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Aliases for C2orf80 Gene

Aliases for C2orf80 Gene

  • Chromosome 2 Open Reading Frame 80 2 3
  • Gonad Development Associated 1 2 3
  • GONDA1 3 6
  • Uncharacterized Protein C2orf80 3

External Ids for C2orf80 Gene

Previous GeneCards Identifiers for C2orf80 Gene

  • GC02M208739
  • GC02M209030
  • GC02M200878

Summaries for C2orf80 Gene

GeneCards Summary for C2orf80 Gene

C2orf80 (Chromosome 2 Open Reading Frame 80) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf80 Gene

Genomics for C2orf80 Gene

Regulatory Elements for C2orf80 Gene

Genomic Location for C2orf80 Gene

208,165,343 bp from pter
208,190,245 bp from pter
24,903 bases
Minus strand

Genomic View for C2orf80 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C2orf80 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf80 Gene

Proteins for C2orf80 Gene

  • Protein details for C2orf80 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C2orf80
    Protein Accession:
    Secondary Accessions:
    • A6NKZ3

    Protein attributes for C2orf80 Gene

    193 amino acids
    Molecular mass:
    22038 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C2orf80 Gene

Proteomics data for C2orf80 Gene at MOPED

Post-translational modifications for C2orf80 Gene

No Post-translational modifications

Other Protein References for C2orf80 Gene

No data available for DME Specific Peptides for C2orf80 Gene

Domains for C2orf80 Gene

Protein Domains for C2orf80 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C2orf80: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C2orf80 Gene

Function for C2orf80 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C2orf80 Gene

Localization for C2orf80 Gene

Subcellular locations from

Jensen Localization Image for C2orf80 Gene COMPARTMENTS Subcellular localization image for C2orf80 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C2orf80 Gene

Pathways for C2orf80 Gene

SuperPathways for C2orf80 Gene

No Data Available

Interacting Proteins for C2orf80 Gene

Gene Ontology (GO) - Biological Process for C2orf80 Gene


No data available for Pathways by source for C2orf80 Gene

Transcripts for C2orf80 Gene

mRNA/cDNA for C2orf80 Gene

(4) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(16) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C2orf80 Gene

Chromosome 2 open reading frame 80:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C2orf80

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf80 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b
SP2: - -

Relevant External Links for C2orf80 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C2orf80 Gene

mRNA expression in normal human tissues for C2orf80 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C2orf80 Gene

This gene is overexpressed in Brain - Anterior cingulate cortex (BA24) (7.6), Brain - Frontal Cortex (BA9) (6.9), Brain - Cortex (6.7), Brain - Amygdala (6.3), Brain - Nucleus accumbens (basal ganglia) (5.7), Brain - Hippocampus (4.6), and Brain - Hypothalamus (4.1).

SOURCE GeneReport for Unigene cluster for C2orf80 Gene Hs.198416

genes like me logo Genes that share expressions with C2orf80: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for C2orf80 Gene

Orthologs for C2orf80 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C2orf80 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C2H2orf80 35
  • 88.43 (n)
  • 79.79 (a)
C2H2orf80 36
  • 78 (a)
(Mus musculus)
Mammalia D630023F18Rik 35
  • 80.08 (n)
  • 72.99 (a)
D630023F18Rik 16
D630023F18Rik 36
  • 55 (a)
(Pan troglodytes)
Mammalia C2BH2orf80 35
  • 99.48 (n)
  • 98.96 (a)
C2orf80 36
  • 98 (a)
(Canis familiaris)
Mammalia C2orf80 36
  • 86 (a)
(Monodelphis domestica)
Mammalia C2orf80 36
  • 48 (a)
(Anolis carolinensis)
Reptilia C2orf80 36
  • 58 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100489057 35
  • 63.37 (n)
  • 56.17 (a)
(Danio rerio)
Actinopterygii LOC100536292 35
  • 52.72 (n)
  • 46.81 (a)
Species with no ortholog for C2orf80:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C2orf80 Gene

Gene Tree for C2orf80 (if available)
Gene Tree for C2orf80 (if available)

Paralogs for C2orf80 Gene Pseudogenes for C2orf80 Gene

genes like me logo Genes that share paralogs with C2orf80: view

No data available for Paralogs for C2orf80 Gene

Variants for C2orf80 Gene

Sequence variations from dbSNP and Humsavar for C2orf80 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs796281 -- 208,165,854(+) CATCA(A/G)TTTAA intron-variant
rs935366 -- 208,187,663(+) GGTAC(A/T)CAGGG intron-variant
rs1348751 -- 208,170,077(+) ATTGT(C/T)ACTTG intron-variant
rs1348752 -- 208,189,349(+) CCACC(A/G)CCATT intron-variant
rs1374208 -- 208,169,991(+) CTAAG(C/T)CTCAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C2orf80 Gene

Variant ID Type Subtype PubMed ID
nsv875747 CNV Loss 21882294
nsv875748 CNV Gain 21882294
nsv834517 CNV Loss 17160897
dgv4418n71 CNV Loss 21882294
esv2721408 CNV Deletion 23290073
nsv508883 CNV Insertion 20534489
nsv524826 CNV Loss 19592680
nsv875751 CNV Gain 21882294
nsv522180 CNV Loss 19592680
esv274878 CNV Loss 21479260

Relevant External Links for C2orf80 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C2orf80 Gene

Disorders for C2orf80 Gene

Relevant External Links for C2orf80

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for C2orf80 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C2orf80 Gene

Publications for C2orf80 Gene

  1. Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. (PMID: 20080650) Xu J. … Isaacs W.B. (Proc. Natl. Acad. Sci. U.S.A. 2010) 3 48
  2. Knockdown of the psychosis susceptibility gene ZNF804A alters expression of genes involved in cell adhesion. (PMID: 22080834) Hill M.J. … Bray N.J. (Hum. Mol. Genet. 2012) 2 3
  3. Novel candidate genes for 46,XY gonadal dysgenesis identified by a customized 1 M array-CGH platform. (PMID: 24055526) Norling A. … Barbaro M. (Eur J Med Genet 2013) 2 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4

Products for C2orf80 Gene

Sources for C2orf80 Gene

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