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Aliases for C2orf27A Gene

Aliases for C2orf27A Gene

  • Chromosome 2 Open Reading Frame 27A 2 3 5
  • Chromosome 2 Open Reading Frame 27 2
  • C2orf27A C2orf27B 4
  • C2orf27B 3
  • C2orf27 3

External Ids for C2orf27A Gene

Previous HGNC Symbols for C2orf27A Gene

  • C2orf27

Previous GeneCards Identifiers for C2orf27A Gene

  • GC02P132197
  • GC02P132479
  • GC02P124473

Summaries for C2orf27A Gene

GeneCards Summary for C2orf27A Gene

C2orf27A (Chromosome 2 Open Reading Frame 27A) is a Protein Coding gene. An important paralog of this gene is C2orf27B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf27A Gene

Genomics for C2orf27A Gene

Regulatory Elements for C2orf27A Gene

Enhancers for C2orf27A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C2orf27A on UCSC Golden Path with GeneCards custom track

Promoters for C2orf27A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C2orf27A on UCSC Golden Path with GeneCards custom track

Genomic Location for C2orf27A Gene

Chromosome:
2
Start:
131,722,375 bp from pter
End:
131,767,404 bp from pter
Size:
45,030 bases
Orientation:
Plus strand

Genomic View for C2orf27A Gene

Genes around C2orf27A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C2orf27A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C2orf27A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf27A Gene

Proteins for C2orf27A Gene

  • Protein details for C2orf27A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q580R0-CB027_HUMAN
    Recommended name:
    Uncharacterized protein C2orf27
    Protein Accession:
    Q580R0
    Secondary Accessions:
    • O43575
    • Q2M1X0
    • Q52M10
    • Q86XG2

    Protein attributes for C2orf27A Gene

    Size:
    203 amino acids
    Molecular mass:
    21517 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C2orf27A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C2orf27A Gene

Proteomics data for C2orf27A Gene at MOPED

Post-translational modifications for C2orf27A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C2orf27A Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C2orf27A Gene

Domains & Families for C2orf27A Gene

Protein Domains for C2orf27A Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C2orf27A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C2orf27A: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C2orf27A Gene

Function for C2orf27A Gene

Phenotypes for C2orf27A Gene

genes like me logo Genes that share phenotypes with C2orf27A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C2orf27A Gene

Localization for C2orf27A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C2orf27A Gene COMPARTMENTS Subcellular localization image for C2orf27A gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C2orf27A Gene

Pathways & Interactions for C2orf27A Gene

SuperPathways for C2orf27A Gene

No Data Available

Interacting Proteins for C2orf27A Gene

Gene Ontology (GO) - Biological Process for C2orf27A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C2orf27A Gene

Drugs & Compounds for C2orf27A Gene

No Compound Related Data Available

Transcripts for C2orf27A Gene

Unigene Clusters for C2orf27A Gene

Chromosome 2 open reading frame 27A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf27A Gene

No ASD Table

Relevant External Links for C2orf27A Gene

GeneLoc Exon Structure for
C2orf27A
ECgene alternative splicing isoforms for
C2orf27A

Expression for C2orf27A Gene

mRNA expression in normal human tissues for C2orf27A Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C2orf27A Gene



SOURCE GeneReport for Unigene cluster for C2orf27A Gene Hs.655680

genes like me logo Genes that share expression patterns with C2orf27A: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C2orf27A Gene

Orthologs for C2orf27A Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C2orf27A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100615918 35
  • 97.11 (n)
  • 93.88 (a)
-- 36
  • 92 (a)
OneToMany
Species with no ortholog for C2orf27A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C2orf27A Gene

ENSEMBL:
Gene Tree for C2orf27A (if available)
TreeFam:
Gene Tree for C2orf27A (if available)

Paralogs for C2orf27A Gene

Paralogs for C2orf27A Gene

genes like me logo Genes that share paralogs with C2orf27A: view

Variants for C2orf27A Gene

Sequence variations from dbSNP and Humsavar for C2orf27A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
VAR_033657 -
rs1808774 -- 131,722,478(+) TATAA(C/T)ATGCA upstream-variant-2KB
rs1808777 -- 131,762,808(-) GACAC(C/T)AAGCC intron-variant
rs1821698 -- 131,722,890(+) ATCTC(A/T)GTACC intron-variant
rs1821699 -- 131,722,956(+) TCATT(A/C)AGCTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C2orf27A Gene

Variant ID Type Subtype PubMed ID
dgv1247e1 CNV Complex 17122850
dgv1252e1 CNV Complex 17122850
nsv428404 CNV Loss 18775914
dgv1256e1 CNV Complex 17122850
nsv875115 CNV Gain 21882294
dgv1257e1 CNV Complex 17122850
essv1836 CNV CNV 17122850
dgv1260e1 CNV Complex 17122850
nsv10186 CNV Loss 18304495
nsv820012 CNV Loss 19587683
nsv834377 CNV Gain 17160897
esv24587 CNV Gain+Loss 19812545
nsv875122 CNV Loss 21882294
nsv527590 CNV Loss 19592680
nsv471420 CNV Duplication 19718026
nsv482054 CNV Gain 20164927
nsv514979 CNV Complex 21397061
esv26126 CNV Gain 19812545

Relevant External Links for C2orf27A Gene

HapMap Linkage Disequilibrium report
C2orf27A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for C2orf27A Gene

Disorders for C2orf27A Gene

Relevant External Links for C2orf27A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C2orf27A

No disorders were found for C2orf27A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C2orf27A Gene

Publications for C2orf27A Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 67
  2. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3
  3. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C2orf27A Gene

Sources for C2orf27A Gene

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