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Aliases for C2orf27A Gene

Aliases for C2orf27A Gene

  • Chromosome 2 Open Reading Frame 27A 2 3 5
  • Chromosome 2 Open Reading Frame 27 2
  • Uncharacterized Protein C2orf27 3
  • C2orf27A C2orf27B 4
  • C2orf27B 3
  • C2orf27 3

External Ids for C2orf27A Gene

Previous HGNC Symbols for C2orf27A Gene

  • C2orf27

Previous GeneCards Identifiers for C2orf27A Gene

  • GC02P132197
  • GC02P132479
  • GC02P124473

Summaries for C2orf27A Gene

GeneCards Summary for C2orf27A Gene

C2orf27A (Chromosome 2 Open Reading Frame 27A) is a Protein Coding gene. An important paralog of this gene is C2orf27B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf27A Gene

Genomics for C2orf27A Gene

Regulatory Elements for C2orf27A Gene

Enhancers for C2orf27A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F131681 1 Ensembl ENCODE 38.2 -37.6 -37637 6.3 HDGF MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF416 FOS C2orf27A ENSG00000213222 LOC100507460
GH02F131667 0.8 FANTOM5 Ensembl ENCODE 24.4 -53.1 -53090 2.6 HDAC1 CBX3 PKNOX1 ATF1 ARNT TBL1XR1 NFRKB ZBTB40 ZEB1 YY1 C2orf27A PIR46456 PIR51363
GH02F131719 0.2 ENCODE 13.9 -0.9 -933 3.3 JUND HLF PPARG C2orf27A ENSG00000213222 MZT2A LOC100507460
GH02F132264 1.2 FANTOM5 Ensembl ENCODE 13.4 +547.2 547179 9.7 HDGF PKNOX1 ZFP64 SIN3A YBX1 CBX5 ZNF143 ZNF207 FOS KLF13 LOC150776 FAM201B C2orf27A ENSG00000213222 LOC105373622 GC02P132278
GH02F131672 0.8 Ensembl ENCODE 12.3 -49.1 -49145 2.3 PKNOX1 ZFP64 ARID4B SIN3A ZNF48 ZNF2 GLIS2 ZNF143 FOS KLF13 C2orf27A PIR46456 LOC100507460
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C2orf27A on UCSC Golden Path with GeneCards custom track

Promoters for C2orf27A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001827235 1826 399

Genomic Location for C2orf27A Gene

Chromosome:
2
Start:
131,722,375 bp from pter
End:
131,767,404 bp from pter
Size:
45,030 bases
Orientation:
Plus strand

Genomic View for C2orf27A Gene

Genes around C2orf27A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C2orf27A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C2orf27A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf27A Gene

Proteins for C2orf27A Gene

  • Protein details for C2orf27A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q580R0-CB027_HUMAN
    Recommended name:
    Uncharacterized protein C2orf27
    Protein Accession:
    Q580R0
    Secondary Accessions:
    • O43575
    • Q2M1X0
    • Q52M10
    • Q86XG2

    Protein attributes for C2orf27A Gene

    Size:
    203 amino acids
    Molecular mass:
    21517 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C2orf27A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C2orf27A Gene

Post-translational modifications for C2orf27A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C2orf27A Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C2orf27A Gene

Domains & Families for C2orf27A Gene

Protein Domains for C2orf27A Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C2orf27A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C2orf27A: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C2orf27A Gene

Function for C2orf27A Gene

genes like me logo Genes that share phenotypes with C2orf27A: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C2orf27A Gene

Localization for C2orf27A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C2orf27A Gene COMPARTMENTS Subcellular localization image for C2orf27A gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C2orf27A Gene

Pathways & Interactions for C2orf27A Gene

SuperPathways for C2orf27A Gene

No Data Available

Interacting Proteins for C2orf27A Gene

Selected Interacting proteins: Q580R0-CB027_HUMAN for C2orf27A Gene via IID

Gene Ontology (GO) - Biological Process for C2orf27A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C2orf27A Gene

Transcripts for C2orf27A Gene

mRNA/cDNA for C2orf27A Gene

Unigene Clusters for C2orf27A Gene

Chromosome 2 open reading frame 27A:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf27A Gene

No ASD Table

Relevant External Links for C2orf27A Gene

GeneLoc Exon Structure for
C2orf27A
ECgene alternative splicing isoforms for
C2orf27A

Expression for C2orf27A Gene

mRNA expression in normal human tissues for C2orf27A Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C2orf27A Gene



NURSA nuclear receptor signaling pathways regulating expression of C2orf27A Gene:

C2orf27A

SOURCE GeneReport for Unigene cluster for C2orf27A Gene:

Hs.655680
genes like me logo Genes that share expression patterns with C2orf27A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C2orf27A Gene

Orthologs for C2orf27A Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C2orf27A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100615918 34
  • 97.11 (n)
-- 35
  • 92 (a)
OneToMany
Species where no ortholog for C2orf27A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C2orf27A Gene

ENSEMBL:
Gene Tree for C2orf27A (if available)
TreeFam:
Gene Tree for C2orf27A (if available)

Paralogs for C2orf27A Gene

Paralogs for C2orf27A Gene

genes like me logo Genes that share paralogs with C2orf27A: view

Variants for C2orf27A Gene

Sequence variations from dbSNP and Humsavar for C2orf27A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10168830 -- 131,734,191(+) AACCG(C/T)GAATC intron-variant
rs10182422 -- 131,727,659(+) TTTTT(C/T)CTTTT intron-variant
rs10184806 -- 131,724,857(+) TTAAA(A/G)TTTAT intron-variant
rs10184807 -- 131,759,721(+) CCTGG(A/G)CGTCC intron-variant
rs10187584 -- 131,725,070(+) CTAAC(C/T)TGGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C2orf27A Gene

Variant ID Type Subtype PubMed ID
dgv2247e59 CNV duplication 20981092
esv24587 CNV gain+loss 19812545
esv26126 CNV gain 19812545
esv2759092 CNV gain+loss 17122850
esv2762850 CNV gain 21179565
esv3592492 CNV gain 21293372
esv3592493 CNV loss 21293372
esv3592494 CNV gain 21293372
nsv1011966 CNV loss 25217958
nsv10186 CNV loss 18304495
nsv1072033 CNV deletion 25765185
nsv1132513 CNV duplication 24896259
nsv1139737 CNV duplication 24896259
nsv1151957 CNV duplication 26484159
nsv428404 CNV loss 18775914
nsv471420 CNV gain 19718026
nsv482054 CNV gain 20164927
nsv514979 CNV gain 21397061
nsv527590 CNV loss 19592680
nsv583146 CNV gain 21841781
nsv820012 CNV loss 19587683
nsv834377 CNV gain 17160897
nsv953174 CNV duplication 24416366
nsv953175 CNV duplication 24416366
nsv953176 CNV deletion 24416366
nsv961656 CNV duplication 23825009
nsv961888 CNV duplication 23825009
nsv961889 CNV duplication 23825009
nsv963725 CNV duplication 23825009
nsv997248 CNV loss 25217958
nsv999735 CNV gain 25217958

Relevant External Links for C2orf27A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C2orf27A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for C2orf27A Gene

Disorders for C2orf27A Gene

Relevant External Links for C2orf27A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C2orf27A

No disorders were found for C2orf27A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C2orf27A Gene

Publications for C2orf27A Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3 64
  4. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C2orf27A Gene

Sources for C2orf27A Gene

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