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Aliases for C2orf42 Gene

Aliases for C2orf42 Gene

  • Chromosome 2 Open Reading Frame 42 2 3

External Ids for C2orf42 Gene

Previous GeneCards Identifiers for C2orf42 Gene

  • GC02M070230
  • GC02M070377
  • GC02M070113

Summaries for C2orf42 Gene

GeneCards Summary for C2orf42 Gene

C2orf42 (Chromosome 2 Open Reading Frame 42) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf42 Gene

Genomics for C2orf42 Gene

Regulatory Elements for C2orf42 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C2orf42 Gene

70,149,880 bp from pter
70,248,615 bp from pter
98,736 bases
Minus strand

Genomic View for C2orf42 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C2orf42 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf42 Gene

Proteins for C2orf42 Gene

  • Protein details for C2orf42 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C2orf42
    Protein Accession:
    Secondary Accessions:
    • D6W5G3
    • Q9H629

    Protein attributes for C2orf42 Gene

    574 amino acids
    Molecular mass:
    64077 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C2orf42 Gene

Proteomics data for C2orf42 Gene at MOPED

Post-translational modifications for C2orf42 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C2orf42 Gene

Domains for C2orf42 Gene

Protein Domains for C2orf42 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C2orf42: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C2orf42 Gene

Function for C2orf42 Gene

Gene Ontology (GO) - Molecular Function for C2orf42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C2orf42: view

Phenotypes for C2orf42 Gene

GenomeRNAi human phenotypes for C2orf42:
genes like me logo Genes that share phenotypes with C2orf42: view

Animal Model Products

CRISPR Products

miRNA for C2orf42 Gene

miRTarBase miRNAs that target C2orf42

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for C2orf42 Gene

Localization for C2orf42 Gene

Subcellular locations from

Jensen Localization Image for C2orf42 Gene COMPARTMENTS Subcellular localization image for C2orf42 gene
Compartment Confidence
cytosol 2
nucleus 2

Gene Ontology (GO) - Cellular Components for C2orf42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0031965 nuclear membrane IDA --
genes like me logo Genes that share ontologies with C2orf42: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C2orf42 Gene

Pathways for C2orf42 Gene

SuperPathways for C2orf42 Gene

No Data Available

Interacting Proteins for C2orf42 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000264434 Q9NWW7-CB042_HUMAN for C2orf42 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for C2orf42 Gene


No data available for Pathways by source for C2orf42 Gene

Transcripts for C2orf42 Gene

Unigene Clusters for C2orf42 Gene

Chromosome 2 open reading frame 42:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C2orf42

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf42 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d · 8e · 8f · 8g · 8h ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^
SP1: - - - - - - - -
SP2: - - - - - -
SP3: - - - - - -
SP4: - - - - - - -
SP5: - - -
SP6: - -
SP7: - - - -
SP8: -
SP9: - - - - - - - - - -
SP10: - - - - - - - -
SP11: -

ExUns: 14 ^ 15

Relevant External Links for C2orf42 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C2orf42 Gene

mRNA expression in normal human tissues for C2orf42 Gene

mRNA differential expression in normal tissues according to GTEx for C2orf42 Gene

This gene is overexpressed in Testis (5.3).

Protein differential expression in normal tissues for C2orf42 Gene

This gene is overexpressed in Adrenal (32.7), Colon (19.1), and Testis (11.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C2orf42 Gene

SOURCE GeneReport for Unigene cluster for C2orf42 Gene Hs.720049

genes like me logo Genes that share expressions with C2orf42: view

Expression partners for C2orf42 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C2orf42 Gene

Orthologs for C2orf42 Gene

This gene was present in the common ancestor of animals.

Orthologs for C2orf42 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C11H2orf42 35
  • 92.86 (n)
  • 97.56 (a)
C2orf42 36
  • 98 (a)
(Canis familiaris)
Mammalia C10H2orf42 35
  • 92.16 (n)
  • 96.17 (a)
C2ORF42 36
  • 96 (a)
(Mus musculus)
Mammalia C87436 35
  • 87.22 (n)
  • 91.64 (a)
C87436 16
C87436 36
  • 92 (a)
(Pan troglodytes)
Mammalia C2AH2orf42 35
  • 99.76 (n)
  • 100 (a)
C2ORF42 36
  • 100 (a)
(Rattus norvegicus)
Mammalia RGD1306746 35
  • 88.15 (n)
  • 92.51 (a)
(Monodelphis domestica)
Mammalia C2orf42 36
  • 92 (a)
(Gallus gallus)
Aves C22H2ORF42 35
  • 74.44 (n)
  • 83.51 (a)
C22H2ORF42 36
  • 80 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c2orf42 35
  • 68.02 (n)
  • 70.6 (a)
Str.15817 35
(Danio rerio)
Actinopterygii si:ch211-127d4.3 35
  • 57.24 (n)
  • 56.17 (a)
C5H2orf42 36
  • 52 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001614 35
  • 39.43 (n)
  • 31.83 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG2321 36
  • 20 (a)
Species with no ortholog for C2orf42:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C2orf42 Gene

Gene Tree for C2orf42 (if available)
Gene Tree for C2orf42 (if available)

Paralogs for C2orf42 Gene

No data available for Paralogs for C2orf42 Gene

Variants for C2orf42 Gene

Sequence variations from dbSNP and Humsavar for C2orf42 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs14691 -- 70,150,177(+) CAAAA(A/G)GGCTA utr-variant-3-prime, downstream-variant-500B
rs1562295 -- 70,159,326(+) CTCAC(A/G)CCTGT intron-variant
rs3213941 - 70,175,771(+) TCATC(G/T)GTGCA reference, missense, nc-transcript-variant
rs3732260 -- 70,150,323(+) GCAAA(A/T)TAAGC utr-variant-3-prime, nc-transcript-variant
rs3821274 -- 70,181,806(+) TCAAC(A/G)CTAGG synonymous-codon, reference, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for C2orf42 Gene

Variant ID Type Subtype PubMed ID
nsv518294 CNV Loss 19592680
esv2671105 CNV Deletion 23128226

Relevant External Links for C2orf42 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C2orf42 Gene

Disorders for C2orf42 Gene

No disorders were found for C2orf42 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C2orf42 Gene

Publications for C2orf42 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PMID: 22990118) Woods N.T. … Monteiro A.N. (Sci Signal 2012) 3
  3. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  4. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for C2orf42 Gene

Sources for C2orf42 Gene

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