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Aliases for C3orf22 Gene

Aliases for C3orf22 Gene

  • Chromosome 3 Open Reading Frame 22 2 3

External Ids for C3orf22 Gene

Previous GeneCards Identifiers for C3orf22 Gene

  • GC03M127752
  • GC03M126267
  • GC03M123648

Summaries for C3orf22 Gene

GeneCards Summary for C3orf22 Gene

C3orf22 (Chromosome 3 Open Reading Frame 22) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf22 Gene

Genomics for C3orf22 Gene

Regulatory Elements for C3orf22 Gene

Transcription factor binding sites by QIAGEN in the C3orf22 gene promoter:

Genomic Location for C3orf22 Gene

126,521,997 bp from pter
126,558,965 bp from pter
36,969 bases
Minus strand

Genomic View for C3orf22 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C3orf22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf22 Gene

Proteins for C3orf22 Gene

  • Protein details for C3orf22 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C3orf22
    Protein Accession:
    Secondary Accessions:
    • B3KUS9

    Protein attributes for C3orf22 Gene

    141 amino acids
    Molecular mass:
    15686 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C3orf22 Gene


neXtProt entry for C3orf22 Gene

Proteomics data for C3orf22 Gene at MOPED

Post-translational modifications for C3orf22 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C3orf22 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C3orf22 Gene

Domains & Families for C3orf22 Gene

Protein Domains for C3orf22 Gene


Suggested Antigen Peptide Sequences for C3orf22 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf22: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C3orf22 Gene

Function for C3orf22 Gene

Phenotypes for C3orf22 Gene

genes like me logo Genes that share phenotypes with C3orf22: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C3orf22

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C3orf22 Gene

Localization for C3orf22 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C3orf22 Gene

Pathways & Interactions for C3orf22 Gene

SuperPathways for C3orf22 Gene

No Data Available

Interacting Proteins for C3orf22 Gene

Gene Ontology (GO) - Biological Process for C3orf22 Gene


No data available for Pathways by source and SIGNOR curated interactions for C3orf22 Gene

Drugs & Compounds for C3orf22 Gene

No Compound Related Data Available

Transcripts for C3orf22 Gene

mRNA/cDNA for C3orf22 Gene

(8) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(16) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C3orf22 Gene

Chromosome 3 open reading frame 22:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C3orf22

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf22 Gene

No ASD Table

Relevant External Links for C3orf22 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C3orf22 Gene

mRNA expression in normal human tissues for C3orf22 Gene

mRNA differential expression in normal tissues according to GTEx for C3orf22 Gene

This gene is overexpressed in Testis (x50.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C3orf22 Gene

SOURCE GeneReport for Unigene cluster for C3orf22 Gene Hs.178210

genes like me logo Genes that share expression patterns with C3orf22: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C3orf22 Gene

Orthologs for C3orf22 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C3orf22 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C3H3orf22 35
  • 72.78 (n)
  • 64.22 (a)
C3H3orf22 36
  • 51 (a)
(Canis familiaris)
Mammalia C20H3orf22 35
  • 77.06 (n)
  • 65.59 (a)
C3orf22 36
  • 58 (a)
(Mus musculus)
Mammalia BC048671 16
BC048671 36
  • 46 (a)
(Pan troglodytes)
Mammalia C3orf22 36
  • 98 (a)
Species with no ortholog for C3orf22:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf22 Gene

Gene Tree for C3orf22 (if available)
Gene Tree for C3orf22 (if available)

Paralogs for C3orf22 Gene

No data available for Paralogs for C3orf22 Gene

Variants for C3orf22 Gene

Sequence variations from dbSNP and Humsavar for C3orf22 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs869463 -- 126,550,075(+) GCCCC(A/G)AGCCT reference, synonymous-codon, intron-variant
rs869464 -- 126,550,110(+) TGGCC(A/G/T)TCAGG intron-variant
rs1123373 -- 126,546,863(-) tgagt(A/G)gtttt intron-variant
rs1490747 -- 126,553,052(-) TGCTT(C/G)CCCAA intron-variant
rs1490748 -- 126,550,987(-) GAAGC(A/G)ATGGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C3orf22 Gene

Variant ID Type Subtype PubMed ID
nsv877432 CNV Loss 21882294
nsv829717 CNV Loss 17160897
dgv5246n71 CNV Loss 21882294
esv2658491 CNV Deletion 23128226
esv2725872 CNV Deletion 23290073

Variation tolerance for C3orf22 Gene

Residual Variation Intolerance Score: 37.44% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.50; 10.85% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C3orf22 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf22 Gene

Disorders for C3orf22 Gene

Relevant External Links for C3orf22

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C3orf22: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf22 Gene

Publications for C3orf22 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for C3orf22 Gene

Sources for C3orf22 Gene

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