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Aliases for C2orf70 Gene

Aliases for C2orf70 Gene

  • Chromosome 2 Open Reading Frame 70 2 3
  • Hypothetical Protein LOC339778 2

External Ids for C2orf70 Gene

Previous GeneCards Identifiers for C2orf70 Gene

  • GC02P026638
  • GC02P026785

Summaries for C2orf70 Gene

GeneCards Summary for C2orf70 Gene

C2orf70 (Chromosome 2 Open Reading Frame 70) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf70 Gene

Genomics for C2orf70 Gene

Regulatory Elements for C2orf70 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C2orf70 Gene

26,562,559 bp from pter
26,579,532 bp from pter
16,974 bases
Plus strand

Genomic View for C2orf70 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C2orf70 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf70 Gene

Proteins for C2orf70 Gene

  • Protein details for C2orf70 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0573 protein C2orf70
    Protein Accession:
    Secondary Accessions:

    Protein attributes for C2orf70 Gene

    201 amino acids
    Molecular mass:
    23421 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C2orf70 Gene

Proteomics data for C2orf70 Gene at MOPED

Post-translational modifications for C2orf70 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C2orf70 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C2orf70 Gene

Domains for C2orf70 Gene

Protein Domains for C2orf70 Gene


Suggested Antigen Peptide Sequences for C2orf70 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0573 family.
  • Belongs to the UPF0573 family.
genes like me logo Genes that share domains with C2orf70: view

No data available for Gene Families for C2orf70 Gene

Function for C2orf70 Gene

Phenotypes for C2orf70 Gene

genes like me logo Genes that share phenotypes with C2orf70: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C2orf70 Gene

Localization for C2orf70 Gene

Subcellular locations from

Jensen Localization Image for C2orf70 Gene COMPARTMENTS Subcellular localization image for C2orf70 gene
Compartment Confidence
nucleus 3
cytosol 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C2orf70 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 21630459
genes like me logo Genes that share ontologies with C2orf70: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C2orf70 Gene

Pathways for C2orf70 Gene

SuperPathways for C2orf70 Gene

No Data Available

Interacting Proteins for C2orf70 Gene

Gene Ontology (GO) - Biological Process for C2orf70 Gene


No data available for Pathways by source for C2orf70 Gene

Transcripts for C2orf70 Gene

Unigene Clusters for C2orf70 Gene

Chromosome 2 open reading frame 70:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C2orf70

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf70 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6
SP1: - -
SP2: -

Relevant External Links for C2orf70 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C2orf70 Gene

mRNA expression in normal human tissues for C2orf70 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C2orf70 Gene

This gene is overexpressed in Testis (27.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C2orf70 Gene

SOURCE GeneReport for Unigene cluster for C2orf70 Gene Hs.407083

genes like me logo Genes that share expressions with C2orf70: view

Expression partners for C2orf70 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C2orf70 Gene

Orthologs for C2orf70 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C2orf70 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C11H2orf70 35
  • 83.91 (n)
  • 78.61 (a)
C11H2orf70 36
  • 79 (a)
(Canis familiaris)
Mammalia C17H2orf70 35
  • 84.58 (n)
  • 78.11 (a)
C2orf70 36
  • 78 (a)
(Mus musculus)
Mammalia 1700001C02Rik 35
  • 77 (n)
  • 68.5 (a)
1700001C02Rik 16
1700001C02Rik 36
  • 69 (a)
(Pan troglodytes)
Mammalia C2AH2orf70 35
  • 97.25 (n)
  • 96.15 (a)
C2orf70 36
  • 90 (a)
(Rattus norvegicus)
Mammalia RGD1559683 35
  • 76.33 (n)
  • 67.5 (a)
(Monodelphis domestica)
Mammalia C2orf70 36
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia C2orf70 36
  • 60 (a)
(Gallus gallus)
Aves C3H2ORF70 35
  • 64.47 (n)
  • 58.49 (a)
C2orf70 36
  • 54 (a)
(Anolis carolinensis)
Reptilia C2orf70 36
  • 61 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c2orf70 35
  • 62.25 (n)
  • 50.99 (a)
(Danio rerio)
Actinopterygii si:ch211-198b3.4 35
  • 53.79 (n)
  • 43.18 (a)
C20H2orf70 36
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 43 (a)
Species with no ortholog for C2orf70:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C2orf70 Gene

Gene Tree for C2orf70 (if available)
Gene Tree for C2orf70 (if available)

Paralogs for C2orf70 Gene

No data available for Paralogs for C2orf70 Gene

Variants for C2orf70 Gene

Sequence variations from dbSNP and Humsavar for C2orf70 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs751651 -- 26,569,228(-) CATCC(G/T)CCATC intron-variant
rs751652 -- 26,569,266(-) TTCTG(A/G)CAACT intron-variant
rs935170 -- 26,569,167(+) GATGG(A/G)CCTCA intron-variant
rs939815 -- 26,568,586(+) TGTCA(A/C)TTCCA intron-variant
rs1053807 -- 26,577,554(+) AAGAC(A/G)GGCAC synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for C2orf70 Gene

Variant ID Type Subtype PubMed ID
esv33316 CNV Loss 17666407
nsv517800 CNV Loss 19592680

Relevant External Links for C2orf70 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C2orf70 Gene

Disorders for C2orf70 Gene

No disorders were found for C2orf70 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C2orf70 Gene

Publications for C2orf70 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  2. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4

Products for C2orf70 Gene

Sources for C2orf70 Gene

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