C2orf27B Gene
protein-coding GIFtS: 34
GCID: GC02M132552 (predicted)
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chromosome 2 open reading frame 27B
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Aliases
for C2orf27B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 2 Open Reading Frame 27B1 2 | | MGC502731 | | Uncharacterized Protein LOC4080292 |
Export aliases for C2orf27B gene to outside databasesPrevious GC identifers: GC02M132270 GC02M124546 |
Summaries
for C2orf27B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Genomic Views
for C2orf27B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022135.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for C2orf27B
Other transcription factors
Search SABiosciences Chromatin IP Primers for C2orf27B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C2orf27B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q21 Ensembl cytogenetic band: 2q21.2 HGNC cytogenetic band: 2q21.2C2orf27B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M132552: view genomic region
(about GC identifiers)
Start:
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132,552,534 bp from pter |
End:
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132,559,234 bp from pter |
Size:
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6,701 bases |
Orientation:
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minus strand |
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Proteins
for C2orf27B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CB027_HUMAN, Q580R0 (See
protein sequence)Recommended Name: Uncharacterized protein C2orf27 Size: 203 amino acids; 21517 Da
Secondary accessions: O43575 Q2M1X0 Q52M10 Q86XG2Alternative splicing: 2 isoforms: Q580R0-1 Q580R0-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for C2orf27B: NX_Q580R0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q580R0
C2orf27B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_999626.1
ENSEMBL proteins: ENSP00000304065
Human Recombinant Protein Products:
C2orf27B Antibody Products:
Assay Products for C2orf27B: |
Protein
Domains /
Families
for C2orf27B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q580R0 |
Function
for C2orf27B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf27B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf27B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C2orf27B (NM_214461) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C2orf27B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf27B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf27B |
|
Pathways & Interactions
for C2orf27B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C2orf27B
|
Drugs & Compounds
for C2orf27B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C2orf27B
Search CenterWatch for drugs/clinical trials and news about C2orf27B / CB027
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Transcripts
for C2orf27B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C2orf27B gene: NM_214461.1 Unigene Cluster for C2orf27B: Chromosome 2 open reading frame 27B Hs.145567 [show with all ESTs]Unigene Representative Sequence: BC0435841 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000303798(uc002ttg.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf27B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf27B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C2orf27B (NM_214461) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C2orf27B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf27B |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C2orf27B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C2orf27B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C2orf27B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C2orf27B |
Additional cDNA sequence: BC043584.1 1 DOTS entry: DT.70104636 20 AceView cDNA sequences: BF594073 AI242436 NM_214461 BC043584 H06884 AI418663 BI834689 BV205904 BV205908 BV205911 AW055087 BV205912 AW051903 BV205910 BV205906 BV205903 AA034490 AW294170 BV205914 BV205913
GeneLoc Exon Structure
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Expression
for C2orf27B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C2orf27B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGGTTTGCC
About this image
See C2orf27B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C2orf27B
SOURCE GeneReport for Unigene cluster: Hs.145567
SABiosciences Custom PCR Arrays for C2orf27B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C2orf27B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C2orf27B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C2orf27B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C2orf27B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf27B |
Orthologs
for C2orf27B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for C2orf27B (if available)
TreeFam Gene Tree for C2orf27B (if available) |
Paralogs
for C2orf27B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C2orf27B gene
- C2orf27A1 2
C2orf27B for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for C2orf27B
PGOHUM00000236969 PGOHUM00000245284 PGOHUM00000246274 PGOHUM00000246072
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Genomic Variants
for C2orf27B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for C2orf27B (132552534 - 132559234 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for C2orf27B
3 CNVs: 90006 3393 74268
1 Inversion: 37212 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C2orf27B |
|
Disorders
/ Diseases
for C2orf27B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C2orf27B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C2orf27B gene integrated from 9 sources:
(articles sorted by number of sources associating them with C2orf27B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for C2orf27B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C2orf27B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C2orf27B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C2orf27B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C2orf27B | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C2orf27B gene:
Search GeneIP for patents involving C2orf27B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C2orf27B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C2orf27B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C2orf27B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C2orf27B | | | OriGene Protein Over-expression Lysate for C2orf27B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C2orf27B | | OriGene 3'-UTR Clone for C2orf27B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf27B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf27B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C2orf27B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C2orf27B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C2orf27B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C2orf27B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C2orf27B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C2orf27B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C2orf27B |
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 | | | C2orf27B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf27B |
|  |  |  | | | | Search ThermoFisher Antibodies for C2orf27B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf27B |
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