C2orf16 Gene
protein-coding GIFtS: 38
GCID: GC02P027799
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chromosome 2 open reading frame 16
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Aliases
for C2orf16 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 2 Open Reading Frame 161 2 | | DKFZp434G1181 | | Uncharacterized Protein C2orf162 |
Export aliases for C2orf16 gene to outside databasesPrevious GC identifers: GC02P027777 GC02P027714 GC02P027652 GC02P027541 |
Summaries
for C2orf16 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C2orf16 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C2orf16 gene promoter:
STAT5B USF1 Sox5 AML1a FOXD1 XBP-1 LCR-F1 Cdc5 PPAR-gamma1 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C2orf16
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C2orf16 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p23.3 Ensembl cytogenetic band: 2p23.3 HGNC cytogenetic band: 2p23.3C2orf16 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P027799: view genomic region
(about GC identifiers)
Start:
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27,799,389 bp from pter |
End:
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27,805,589 bp from pter |
Size:
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6,201 bases |
Orientation:
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plus strand |
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Proteins
for C2orf16 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CB016_HUMAN, Q68DN1 (See
protein sequence)Recommended Name: Uncharacterized protein C2orf16 Size: 1984 amino acids; 224321 Da
Sequence caution: Sequence=AAX93198.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B9EIQ4 Q53S01 Q8ND64 Q9H088Explore the universe of human proteins at neXtProt for C2orf16: NX_Q68DN1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q68DN1
C2orf16 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115642.3
ENSEMBL proteins: ENSP00000386190
Human Recombinant Protein Products:
C2orf16 Antibody Products:
Assay Products for C2orf16: |
Protein
Domains /
Families
for C2orf16 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q68DN1 UniProtKB/Swiss-Prot: CB016_HUMAN, Q68DN1Domain: The P-S-E-R-S-H-H-S repeats give rise to an antiparallel beta-structure |
Function
for C2orf16 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf16
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C2orf16 (NM_032266) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C2orf16 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf16 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf16 |
1 GenomeRNAi human phenotype for C2orf16:
|
Pathways & Interactions
for C2orf16 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C2orf16
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for C2orf16 (Q68DN13 ENSP000003861904) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C2orf16 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C2orf16
Search CenterWatch for drugs/clinical trials and news about C2orf16 / CB016
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Transcripts
for C2orf16 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C2orf16 gene: NM_032266.3 Unigene Cluster for C2orf16: Chromosome 2 open reading frame 16 Hs.131021 [show with all ESTs]Unigene Representative Sequence: CR7493351 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000408964(uc002rkz.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf16
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C2orf16 (NM_032266) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C2orf16 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf16 |
Additional cDNA sequence: AL136898.1 AL834384.1 BC115376.1 BC115377.1 BC140828.1 CR749335.1 1 DOTS entry: DT.40128569 24/195 AceView cDNA sequences (see all 195): AI768018 BM717631 AI765343 BQ478203 BE669524 NM_032434 N39719 CK826128 BM782796 BQ215308 BM669485 BI861228 BE220056 AK057028 AA306083 AL833748 AW016695 BE675109 NM_032266 BG057669 BX115888 BE047133 AL136898 CD722360
GeneLoc Exon Structure
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Expression
for C2orf16 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C2orf16 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAACTGCTTT
About this image
See C2orf16 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C2orf16
SOURCE GeneReport for Unigene cluster: Hs.131021
SABiosciences Custom PCR Arrays for C2orf16
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C2orf16
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C2orf16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C2orf16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C2orf16 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf16 |
Orthologs
for C2orf16 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C2orf16 gene from 1/6 species (see all 6) About this table
ENSEMBL Gene Tree for C2orf16 (if available)
TreeFam Gene Tree for C2orf16 (if available) |
Paralogs
for C2orf16 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C2orf16 gene
- SRRM32 SRRM22 SRRM42 SRRM12 SRRM52
C2orf16 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for C2orf16
PGOHUM00000240606 PGOHUM00000240607
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Genomic Variants
for C2orf16 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for C2orf16 (27799389 - 27805589 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C2orf16
1 CNV: 9400 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C2orf16 |
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Disorders
/ Diseases
for C2orf16 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C2orf16 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C2orf16 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C2orf16) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Genome-wide association study identifies loci influenc ing concentrations of liver enzymes in plasma. (PubMed id 22001757)1 Chambers J.C....Kooner J.S. (2011)
- A bivariate genome-wide approach to metabolic syndrom e: STAMPEED consortium. (PubMed id 21386085)1 Kraja A.T....Borecki I.B. (2011)
- Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. (PubMed id 20705733)1 O'Seaghdha C.M....KAPttgen A. (2010)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for C2orf16 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C2orf16 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C2orf16 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C2orf16 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C2orf16 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C2orf16 gene:
Search GeneIP for patents involving C2orf16
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C2orf16 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C2orf16 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C2orf16 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C2orf16 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C2orf16 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf16 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf16 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C2orf16 | | OriGene Custom Protein Services for C2orf16 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C2orf16 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C2orf16 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C2orf16 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C2orf16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C2orf16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C2orf16 |
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| | | | Search Tocris compounds for C2orf16 |
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 | | | C2orf16 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf16 |
|  |  |  | | | | Search ThermoFisher Antibodies for C2orf16 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf16 |
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