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Aliases for C2orf27B Gene

Aliases for C2orf27B Gene

  • Chromosome 2 Open Reading Frame 27B 2 3
  • C2orf27A C2orf27B 4

External Ids for C2orf27B Gene

Previous GeneCards Identifiers for C2orf27B Gene

  • GC02M132270
  • GC02M132552
  • GC02M124546

Summaries for C2orf27B Gene

GeneCards Summary for C2orf27B Gene

C2orf27B (Chromosome 2 Open Reading Frame 27B) is a Protein Coding gene. An important paralog of this gene is C2orf27A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf27B Gene

Genomics for C2orf27B Gene

Genomic Location for C2orf27B Gene

Start:
131,794,961 bp from pter
End:
131,801,661 bp from pter
Size:
6,701 bases
Orientation:
Minus strand

Genomic View for C2orf27B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C2orf27B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf27B Gene

No data available for Regulatory Elements for C2orf27B Gene

Proteins for C2orf27B Gene

  • Protein details for C2orf27B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q580R0-CB027_HUMAN
    Recommended name:
    Uncharacterized protein C2orf27
    Protein Accession:
    Q580R0
    Secondary Accessions:
    • O43575
    • Q2M1X0
    • Q52M10
    • Q86XG2

    Protein attributes for C2orf27B Gene

    Size:
    203 amino acids
    Molecular mass:
    21517 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C2orf27B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C2orf27B Gene

Proteomics data for C2orf27B Gene at MOPED

Post-translational modifications for C2orf27B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C2orf27B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C2orf27B Gene

Domains for C2orf27B Gene

Protein Domains for C2orf27B Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C2orf27B: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C2orf27B Gene

Function for C2orf27B Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C2orf27B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C2orf27B Gene

Localization for C2orf27B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C2orf27B Gene COMPARTMENTS Subcellular localization image for C2orf27B gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C2orf27B Gene

Pathways for C2orf27B Gene

SuperPathways for C2orf27B Gene

No Data Available

Interacting Proteins for C2orf27B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000304065%0d%0a9606.ENSP00000244769%0d%0a
Selected Interacting proteins: ENSP00000304065 for C2orf27B Gene via STRING

Symbol External ID(s) Details
ATXN1

Gene Ontology (GO) - Biological Process for C2orf27B Gene

None

No data available for Pathways by source for C2orf27B Gene

Transcripts for C2orf27B Gene

mRNA/cDNA for C2orf27B Gene

(20) Selected AceView cDNA sequences:
(1) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C2orf27B Gene

Chromosome 2 open reading frame 27B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C2orf27B

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C2orf27B
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf27B Gene

No ASD Table

Relevant External Links for C2orf27B Gene

GeneLoc Exon Structure for
C2orf27B
ECgene alternative splicing isoforms for
C2orf27B

Expression for C2orf27B Gene

mRNA expression in normal human tissues for C2orf27B Gene

mRNA differential expression in normal tissues according to GTEx for C2orf27B Gene

This gene is overexpressed in Pancreas (33.5) and Spleen (4.9).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C2orf27B Gene

SOURCE GeneReport for Unigene cluster for C2orf27B Gene Hs.145567

genes like me logo Genes that share expressions with C2orf27B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C2orf27B Gene

Orthologs for C2orf27B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C2orf27B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 92 (a)
OneToMany
LOC749466 35
  • 97.53 (n)
  • 94.44 (a)
Species with no ortholog for C2orf27B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C2orf27B Gene

ENSEMBL:
Gene Tree for C2orf27B (if available)
TreeFam:
Gene Tree for C2orf27B (if available)

Paralogs for C2orf27B Gene

Paralogs for C2orf27B Gene

Pseudogenes.org Pseudogenes for C2orf27B Gene

genes like me logo Genes that share paralogs with C2orf27B: view

Variants for C2orf27B Gene

Sequence variations from dbSNP and Humsavar for C2orf27B Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs892973 -- 131,796,360(+) caatt(A/C)tcctg intron-variant
rs1056216 -- 131,795,311(+) TGGGG(C/G/T)TGTTT missense, reference
rs1808776 -- 131,796,370(+) GCCTC(A/C/T)GTCTC intron-variant
rs1975263 -- 131,798,699(-) CCTAG(A/G)ATCTG intron-variant
rs2002567 -- 131,798,003(+) TCAAT(C/T)TGGGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C2orf27B Gene

Variant ID Type Subtype PubMed ID
dgv1247e1 CNV Complex 17122850
dgv1252e1 CNV Complex 17122850
nsv428404 CNV Loss 18775914
dgv1256e1 CNV Complex 17122850
nsv875115 CNV Gain 21882294
dgv1257e1 CNV Complex 17122850
essv1836 CNV CNV 17122850
dgv1260e1 CNV Complex 17122850
esv26126 CNV Gain 19812545
essv5371 CNV CNV 17122850
essv4862 CNV CNV 17122850
nsv482055 CNV Gain 20164927
nsv7328 OTHER Inversion 18451855

Relevant External Links for C2orf27B Gene

HapMap Linkage Disequilibrium report
C2orf27B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C2orf27B Gene

Disorders for C2orf27B Gene

No disorders were found for C2orf27B Gene.

No data available for UniProtKB/Swiss-Prot for C2orf27B Gene

Publications for C2orf27B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  3. Development and application of a DNA microarray-based yeast two-hybrid system. (PMID: 23275563) Suter B. … Wanker E.E. (Nucleic Acids Res. 2013) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4

Products for C2orf27B Gene

Sources for C2orf27B Gene

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