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Aliases for C2orf72 Gene

Aliases for C2orf72 Gene

  • Chromosome 2 Open Reading Frame 72 2 3 5

External Ids for C2orf72 Gene

Previous GeneCards Identifiers for C2orf72 Gene

  • GC02P231611
  • GC02P231902
  • GC02P223744

Summaries for C2orf72 Gene

GeneCards Summary for C2orf72 Gene

C2orf72 (Chromosome 2 Open Reading Frame 72) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf72 Gene

Genomics for C2orf72 Gene

Regulatory Elements for C2orf72 Gene

Promoters for C2orf72 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C2orf72 on UCSC Golden Path with GeneCards custom track

Genomic Location for C2orf72 Gene

Chromosome:
2
Start:
231,037,490 bp from pter
End:
231,049,719 bp from pter
Size:
12,230 bases
Orientation:
Plus strand

Genomic View for C2orf72 Gene

Genes around C2orf72 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C2orf72 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C2orf72 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf72 Gene

Proteins for C2orf72 Gene

  • Protein details for C2orf72 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NCS6-CB072_HUMAN
    Recommended name:
    Uncharacterized protein C2orf72
    Protein Accession:
    A6NCS6

    Protein attributes for C2orf72 Gene

    Size:
    295 amino acids
    Molecular mass:
    30481 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C2orf72 Gene

Proteomics data for C2orf72 Gene at MOPED

Post-translational modifications for C2orf72 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C2orf72 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C2orf72 Gene

Domains & Families for C2orf72 Gene

Protein Domains for C2orf72 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C2orf72: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C2orf72 Gene

Function for C2orf72 Gene

Phenotypes for C2orf72 Gene

GenomeRNAi human phenotypes for C2orf72:
genes like me logo Genes that share phenotypes with C2orf72: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C2orf72 Gene

Localization for C2orf72 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C2orf72 Gene COMPARTMENTS Subcellular localization image for C2orf72 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C2orf72 Gene

Pathways & Interactions for C2orf72 Gene

SuperPathways for C2orf72 Gene

No Data Available

Interacting Proteins for C2orf72 Gene

Gene Ontology (GO) - Biological Process for C2orf72 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C2orf72 Gene

Drugs & Compounds for C2orf72 Gene

No Compound Related Data Available

Transcripts for C2orf72 Gene

mRNA/cDNA for C2orf72 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C2orf72 Gene

Chromosome 2 open reading frame 72:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf72 Gene

No ASD Table

Relevant External Links for C2orf72 Gene

GeneLoc Exon Structure for
C2orf72
ECgene alternative splicing isoforms for
C2orf72

Expression for C2orf72 Gene

mRNA expression in normal human tissues for C2orf72 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C2orf72 Gene

This gene is overexpressed in Liver (x12.2).

Protein differential expression in normal tissues from HIPED for C2orf72 Gene

This gene is overexpressed in Nasal epithelium (52.7) and Adipocyte (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C2orf72 Gene



SOURCE GeneReport for Unigene cluster for C2orf72 Gene Hs.526596

genes like me logo Genes that share expression patterns with C2orf72: view

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C2orf72 Gene

Orthologs for C2orf72 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C2orf72 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C2BH2orf72 35
  • 97.7 (n)
  • 96.55 (a)
C2orf72 36
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C2orf72 36
  • 79 (a)
OneToOne
C2H2orf72 35
  • 84.21 (n)
  • 78.6 (a)
dog
(Canis familiaris)
Mammalia C25H2orf72 35
  • 86.79 (n)
  • 81.79 (a)
C2orf72 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2810459M11Rik 36
  • 71 (a)
OneToOne
2810459M11Rik 16
2810459M11Rik 35
  • 78.05 (n)
  • 70.03 (a)
rat
(Rattus norvegicus)
Mammalia LOC100362216 35
  • 78.63 (n)
  • 72.13 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100498583 35
  • 50.38 (n)
  • 41.22 (a)
Species with no ortholog for C2orf72:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C2orf72 Gene

ENSEMBL:
Gene Tree for C2orf72 (if available)
TreeFam:
Gene Tree for C2orf72 (if available)

Paralogs for C2orf72 Gene

No data available for Paralogs for C2orf72 Gene

Variants for C2orf72 Gene

Sequence variations from dbSNP and Humsavar for C2orf72 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs6854 -- 231,048,680(+) GGATG(G/T)TGTGA utr-variant-3-prime
rs889958 -- 231,039,618(-) ACCCT(A/G)AGGGA intron-variant
rs866407 -- 231,045,292(+) atata(G/T)agaga intron-variant
rs2052625 -- 231,041,140(-) GGGTG(G/T)GTTTT intron-variant
rs2279999 -- 231,041,171(+) GTGTT(G/T)TTAAT intron-variant

Variation tolerance for C2orf72 Gene

Gene Damage Index Score: 6.89; 79.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C2orf72 Gene

HapMap Linkage Disequilibrium report
C2orf72

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C2orf72 Gene

Disorders for C2orf72 Gene

Relevant External Links for C2orf72

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C2orf72

No disorders were found for C2orf72 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C2orf72 Gene

Publications for C2orf72 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 67
  2. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3
  3. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. (PMID: 11752456) Xu X.R. … Han Z.G. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3

Products for C2orf72 Gene

Sources for C2orf72 Gene

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