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Aliases for C2orf73 Gene

Aliases for C2orf73 Gene

  • Chromosome 2 Open Reading Frame 73 2 3

External Ids for C2orf73 Gene

Summaries for C2orf73 Gene

GeneCards Summary for C2orf73 Gene

C2orf73 (Chromosome 2 Open Reading Frame 73) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf73 Gene

Genomics for C2orf73 Gene

Genomic Location for C2orf73 Gene

Start:
54,330,034 bp from pter
End:
54,383,742 bp from pter
Size:
53,709 bases
Orientation:
Plus strand

Genomic View for C2orf73 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C2orf73 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf73 Gene

Regulatory Elements for C2orf73 Gene

Proteins for C2orf73 Gene

  • Protein details for C2orf73 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N5S3-CB073_HUMAN
    Recommended name:
    Uncharacterized protein C2orf73
    Protein Accession:
    Q8N5S3
    Secondary Accessions:
    • A0AV79
    • A0AV81
    • Q8N7V4

    Protein attributes for C2orf73 Gene

    Size:
    287 amino acids
    Molecular mass:
    32142 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH31669.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C2orf73 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C2orf73 Gene

Proteomics data for C2orf73 Gene at MOPED

Post-translational modifications for C2orf73 Gene

No Post-translational modifications

Other Protein References for C2orf73 Gene

No data available for DME Specific Peptides for C2orf73 Gene

Domains for C2orf73 Gene

Protein Domains for C2orf73 Gene

ProtoNet:
genes like me logo Genes that share domains with C2orf73: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C2orf73 Gene

Function for C2orf73 Gene

Phenotypes for C2orf73 Gene

GenomeRNAi human phenotypes for C2orf73:
genes like me logo Genes that share phenotypes with C2orf73: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C2orf73 Gene

Localization for C2orf73 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C2orf73 Gene COMPARTMENTS Subcellular localization image for C2orf73 gene
Compartment Confidence
cytosol 3
nucleus 3

No data available for Gene Ontology (GO) - Cellular Components for C2orf73 Gene

Pathways for C2orf73 Gene

SuperPathways for C2orf73 Gene

No Data Available

Interacting Proteins for C2orf73 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000381631%0d%0a9606.ENSP00000386722%0d%0a9606.ENSP00000340237%0d%0a
Selected Interacting proteins: ENSP00000381631 Q8N5S3-CB073_HUMAN for C2orf73 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for C2orf73 Gene

None

No data available for Pathways by source for C2orf73 Gene

Transcripts for C2orf73 Gene

Unigene Clusters for C2orf73 Gene

Chromosome 2 open reading frame 73:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf73 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d
SP1:
SP2: - -
SP3: -
SP4: - -

Relevant External Links for C2orf73 Gene

GeneLoc Exon Structure for
C2orf73
ECgene alternative splicing isoforms for
C2orf73

Expression for C2orf73 Gene

mRNA expression in normal human tissues for C2orf73 Gene

mRNA differential expression in normal tissues according to GTEx for C2orf73 Gene

This gene is overexpressed in Testis (28.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C2orf73 Gene

SOURCE GeneReport for Unigene cluster for C2orf73 Gene Hs.732626

genes like me logo Genes that share expressions with C2orf73: view

Orthologs for C2orf73 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C2orf73 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C2AH2orf73 36
  • 99.07 (n)
  • 97.91 (a)
C2orf73 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C11H2orf73 36
  • 85.56 (n)
  • 76.41 (a)
C2orf73 37
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C10H2orf73 36
  • 85.33 (n)
  • 76.41 (a)
C2orf73 37
  • 48 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4930505A04Rik 36
  • 79.42 (n)
  • 68.26 (a)
4930505A04Rik 16
4930505A04Rik 37
  • 68 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C2orf73 37
  • 44 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1562229 36
  • 81.01 (n)
  • 66.96 (a)
lizard
(Anolis carolinensis)
Reptilia C2orf73 37
  • 33 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c2orf73 36
  • 61.11 (n)
  • 44.44 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 26 (a)
OneToOne
Species with no ortholog for C2orf73:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C2orf73 Gene

ENSEMBL:
Gene Tree for C2orf73 (if available)
TreeFam:
Gene Tree for C2orf73 (if available)

Paralogs for C2orf73 Gene

No data available for Paralogs for C2orf73 Gene

Variants for C2orf73 Gene

Sequence variations from dbSNP and Humsavar for C2orf73 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs13184 - 54,360,522(+) CACTA(C/G)GCACA missense, reference, intron-variant, utr-variant-3-prime
rs843667 -- 54,331,877(+) tcaca(C/T)ttgaa intron-variant
rs843668 -- 54,332,254(+) ctcct(A/G)catac intron-variant
rs843669 -- 54,332,656(+) AACCC(A/G)TAGGC intron-variant
rs843670 -- 54,335,967(+) ttaga(A/T)tgcac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C2orf73 Gene

Variant ID Type Subtype PubMed ID
esv2720078 CNV Deletion 23290073
nsv511174 CNV Loss 21212237
nsv436294 CNV Deletion 17901297
esv2604967 CNV Loss 19546169
esv2535207 CNV Deletion 19546169
nsv511786 CNV Loss 21212237
esv2276399 CNV Deletion 18987734
nsv820112 CNV Gain 19587683
esv5301 CNV Deletion 18987735
dgv631n67 CNV Loss 20364138
nsv821415 CNV Deletion 20802225
esv2720080 CNV Deletion 23290073
esv1008998 CNV Deletion 20482838
esv5705 CNV Loss 19470904
esv23352 CNV Gain 19812545

Relevant External Links for C2orf73 Gene

HapMap Linkage Disequilibrium report
C2orf73

Disorders for C2orf73 Gene

No disorders were found for C2orf73 Gene.

No data available for UniProtKB/Swiss-Prot for C2orf73 Gene

Publications for C2orf73 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. (PMID: 18654987) Thalappilly S. … Dusetti N.J. (Proteomics 2008) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C2orf73 Gene

Sources for C2orf73 Gene

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