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Aliases for C2orf78 Gene

Aliases for C2orf78 Gene

  • Chromosome 2 Open Reading Frame 78 2 3 5
  • HCG1989538 3
  • COG5373 3

External Ids for C2orf78 Gene

Previous GeneCards Identifiers for C2orf78 Gene

  • GC02P073864
  • GC02P074011

Summaries for C2orf78 Gene

GeneCards Summary for C2orf78 Gene

C2orf78 (Chromosome 2 Open Reading Frame 78) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf78 Gene

Genomics for C2orf78 Gene

Regulatory Elements for C2orf78 Gene

Enhancers for C2orf78 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C2orf78 on UCSC Golden Path with GeneCards custom track

Genomic Location for C2orf78 Gene

73,784,189 bp from pter
73,817,148 bp from pter
32,960 bases
Plus strand

Genomic View for C2orf78 Gene

Genes around C2orf78 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C2orf78 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C2orf78 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf78 Gene

Proteins for C2orf78 Gene

  • Protein details for C2orf78 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C2orf78
    Protein Accession:

    Protein attributes for C2orf78 Gene

    922 amino acids
    Molecular mass:
    100170 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C2orf78 Gene

Proteomics data for C2orf78 Gene at MOPED

Post-translational modifications for C2orf78 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C2orf78 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C2orf78 Gene

Domains & Families for C2orf78 Gene

Protein Domains for C2orf78 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C2orf78: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C2orf78 Gene

Function for C2orf78 Gene

Phenotypes for C2orf78 Gene

genes like me logo Genes that share phenotypes with C2orf78: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C2orf78 Gene

Localization for C2orf78 Gene

Subcellular locations from

Jensen Localization Image for C2orf78 Gene COMPARTMENTS Subcellular localization image for C2orf78 gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C2orf78 Gene

Pathways & Interactions for C2orf78 Gene

SuperPathways for C2orf78 Gene

No Data Available

Interacting Proteins for C2orf78 Gene

Gene Ontology (GO) - Biological Process for C2orf78 Gene


No data available for Pathways by source and SIGNOR curated interactions for C2orf78 Gene

Drugs & Compounds for C2orf78 Gene

No Compound Related Data Available

Transcripts for C2orf78 Gene

mRNA/cDNA for C2orf78 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C2orf78 Gene

Chromosome 2 open reading frame 78:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf78 Gene

No ASD Table

Relevant External Links for C2orf78 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C2orf78 Gene

mRNA expression in normal human tissues for C2orf78 Gene

mRNA differential expression in normal tissues according to GTEx for C2orf78 Gene

This gene is overexpressed in Testis (x51.5).

SOURCE GeneReport for Unigene cluster for C2orf78 Gene Hs.456833

genes like me logo Genes that share expression patterns with C2orf78: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C2orf78 Gene

Orthologs for C2orf78 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C2orf78 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C11H2orf78 35
  • 81.47 (n)
  • 68.82 (a)
C2orf78 36
  • 69 (a)
(Canis familiaris)
Mammalia C17H2orf78 35
  • 82.73 (n)
  • 73.23 (a)
C2orf78 36
  • 72 (a)
(Pan troglodytes)
Mammalia C2AH2orf78 35
  • 98.84 (n)
  • 97.61 (a)
C2orf78 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC690284 35
  • 67.29 (n)
  • 50.35 (a)
(Monodelphis domestica)
Mammalia C2orf78 36
  • 51 (a)
(Mus musculus)
Mammalia 4930433I11Rik 36
  • 45 (a)
Gm21142 36
  • 39 (a)
Gm21276 36
  • 39 (a)
Gm2128 36
  • 44 (a)
Gm4884 36
  • 45 (a)
Gm5114 36
  • 48 (a)
Gm5591 36
  • 47 (a)
Gm5592 36
  • 46 (a)
Gm6605 36
  • 43 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 31 (a)
-- 36
  • 35 (a)
Species with no ortholog for C2orf78:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C2orf78 Gene

Gene Tree for C2orf78 (if available)
Gene Tree for C2orf78 (if available)

Paralogs for C2orf78 Gene

No data available for Paralogs for C2orf78 Gene

Variants for C2orf78 Gene

Sequence variations from dbSNP and Humsavar for C2orf78 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs429646 -- 73,786,767(-) AAGAC(A/G)TACTG intron-variant
rs454444 -- 73,788,330(-) CCTTT(C/T)GTAAC intron-variant
rs2141092 -- 73,787,732(+) TGCTT(C/T)AACTC intron-variant
rs6758427 -- 73,786,248(+) ggtgg(C/T)gtgca intron-variant
rs6758624 -- 73,786,257(+) cacct(G/T)taatc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C2orf78 Gene

Variant ID Type Subtype PubMed ID
dgv1197e1 CNV Complex 17122850
essv105 CNV CNV 17122850
nsv834260 CNV Gain 17160897
nsv511053 CNV Complex 20534489
nsv2780 CNV Loss 18451855
nsv508842 CNV Insertion 20534489
nsv2781 CNV Insertion 18451855
nsv10024 CNV Gain+Loss 18304495
esv28264 CNV Gain+Loss 19812545
dgv15n31 CNV Duplication 19718026
nsv482051 CNV Gain 20164927

Variation tolerance for C2orf78 Gene

Residual Variation Intolerance Score: 35% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.22; 24.57% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C2orf78 Gene

Disorders for C2orf78 Gene

Relevant External Links for C2orf78

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C2orf78 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C2orf78 Gene

Publications for C2orf78 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 67

Products for C2orf78 Gene

Sources for C2orf78 Gene