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C2orf40 Gene

protein-coding   GIFtS: 44
GCID: GC02P106679

Chromosome 2 Open Reading Frame 40

  See C2orf40-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Chromosome 2 Open Reading Frame 401 2
ECRG42 3 5
Esophageal Cancer Related Gene 4 Protein1 2
Esophageal Cancer-Related Gene 4 Protein2 3
augurin2

External Ids:    HGNC: 246421   Entrez Gene: 844172   Ensembl: ENSG000001191477   OMIM: 6117525   UniProtKB: Q9H1Z83   
ORGUL members:         

Export aliases for C2orf40 gene to outside databases

Previous GC identifers: GC02P106048 GC02P100451


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for C2orf40 Gene:
C2orf40 (chromosome 2 open reading frame 40) is a protein-coding gene. Diseases associated with C2orf40 include esophageal cancer, and esophageal squamous cell carcinoma.

UniProtKB/Swiss-Prot: AUGN_HUMAN, Q9H1Z8
Function: Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized
by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the C2orf40 gene promoter:
         E2F-3a   E2F-4   E2F-5   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   E2F-2   POU3F2   HNF-1A   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidC2orf40 promoter sequence
   Search Chromatin IP Primers for C2orf40

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C2orf40


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q12.2   Ensembl cytogenetic band:  2q12.2   HGNC cytogenetic band: 2q12.2

C2orf40 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C2orf40 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P106679:  view genomic region     (about GC identifiers)

Start:
106,679,702 bp from pter      End:
106,694,615 bp from pter
Size:
14,914 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: AUGN_HUMAN, Q9H1Z8 (See protein sequence)
Recommended Name: Augurin precursor  
Size: 148 amino acids; 17183 Da
Secondary accessions: D3DVK2

Explore the universe of human proteins at neXtProt for C2orf40: NX_Q9H1Z8

Explore proteomics data for C2orf40 at MOPED


See C2orf40 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_115787.1  
ENSEMBL proteins: 
 ENSP00000386421   ENSP00000238044   ENSP00000388664  

C2orf40 Human Recombinant Protein Products:

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LSBio Antibodies in human, mouse, rat for C2orf40

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Search eBioscience for ELISAs for C2orf40 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR028173 Augurin

Graphical View of Domain Structure for InterPro Entry Q9H1Z8

ProtoNet protein and cluster: Q9H1Z8

UniProtKB/Swiss-Prot: AUGN_HUMAN, Q9H1Z8
Similarity: Belongs to the augurin family


Find genes that share domains with C2orf40           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: AUGN_HUMAN, Q9H1Z8
Function: Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized
by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity)

Phenotypes:
     1 MGI phenotypic allele for 1500015O10Rik (no phenotypes)


Find genes that share phenotypes with C2orf40           About GenesLikeMe

Animal Models:
     MGI mouse knock-out 1500015O10Riktm1Lex for C2orf40

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C2orf40
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for C2orf40

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C2orf40
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C2orf40

miRNA
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Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat C2orf40

Gene Editing
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OriGene clones in human, mouse for C2orf40 (see all 7)
OriGene ORF clones in mouse, rat for C2orf40
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GenScript: all cDNA clones in your preferred vector: C2orf40 (NM_032411)
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for C2orf40
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf40

Cell Line
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf40


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
AUGN_HUMAN, Q9H1Z8: Secreted. Cytoplasmic vesicle, secretory vesicle
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5
cytosol1
endoplasmic reticulum1
golgi apparatus1
nucleus1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005615extracellular space IEA--
GO:0030133transport vesicle IEA--

Find genes that share ontologies with C2orf40           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for C2orf40
Interactions:

    Search GeneGlobe Interaction Network for C2orf40

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for C2orf40 (ENSP000002380444) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
TP53ENSP000002693054STRING: ENSP00000269305
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Gene Ontology (GO): 3 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008054cyclin catabolic process IEA--
GO:0070314G1 to G0 transition IEA--
GO:0090398cellular senescence IEA--

Find genes that share ontologies with C2orf40           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for C2orf40 (AUGN)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for C2orf40 gene: 
NM_032411.2  

Unigene Cluster for C2orf40:

Chromosome 2 open reading frame 40
Hs.43125  [show with all ESTs]
Unigene Representative Sequence: BQ722016
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000493478 ENST00000489174 ENST00000409944 ENST00000238044(uc010fjf.3)
ENST00000437659 ENST00000479337
miRNA
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Inhib. RNA
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OriGene RNAi products in human, mouse, rat for C2orf40
Predesigned siRNA for gene silencing in human, mouse, rat C2orf40
Clone
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OriGene ORF clones in mouse, rat for C2orf40
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: C2orf40 (NM_032411)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for C2orf40
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf40
Primer
Products:
    
OriGene qPCR primer pairs and template standards for C2orf40
OriGene qSTAR qPCR primer pairs in human, mouse for C2orf40
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat C2orf40
  QuantiTect SYBR Green Assays in human, mouse, rat C2orf40
  QuantiFast Probe-based Assays in human, mouse, rat C2orf40

Additional mRNA sequence: 

AF325503.1 AY358601.1 BC021742.1 

5 DOTS entries:

DT.95078761  DT.100816270  DT.100816271  DT.120940508  DT.95157831 

Selected AceView cDNA sequences (see all 92):

CA418648 BQ181263 BQ181838 U77056 AI811018 AW271502 AI984927 AA689224 
BQ181780 BQ182570 AI446209 AI401806 BG928916 AI208884 BQ183287 AI185817 
AA443800 AI480082 AW294454 AA689501 AI671498 AI422974 BQ017139 AI636068 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for C2orf40    About this scheme

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c
SP1:                                      -           -                     
SP2:                          -           -           -                     
SP3:              -     -     -           -           -                     
SP4:              -     -     -           -                                 
SP5:                                                  -                     


ECgene alternative splicing isoforms for C2orf40

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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C2orf40 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGAATGCCTC
C2orf40 Expression
About this image


C2orf40 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 9) fully expand
 
 Lung (Respiratory System)
         Trachea
 
 Heart (Cardiovascular System)
         Atrioventricular Node Cells Atrioventricular Node
 
 Testis (Reproductive System)
         Sertoli cells Seminiferous Tubules
 
 Epiblast (Early Embryonic Tissues)
         Epiblast-like cells
 
 Bone (Muscoskeletal System)
         Zeugopod Epiphyseal End
C2orf40 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

C2orf40 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.43125
    Custom PCR Arrays for C2orf40
Primer
Products:
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QuantiFast Probe-based Assays in human, mouse, rat C2orf40
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf40

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for C2orf40 gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia 1500015O10Rik1 , 5 RIKEN cDNA 1500015O10 gene1, 5 81.53(n)1
83.78(a)1
  1 (23.44 cM)5
788961  NM_024283.31  NP_077245.21 
 437306025 
chicken
(Gallus gallus)
Aves C1H2ORF401 chromosome 1 open reading frame, human C2orf40 73.81(n)
69.05(a)
  771055  XM_004938515.1  XP_004938572.1 
lizard
(Anolis carolinensis)
Reptilia C2orf406
chromosome 2 open reading frame 40
63(a)
1 ↔ 1
3(108516913-108523288)
African clawed frog
(Xenopus laevis)
Amphibia ecrg4-A2 esophageal cancer related gene 4 protein 74.92(n)    BC044044.1 
zebrafish
(Danio rerio)
Actinopterygii ecrg4a1 esophageal cancer related gene 4a 59.13(n)
55.65(a)
  791762  NM_001017697.1  NP_001017697.1 


ENSEMBL Gene Tree for C2orf40 (if available)
TreeFam Gene Tree for C2orf40 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for C2orf40 (see all 438)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 2 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1388192731,2
--100449535(+) ACTCTC/TTGGTC 1 -- us2k10--------
rs48519121,2
C,F,A,H--100449538(+) CTCTGA/GTCATA 1 -- us2k116Minor allele frequency- G:0.02NS EA NA WA CSA 792
rs1431468391,2
--100449543(+) GTCATA/GTCCCG 1 -- us2k10--------
rs1847026651,2
--100449564(+) GATAAC/TTTATT 1 -- us2k10--------
rs1474776011,2
C--100449589(+) GTCTCA/GCTTTG 1 -- us2k10--------
rs1405561081,2
C--100449618(+) AGTGGC/TGCAAT 1 -- us2k10--------
rs1386866641,2
--100449619(+) GTGGCA/GCAATC 1 -- us2k10--------
rs1900226571,2
--106680176(+) TGGAAC/GTACAG 1 -- us2k10--------
rs1116653621,2
C,F--106680177(+) GGAACC/TACAGG 1 -- us2k11Minor allele frequency- T:0.50CSA 2
rs1807751611,2
--106680263(+) AAACTA/CCTGAC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for C2orf40 (106679702 - 106694615 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for C2orf40: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing C2orf40
DNA2.0 Custom Variant and Variant Library Synthesis for C2orf40

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 611752    OMIM disorders: --

2 diseases for C2orf40:    
About MalaCards
esophageal cancer    esophageal squamous cell carcinoma

1 disease from the University of Copenhagen DISEASES database for C2orf40:
Esophageal cancer

Find genes that share disorders with C2orf40           About GenesLikeMe


Export disorders for C2orf40 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for C2orf40 gene, integrated from 10 sources (see all 24):
(articles sorted by number of sources associating them with C2orf40)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Expression of ECRG4, a novel esophageal cancer-related gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma. (PubMed id 12800218)1, 3, 9 Yue C.M....Lu S.H. (World J. Gastroenterol. 2003)
  2. Identification of novel peptide hormones in the human proteome by hidden Markov model screening. (PubMed id 17284679)1, 2 Mirabeau O.... Gross C. (Genome Res. 2007)
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
  6. Overexpression of ECRG4 enhances chemosensitivity to 5-fluorouracil in the human gastric cancer SGC-7901 cell line. (PubMed id 23553029)1 Jiang C.P....Liu F. (Tumour Biol. 2013)
  7. C2ORF40 suppresses breast cancer cell proliferation and invasion through modulating expression of M phase cell cycle genes. (PubMed id 23770814)1 Lu J....Wei G. (Epigenetics 2013)
  8. Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease. (PubMed id 24058526)1 Bhatnagar P....Arking D.E. (PLoS ONE 2013)
  9. Promoter methylation of esophageal cancer-related gene 4 in gastric cancer tissue and its clinical significance. (PubMed id 22626786)1 Wang Y.B. and Ba C.F. (Hepatogastroenterology 2012)
  10. ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells. (PubMed id 22411956)1 Matsuzaki J....Sato N. (Carcinogenesis 2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 84417 HGNC: 24642 AceView: ECRG4 Ensembl:ENSG00000119147 euGenes: HUgn84417
ECgene: C2orf40 H-InvDB: C2orf40

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for C2orf40 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for C2orf40 gene:
Search GeneIP for patents involving C2orf40

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
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 OriGene Antibodies for C2orf40   OriGene RNAi products in human, mouse, rat for C2orf40  
 OriGene qPCR primer pairs and template standards for C2orf40   OriGene Protein Over-expression Lysate for C2orf40  
 OriGene MassSpec something-or-other for C2orf40   OriGene clones in human, mouse for C2orf40  
 OriGene qSTAR qPCR primer pairs in human, mouse for C2orf40   OriGene Purified Protein for C2orf40  
 OriGene ORF clones in mouse, rat for C2orf40   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for C2orf40   OriGene Custom Protein Services for C2orf40  

 
 
 Block miRNA regulation of human, mouse, rat C2orf40 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing C2orf40
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C2orf40 Predesigned siRNA for gene silencing in human, mouse, rat C2orf40
 QuantiFast Probe-based Assays in human, mouse, rat C2orf40 QuantiTect SYBR Green Assays in human, mouse, rat C2orf40
 Custom PCR Arrays for C2orf40 Search Chromatin IP Primers for C2orf40
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat C2orf40  Search GeneGlobe Interaction Network for C2orf40
 Regulatory tfbs in C2orf40 promoter
 GenScript Custom Purified and Recombinant Proteins Services for C2orf40 GenScript cDNA clones with any tag delivered in your preferred vector for C2orf40
 GenScript Custom Assay Services for C2orf40 GenScript Custom overexpressing Cell Line Services for C2orf40
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
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 Search Tocris compounds for C2orf40 (AUGN)
 Browse Sino Biological Proteins
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 Protein Production Services
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 C2orf40 antibodies
 C2orf40 lysates
 Antibodies for C2orf40
 See all of Abcam's Antibodies, Kits and Proteins for C2orf40
 Custom Antibody / Protein Production Service
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 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.



 Browse ESI BIO Cell Lines and PureStem Progenitors for C2orf40
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf40
 SwitchGear 3'UTR luciferase reporter plasmids for C2orf40
 SwitchGear Promoter luciferase reporter plasmids for C2orf40
 Search ThermoFisher Antibodies for C2orf40
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf40
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C2orf40
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for C2orf40
 LSBio Antibodies in human, mouse, rat for C2orf40
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for C2orf40
  Search eBioscience for proteins for C2orf40
  Search eBioscience for elisas for C2orf40
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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