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Aliases for C2orf68 Gene

Aliases for C2orf68 Gene

  • Chromosome 2 Open Reading Frame 68 2 3
  • UPF0561 Protein C2orf68 3
  • HCRCN81 3

External Ids for C2orf68 Gene

Previous GeneCards Identifiers for C2orf68 Gene

  • GC02M085688
  • GC02M085832
  • GC02M085729

Summaries for C2orf68 Gene

GeneCards Summary for C2orf68 Gene

C2orf68 (Chromosome 2 Open Reading Frame 68) is a Protein Coding gene. Diseases associated with C2orf68 include colorectal adenocarcinoma.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf68 Gene

Genomics for C2orf68 Gene

Regulatory Elements for C2orf68 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C2orf68 Gene

Start:
85,605,253 bp from pter
End:
85,612,066 bp from pter
Size:
6,814 bases
Orientation:
Minus strand

Genomic View for C2orf68 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C2orf68 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf68 Gene

Proteins for C2orf68 Gene

  • Protein details for C2orf68 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2NKX9-CB068_HUMAN
    Recommended name:
    UPF0561 protein C2orf68
    Protein Accession:
    Q2NKX9
    Secondary Accessions:
    • B4DT10
    • Q4G0J7
    • Q6ZVA6

    Protein attributes for C2orf68 Gene

    Size:
    166 amino acids
    Molecular mass:
    18751 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C2orf68 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C2orf68 Gene

Proteomics data for C2orf68 Gene at MOPED

Post-translational modifications for C2orf68 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C2orf68 Gene

No data available for DME Specific Peptides for C2orf68 Gene

Domains for C2orf68 Gene

Protein Domains for C2orf68 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C2orf68 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q2NKX9

UniProtKB/Swiss-Prot:

CB068_HUMAN :
  • Q2NKX9
Family:
  • Belongs to the UPF0561 family.
genes like me logo Genes that share domains with C2orf68: view

No data available for Gene Families for C2orf68 Gene

Function for C2orf68 Gene

Phenotypes for C2orf68 Gene

GenomeRNAi human phenotypes for C2orf68:
genes like me logo Genes that share phenotypes with C2orf68: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C2orf68

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C2orf68 Gene

Localization for C2orf68 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C2orf68 Gene COMPARTMENTS Subcellular localization image for C2orf68 gene
Compartment Confidence
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C2orf68 Gene

Pathways for C2orf68 Gene

SuperPathways for C2orf68 Gene

No Data Available

Interacting Proteins for C2orf68 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000304410%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000304410 for C2orf68 Gene via STRING

Symbol External ID(s) Details
ELAVL1

Gene Ontology (GO) - Biological Process for C2orf68 Gene

None

No data available for Pathways by source for C2orf68 Gene

Transcripts for C2orf68 Gene

Unigene Clusters for C2orf68 Gene

Chromosome 2 open reading frame 68:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C2orf68

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C2orf68

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf68 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b
SP1: - - - - -
SP2: - - - - -
SP3: -
SP4: -
SP5: -

Relevant External Links for C2orf68 Gene

GeneLoc Exon Structure for
C2orf68
ECgene alternative splicing isoforms for
C2orf68

Expression for C2orf68 Gene

mRNA expression in normal human tissues for C2orf68 Gene

SOURCE GeneReport for Unigene cluster for C2orf68 Gene Hs.516159

genes like me logo Genes that share expressions with C2orf68: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for C2orf68 Gene

Orthologs for C2orf68 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C2orf68 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C2AH2orf68 35
  • 99.4 (n)
  • 98.19 (a)
C2orf68 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C11H2orf68 35
  • 88.62 (n)
  • 86.51 (a)
C2orf68 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C17H2orf68 35
  • 90.36 (n)
  • 89.16 (a)
C2orf68 36
  • 61 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 0610030E20Rik 35
  • 85.34 (n)
  • 83.13 (a)
0610030E20Rik 16
0610030E20Rik 36
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C2orf68 36
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC691113 35
  • 87.55 (n)
  • 86.75 (a)
lizard
(Anolis carolinensis)
Reptilia C2orf68 36
  • 58 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.19302 35
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495513 35
  • 64.01 (n)
  • 64.49 (a)
zebrafish
(Danio rerio)
Actinopterygii C5H2orf68 36
  • 51 (a)
OneToOne
si:ch211-283h6.4 35
  • 59.13 (n)
  • 54.79 (a)
Species with no ortholog for C2orf68:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C2orf68 Gene

ENSEMBL:
Gene Tree for C2orf68 (if available)
TreeFam:
Gene Tree for C2orf68 (if available)

Paralogs for C2orf68 Gene

Selected SIMAP similar genes for C2orf68 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with C2orf68: view

No data available for Paralogs for C2orf68 Gene

Variants for C2orf68 Gene

Structural Variations from Database of Genomic Variants (DGV) for C2orf68 Gene

Variant ID Type Subtype PubMed ID
dgv4202n71 CNV Loss 21882294

Relevant External Links for C2orf68 Gene

HapMap Linkage Disequilibrium report
C2orf68

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for C2orf68 Gene

Disorders for C2orf68 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for C2orf68 Gene including...

Search for C2orf68 Gene in MalaCards »
genes like me logo Genes that share disorders with C2orf68: view

No data available for UniProtKB/Swiss-Prot for C2orf68 Gene

Publications for C2orf68 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The role of c2orf68 and PI3K/Akt/mTOR pathway in human colorectal cancer. (PMID: 25023051) Wen X. … Chen Y. (Med. Oncol. 2014) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3

Products for C2orf68 Gene

Sources for C2orf68 Gene

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