Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C3orf18 Gene

Aliases for C3orf18 Gene

  • Chromosome 3 Open Reading Frame 18 2 3
  • Uncharacterized Protein C3orf18 3
  • Protein G20 4
  • G20 3

External Ids for C3orf18 Gene

Summaries for C3orf18 Gene

GeneCards Summary for C3orf18 Gene

C3orf18 (Chromosome 3 Open Reading Frame 18) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C3orf18 Gene

Genomics for C3orf18 Gene

Regulatory Elements for C3orf18 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C3orf18 Gene

50,558,025 bp from pter
50,571,027 bp from pter
13,003 bases
Minus strand

Genomic View for C3orf18 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C3orf18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C3orf18 Gene

Proteins for C3orf18 Gene

  • Protein details for C3orf18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C3orf18
    Protein Accession:
    Secondary Accessions:
    • C9JNP0

    Protein attributes for C3orf18 Gene

    162 amino acids
    Molecular mass:
    17468 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C3orf18 Gene


neXtProt entry for C3orf18 Gene

Proteomics data for C3orf18 Gene at MOPED

Post-translational modifications for C3orf18 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for C3orf18 Gene

Domains for C3orf18 Gene

Protein Domains for C3orf18 Gene


Suggested Antigen Peptide Sequences for C3orf18 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C3orf18: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C3orf18 Gene

Function for C3orf18 Gene

Animal Model Products

CRISPR Products

miRNA for C3orf18 Gene

miRTarBase miRNAs that target C3orf18

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C3orf18

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C3orf18 Gene

Localization for C3orf18 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C3orf18 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for C3orf18 Gene COMPARTMENTS Subcellular localization image for C3orf18 gene
Compartment Confidence
plasma membrane 2
cytosol 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C3orf18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C3orf18: view

Pathways for C3orf18 Gene

SuperPathways for C3orf18 Gene

No Data Available

Interacting Proteins for C3orf18 Gene

Gene Ontology (GO) - Biological Process for C3orf18 Gene


No data available for Pathways by source for C3orf18 Gene

Transcripts for C3orf18 Gene

Unigene Clusters for C3orf18 Gene

Chromosome 3 open reading frame 18:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C3orf18

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C3orf18 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d
SP1: - - - - - - -
SP2: - -
SP3: - - - -
SP6: - -
SP7: - - - - - - -

Relevant External Links for C3orf18 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C3orf18 Gene

mRNA expression in normal human tissues for C3orf18 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for C3orf18 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C3orf18 Gene

SOURCE GeneReport for Unigene cluster for C3orf18 Gene Hs.517860

genes like me logo Genes that share expressions with C3orf18: view

Expression partners for C3orf18 Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C3orf18 Gene

Orthologs for C3orf18 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C3orf18 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C22H3orf18 35
  • 89.92 (n)
  • 91.98 (a)
C22H3ORF18 36
  • 92 (a)
(Canis familiaris)
Mammalia C20H3orf18 35
  • 89.3 (n)
  • 91.36 (a)
C3orf18 36
  • 91 (a)
(Mus musculus)
Mammalia 6430571L13Rik 35
  • 85.19 (n)
  • 83.95 (a)
6430571L13Rik 16
6430571L13Rik 36
  • 83 (a)
(Pan troglodytes)
Mammalia C3H3orf18 35
  • 99.38 (n)
  • 98.15 (a)
C3ORF18 36
  • 98 (a)
(Rattus norvegicus)
Mammalia RGD1307461 35
  • 83.74 (n)
  • 85.19 (a)
(Monodelphis domestica)
Mammalia C3orf18 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia C3orf18 36
  • 69 (a)
(Gallus gallus)
Aves C12H3ORF18 35
  • 70.09 (n)
  • 69.23 (a)
C3orf18 36
  • 67 (a)
(Anolis carolinensis)
Reptilia C3orf18 36
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101732317 35
  • 68.09 (n)
  • 69.23 (a)
(Danio rerio)
Actinopterygii LOC101883833 35
  • 62.8 (n)
  • 69.64 (a)
C3orf18 (1 of 2) 36
  • 64 (a)
C6H3orf18 (2 of 2) 36
  • 47 (a)
Species with no ortholog for C3orf18:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C3orf18 Gene

Gene Tree for C3orf18 (if available)
Gene Tree for C3orf18 (if available)

Paralogs for C3orf18 Gene

Selected SIMAP similar genes for C3orf18 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with C3orf18: view

No data available for Paralogs for C3orf18 Gene

Variants for C3orf18 Gene

Sequence variations from dbSNP and Humsavar for C3orf18 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs364624 -- 50,561,308(-) TGACA(C/G)CTACT intron-variant
rs380853 -- 50,563,130(-) GGCCA(C/G)GCTGG intron-variant
rs386598 - 50,565,677(-) ATCTG(A/C)TAGGG missense, reference
rs387787 -- 50,558,501(-) CCCAT(A/C)TATGG utr-variant-3-prime
rs387834 -- 50,558,455(-) GGTCC(C/G)TGCAC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C3orf18 Gene

Variant ID Type Subtype PubMed ID
nsv876770 CNV Loss 21882294
nsv460532 CNV Loss 19166990
nsv460533 CNV Loss 19166990

Relevant External Links for C3orf18 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C3orf18 Gene

Disorders for C3orf18 Gene

Relevant External Links for C3orf18

Human Genome Epidemiology (HuGE) Navigator

No disorders were found for C3orf18 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C3orf18 Gene

Publications for C3orf18 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Host determinants of HIV-1 control in African Americans. (PMID: 20205591) Pelak K. … . (J. Infect. Dis. 2010) 3

Products for C3orf18 Gene

Sources for C3orf18 Gene

Back to Top