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Aliases for C2orf82 Gene

Aliases for C2orf82 Gene

  • Chromosome 2 Open Reading Frame 82 2 3 5
  • Uncharacterized Protein C2orf82 3
  • ASCL830 3
  • UNQ830 3

External Ids for C2orf82 Gene

Previous GeneCards Identifiers for C2orf82 Gene

  • GC02P233444
  • GC02P233721
  • GC02P225583

Summaries for C2orf82 Gene

GeneCards Summary for C2orf82 Gene

C2orf82 (Chromosome 2 Open Reading Frame 82) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf82 Gene

Genomics for C2orf82 Gene

Regulatory Elements for C2orf82 Gene

Enhancers for C2orf82 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F232900 1.3 FANTOM5 Ensembl ENCODE 21.4 +44.5 44528 1.8 TAF1 JUN MAX RAD21 ZIC2 POLR2A SMC3 FOSL2 FOS TCF7L2 NGEF C2orf82 LOC101928881 INPP5D PIR45244
GH02F232873 1.1 Ensembl ENCODE 20.3 +18.1 18092 4.9 ELF3 ARID4B SIN3A DMAP1 THRB ZNF48 DNMT3B RAD21 NFYC PPARG C2orf82 ENSG00000251485 NGEF GIGYF2 LOC101928881 KCNJ13 ATG16L1 SCARNA5 PIR45244
GH02F232836 1.4 FANTOM5 Ensembl ENCODE 14.3 -18.7 -18656 3.6 PKNOX1 BMI1 GATA2 FOS ZBTB2 ZEB2 TBX21 SMARCA4 PBX2 IKZF1 C2orf82 NGEF NEU2 ENSG00000199781
GH02F232872 0.9 ENCODE 22.1 +15.1 15096 0.2 ELF3 TBP ARID4B DMAP1 THRB ZNF48 ZSCAN9 RAD21 DNMT3B YY1 C2orf82 LOC101928881 NGEF PIR45244
GH02F232855 1.3 Ensembl ENCODE 14.5 +1.3 1335 6.8 ATF1 MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 NFYC ZHX2 MXD4 C2orf82 NGEF ATG16L1 SCARNA5 PIR45244
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C2orf82 on UCSC Golden Path with GeneCards custom track

Genomic Location for C2orf82 Gene

Chromosome:
2
Start:
232,857,270 bp from pter
End:
232,878,708 bp from pter
Size:
21,439 bases
Orientation:
Plus strand

Genomic View for C2orf82 Gene

Genes around C2orf82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C2orf82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C2orf82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf82 Gene

Proteins for C2orf82 Gene

  • Protein details for C2orf82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UX34-CB082_HUMAN
    Recommended name:
    Uncharacterized protein C2orf82
    Protein Accession:
    Q6UX34

    Protein attributes for C2orf82 Gene

    Size:
    121 amino acids
    Molecular mass:
    12073 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C2orf82 Gene

Post-translational modifications for C2orf82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C2orf82 Gene

Domains & Families for C2orf82 Gene

Protein Domains for C2orf82 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C2orf82: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C2orf82 Gene

Function for C2orf82 Gene

Phenotypes for C2orf82 Gene

genes like me logo Genes that share phenotypes with C2orf82: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C2orf82 Gene

Localization for C2orf82 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C2orf82 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C2orf82 gene
Compartment Confidence
plasma membrane 2
extracellular 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for C2orf82 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0071944 cell periphery IEA --
genes like me logo Genes that share ontologies with C2orf82: view

Pathways & Interactions for C2orf82 Gene

SuperPathways for C2orf82 Gene

No Data Available

Interacting Proteins for C2orf82 Gene

Gene Ontology (GO) - Biological Process for C2orf82 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C2orf82 Gene

Transcripts for C2orf82 Gene

Unigene Clusters for C2orf82 Gene

Chromosome 2 open reading frame 82:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf82 Gene

No ASD Table

Relevant External Links for C2orf82 Gene

GeneLoc Exon Structure for
C2orf82
ECgene alternative splicing isoforms for
C2orf82

Expression for C2orf82 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C2orf82 Gene

mRNA differential expression in normal tissues according to GTEx for C2orf82 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x9.4) and Brain - Substantia nigra (x4.6).

NURSA nuclear receptor signaling pathways regulating expression of C2orf82 Gene:

C2orf82

SOURCE GeneReport for Unigene cluster for C2orf82 Gene:

Hs.657509
genes like me logo Genes that share expression patterns with C2orf82: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C2orf82 Gene

Orthologs for C2orf82 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C2orf82 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C2orf82 35
  • 100 (a)
OneToOne
C2BH2orf82 34
  • 99.72 (n)
cow
(Bos Taurus)
Mammalia C3H2orf82 34
  • 88.43 (n)
C2orf82 35
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C25H2orf82 34
  • 86.14 (n)
C2orf82 35
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 3110079O15Rik 34 16 35
  • 79.06 (n)
chicken
(Gallus gallus)
Aves C9H2ORF82 34 35
  • 66.07 (n)
lizard
(Anolis carolinensis)
Reptilia C2orf82 35
  • 54 (a)
OneToOne
Species where no ortholog for C2orf82 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C2orf82 Gene

ENSEMBL:
Gene Tree for C2orf82 (if available)
TreeFam:
Gene Tree for C2orf82 (if available)

Paralogs for C2orf82 Gene

No data available for Paralogs for C2orf82 Gene

Variants for C2orf82 Gene

Sequence variations from dbSNP and Humsavar for C2orf82 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10172653 -- 232,872,123(+) GAGAG(C/T)GTTTG intron-variant
rs10172857 -- 232,872,295(+) AGCTA(C/T)TGAGG intron-variant
rs10208320 -- 232,863,813(+) TCTTA(A/G)AAAAA upstream-variant-2KB
rs111230801 -- 232,877,289(+) CCCTC(-/TA)AGAGA intron-variant, nc-transcript-variant, utr-variant-3-prime
rs111250815 -- 232,876,122(+) GCGGC(C/G)GTACG nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C2orf82 Gene

Variant ID Type Subtype PubMed ID
dgv4188n100 CNV gain 25217958
nsv1009825 CNV gain 25217958
nsv834570 CNV gain 17160897
nsv953203 CNV deletion 24416366

Relevant External Links for C2orf82 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C2orf82

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for C2orf82 Gene

Disorders for C2orf82 Gene

Relevant External Links for C2orf82

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C2orf82

No disorders were found for C2orf82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C2orf82 Gene

Publications for C2orf82 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4 64
  2. Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes. (PMID: 21624478) Heinonen J. … SAoAomAonen A.M. (Osteoarthr. Cartil. 2011) 2 3 64
  3. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) (Nature 2014) 3 64
  4. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PMID: 23453885) (Lancet 2013) 3 64
  5. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S. … Sullivan P.F. (Nat. Genet. 2013) 3 64

Products for C2orf82 Gene

Sources for C2orf82 Gene

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