Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C3orf20 Gene

Aliases for C3orf20 Gene

  • Chromosome 3 Open Reading Frame 20 2 3 5

External Ids for C3orf20 Gene

Previous GeneCards Identifiers for C3orf20 Gene

  • GC03P014692

Summaries for C3orf20 Gene

GeneCards Summary for C3orf20 Gene

C3orf20 (Chromosome 3 Open Reading Frame 20) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf20 Gene

Genomics for C3orf20 Gene

Regulatory Elements for C3orf20 Gene

Genomic Location for C3orf20 Gene

Chromosome:
3
Start:
14,674,225 bp from pter
End:
14,773,036 bp from pter
Size:
98,812 bases
Orientation:
Plus strand

Genomic View for C3orf20 Gene

Genes around C3orf20 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C3orf20 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C3orf20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf20 Gene

Proteins for C3orf20 Gene

  • Protein details for C3orf20 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8ND61-CC020_HUMAN
    Recommended name:
    Uncharacterized protein C3orf20
    Protein Accession:
    Q8ND61
    Secondary Accessions:
    • Q7L0U6
    • Q8NCP2
    • Q9H0I7

    Protein attributes for C3orf20 Gene

    Size:
    904 amino acids
    Molecular mass:
    101266 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C3orf20 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C3orf20 Gene

Proteomics data for C3orf20 Gene at MOPED

Post-translational modifications for C3orf20 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C3orf20 Gene

No data available for DME Specific Peptides for C3orf20 Gene

Domains & Families for C3orf20 Gene

Protein Domains for C3orf20 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf20: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C3orf20 Gene

Function for C3orf20 Gene

Phenotypes for C3orf20 Gene

genes like me logo Genes that share phenotypes with C3orf20: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C3orf20 Gene

Localization for C3orf20 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C3orf20 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C3orf20 Gene COMPARTMENTS Subcellular localization image for C3orf20 gene
Compartment Confidence
cytosol 2
nucleus 2
endoplasmic reticulum 1
golgi apparatus 1
mitochondrion 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for C3orf20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with C3orf20: view

Pathways & Interactions for C3orf20 Gene

SuperPathways for C3orf20 Gene

No Data Available

Interacting Proteins for C3orf20 Gene

Gene Ontology (GO) - Biological Process for C3orf20 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C3orf20 Gene

Drugs & Compounds for C3orf20 Gene

No Compound Related Data Available

Transcripts for C3orf20 Gene

mRNA/cDNA for C3orf20 Gene

Unigene Clusters for C3orf20 Gene

Chromosome 3 open reading frame 20:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf20 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
SP1: - -
SP2: -
SP3:

Relevant External Links for C3orf20 Gene

GeneLoc Exon Structure for
C3orf20
ECgene alternative splicing isoforms for
C3orf20

Expression for C3orf20 Gene

mRNA expression in normal human tissues for C3orf20 Gene

mRNA differential expression in normal tissues according to GTEx for C3orf20 Gene

This gene is overexpressed in Testis (x35.2).

Protein differential expression in normal tissues from HIPED for C3orf20 Gene

This gene is overexpressed in Heart (23.2), Tlymphocyte (10.8), Fetal gut (10.0), Kidney (9.4), and CD8 Tcells (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C3orf20 Gene



SOURCE GeneReport for Unigene cluster for C3orf20 Gene Hs.661452

genes like me logo Genes that share expression patterns with C3orf20: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C3orf20 Gene

Orthologs for C3orf20 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C3orf20 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C22H3orf20 35
  • 78.73 (n)
  • 70.49 (a)
C3orf20 36
  • 66 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C20H3orf20 35
  • 79.57 (n)
  • 71.27 (a)
C3orf20 36
  • 66 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4930590J08Rik 35
  • 74.24 (n)
  • 66.07 (a)
4930590J08Rik 16
4930590J08Rik 36
  • 63 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C3H3orf20 35
  • 99.26 (n)
  • 99.22 (a)
C3orf20 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1560289 35
  • 74.43 (n)
  • 65.58 (a)
oppossum
(Monodelphis domestica)
Mammalia C3orf20 36
  • 29 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 38 (a)
OneToMany
-- 36
  • 36 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia C3orf20 36
  • 35 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 20 (a)
OneToOne
Species with no ortholog for C3orf20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C3orf20 Gene

ENSEMBL:
Gene Tree for C3orf20 (if available)
TreeFam:
Gene Tree for C3orf20 (if available)

Paralogs for C3orf20 Gene

No data available for Paralogs for C3orf20 Gene

Variants for C3orf20 Gene

Sequence variations from dbSNP and Humsavar for C3orf20 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs17040196 -, - 14,704,350(+) AAAGG(A/G)CCACA intron-variant, reference, missense
rs17040154 - 14,682,838(+) AAAAG(A/G)CATCA intron-variant, upstream-variant-2KB, reference, missense
rs9821143 - 14,682,906(+) CGTCC(A/G)ACATC intron-variant, upstream-variant-2KB, reference, missense
rs17852774 - 14,690,060(+) CTCTT(A/C)CACAG reference, missense, utr-variant-5-prime
rs6765537 - 14,714,065(+) GAACC(A/G)TCACC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C3orf20 Gene

Variant ID Type Subtype PubMed ID
esv2724945 CNV Deletion 23290073
nsv876576 CNV Loss 21882294
nsv508210 CNV Loss 20534489
nsv876578 CNV Gain+Loss 21882294
esv33420 CNV Gain 17666407
esv2658697 CNV Deletion 23128226
nsv520162 CNV Loss 19592680
nsv507082 CNV Insertion 20534489
esv2671265 CNV Deletion 23128226
nsv876579 CNV Gain 21882294
esv2724959 CNV Deletion 23290073
esv2667245 CNV Deletion 23128226

Variation tolerance for C3orf20 Gene

Residual Variation Intolerance Score: 93.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 19.88; 98.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C3orf20 Gene

HapMap Linkage Disequilibrium report
C3orf20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf20 Gene

Disorders for C3orf20 Gene

Relevant External Links for C3orf20

Genetic Association Database (GAD)
C3orf20
Human Genome Epidemiology (HuGE) Navigator
C3orf20
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C3orf20

No disorders were found for C3orf20 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C3orf20 Gene

Publications for C3orf20 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for C3orf20 Gene

Sources for C3orf20 Gene

Back to Top

Content