene

C3orf36 (Chromosome 3 Open Reading Frame 36) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf36 Gene

Genomics for C3orf36 Gene

Regulatory Elements for C3orf36 Gene

Enhancers for C3orf36 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F133805 1 ENCODE 21.5 +123.7 123711 2.0 PKNOX1 ATF1 CREB3L1 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF48 ZNF2 SRPRB C3orf36 RYK SLCO2A1 HMGB3P14 LOC105374116 GC03P133813 PIR63043
GH03F134030 0.5 FANTOM5 31.1 -99.3 -99284 0.1 TGIF2 TFAP4 SUZ12 EZH2 C3orf36 SLCO2A1 GC03M133943
GH03F133967 0.5 FANTOM5 27.1 -38.2 -38170 0.3 ZFHX2 EGR2 C3orf36 SLCO2A1 GC03M133943
GH03F134248 1.3 FANTOM5 ENCODE 10.2 -321.4 -321424 4.5 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF48 GLIS2 ELK1 ZNF207 REST C3orf36 RYK LINC02004
GH03F134224 1.2 Ensembl ENCODE 10.5 -294.7 -294689 1.0 SIN3A FEZF1 ZNF48 ZNF2 ZNF143 FOS ZNF202 ZNF263 MEF2D SMARCA4 RYK TOPBP1 C3orf36 GC03P134171
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C3orf36 on UCSC Golden Path with GeneCards custom track

Genomic Location for C3orf36 Gene

133,928,145 bp from pter
133,929,812 bp from pter
1,668 bases
Minus strand

Genomic View for C3orf36 Gene

Genes around C3orf36 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C3orf36 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C3orf36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf36 Gene

Proteins for C3orf36 Gene

  • Protein details for C3orf36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C3orf36
    Protein Accession:
    Secondary Accessions:
    • Q3SXR3
    • Q9H6K8

    Protein attributes for C3orf36 Gene

    165 amino acids
    Molecular mass:
    16908 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C3orf36 Gene

Post-translational modifications for C3orf36 Gene

No Post-translational modifications

Other Protein References for C3orf36 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C3orf36 Gene

Domains & Families for C3orf36 Gene

Protein Domains for C3orf36 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf36: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf36 Gene

Function for C3orf36 Gene

genes like me logo Genes that share phenotypes with C3orf36: view

Animal Model Products

miRNA for C3orf36 Gene

miRTarBase miRNAs that target C3orf36

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C3orf36 Gene

Localization for C3orf36 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C3orf36 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C3orf36 Gene

Pathways & Interactions for C3orf36 Gene

SuperPathways for C3orf36 Gene

No Data Available

Interacting Proteins for C3orf36 Gene

Selected Interacting proteins: Q3SXR2-CC036_HUMAN for C3orf36 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for C3orf36 Gene


No data available for Pathways by source and SIGNOR curated interactions for C3orf36 Gene

Transcripts for C3orf36 Gene

mRNA/cDNA for C3orf36 Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(9) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C3orf36 Gene

Chromosome 3 open reading frame 36:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf36 Gene

No ASD Table

Relevant External Links for C3orf36 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C3orf36 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C3orf36 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C3orf36 Gene

This gene is overexpressed in Lung (x10.1) and Kidney - Cortex (x4.0).

NURSA nuclear receptor signaling pathways regulating expression of C3orf36 Gene:


SOURCE GeneReport for Unigene cluster for C3orf36 Gene:

genes like me logo Genes that share expression patterns with C3orf36: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C3orf36 Gene

Orthologs for C3orf36 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C3orf36 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C3H3orf36 34
  • 99.19 (n)
Species where no ortholog for C3orf36 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf36 Gene

Gene Tree for C3orf36 (if available)
Gene Tree for C3orf36 (if available)

Paralogs for C3orf36 Gene

No data available for Paralogs for C3orf36 Gene

Variants for C3orf36 Gene

Sequence variations from dbSNP and Humsavar for C3orf36 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs112524521 -- 133,927,946(+) GCTTC(A/G)GATGT downstream-variant-500B
rs112653603 -- 133,931,154(+) TTTTC(C/T)GGCTT upstream-variant-2KB
rs114032826 -- 133,930,336(+) GGACC(C/T)TTCTT upstream-variant-2KB
rs115745591 -- 133,929,131(+) ATCAG(A/G)TAGTA utr-variant-5-prime
rs116556677 -- 133,929,575(+) AGCCC(C/T)GCAAA utr-variant-5-prime

Variation tolerance for C3orf36 Gene

Residual Variation Intolerance Score: 77.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.92; 35.78% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C3orf36 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C3orf36 Gene

Disorders for C3orf36 Gene

Relevant External Links for C3orf36

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C3orf36 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf36 Gene

Publications for C3orf36 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64

Products for C3orf36 Gene

Sources for C3orf36 Gene

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