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Aliases for C2orf16 Gene

Aliases for C2orf16 Gene

  • Chromosome 2 Open Reading Frame 16 2 3
  • P-S-E-R-S-H-H-S Repeats Containing 2

External Ids for C2orf16 Gene

Previous GeneCards Identifiers for C2orf16 Gene

  • GC02P027777
  • GC02P027714
  • GC02P027652
  • GC02P027799
  • GC02P027541

Summaries for C2orf16 Gene

GeneCards Summary for C2orf16 Gene

C2orf16 (Chromosome 2 Open Reading Frame 16) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C2orf16 Gene

Genomics for C2orf16 Gene

Regulatory Elements for C2orf16 Gene

Genomic Location for C2orf16 Gene

27,576,522 bp from pter
27,582,722 bp from pter
6,201 bases
Plus strand

Genomic View for C2orf16 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C2orf16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C2orf16 Gene

Proteins for C2orf16 Gene

  • Protein details for C2orf16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C2orf16
    Protein Accession:
    Secondary Accessions:
    • B9EIQ4
    • Q53S01
    • Q8ND64
    • Q9H088

    Protein attributes for C2orf16 Gene

    1984 amino acids
    Molecular mass:
    224321 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAX93198.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for C2orf16 Gene

Proteomics data for C2orf16 Gene at MOPED

Post-translational modifications for C2orf16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C2orf16 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C2orf16 Gene

Domains for C2orf16 Gene

Protein Domains for C2orf16 Gene


Suggested Antigen Peptide Sequences for C2orf16 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q68DN1
  • The P-S-E-R-S-H-H-S repeats give rise to an antiparallel beta-structure
genes like me logo Genes that share domains with C2orf16: view

No data available for Gene Families for C2orf16 Gene

Function for C2orf16 Gene

Phenotypes for C2orf16 Gene

GenomeRNAi human phenotypes for C2orf16:
genes like me logo Genes that share phenotypes with C2orf16: view

Animal Model Products

CRISPR Products

miRNA for C2orf16 Gene

miRTarBase miRNAs that target C2orf16

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C2orf16

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for C2orf16 Gene

Localization for C2orf16 Gene

Subcellular locations from

Jensen Localization Image for C2orf16 Gene COMPARTMENTS Subcellular localization image for C2orf16 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for C2orf16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 21630459
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with C2orf16: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C2orf16 Gene

Pathways for C2orf16 Gene

SuperPathways for C2orf16 Gene

No Data Available

Interacting Proteins for C2orf16 Gene

Selected Interacting proteins: Q68DN1-CB016_HUMAN for C2orf16 Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for C2orf16 Gene


No data available for Pathways by source for C2orf16 Gene

Transcripts for C2orf16 Gene

mRNA/cDNA for C2orf16 Gene

(195) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C2orf16 Gene

Chromosome 2 open reading frame 16:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C2orf16

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C2orf16 Gene

No ASD Table

Relevant External Links for C2orf16 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C2orf16 Gene

mRNA expression in normal human tissues for C2orf16 Gene

mRNA differential expression in normal tissues according to GTEx for C2orf16 Gene

This gene is overexpressed in Testis (33.6).

SOURCE GeneReport for Unigene cluster for C2orf16 Gene Hs.131021

genes like me logo Genes that share expressions with C2orf16: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for C2orf16 Gene

Orthologs for C2orf16 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C2orf16 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C11H2orf16 35
  • 78.38 (n)
  • 63.24 (a)
C2orf16 36
  • 62 (a)
(Canis familiaris)
Mammalia LOC102156387 35
  • 80.19 (n)
  • 65.6 (a)
cfa-mir-1837-2 36
  • 60 (a)
cfa-mir-1837-2 36
  • 62 (a)
(Mus musculus)
Mammalia LOC102635990 35
  • 68.68 (n)
  • 49.39 (a)
Gm17695 16
4932415D10Rik 36
  • 56 (a)
(Pan troglodytes)
Mammalia C2AH2orf16 35
  • 98.96 (n)
  • 97.5 (a)
C2orf16 36
  • 96 (a)
(Rattus norvegicus)
Mammalia LOC100359615 35
  • 68.32 (n)
  • 50.6 (a)
Species with no ortholog for C2orf16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C2orf16 Gene

Gene Tree for C2orf16 (if available)
Gene Tree for C2orf16 (if available)

Paralogs for C2orf16 Gene Pseudogenes for C2orf16 Gene

genes like me logo Genes that share paralogs with C2orf16: view

No data available for Paralogs for C2orf16 Gene

Variants for C2orf16 Gene

Sequence variations from dbSNP and Humsavar for C2orf16 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1919125 - 27,578,536(+) ATGTA(C/G)TCAAG reference, missense
rs1919126 - 27,578,551(+) GTCTG(A/C)AGAAT missense, reference
rs1919127 - 27,578,626(+) GGCTG(C/T)GAAAT missense, reference
rs1919128 - 27,578,892(+) CAGAT(A/G)TTTTG reference, missense
rs3811644 -- 27,579,938(-) CACTG(C/T)AGGCA reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for C2orf16 Gene

Variant ID Type Subtype PubMed ID
nsv817684 CNV Gain 17921354

Relevant External Links for C2orf16 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C2orf16 Gene

Disorders for C2orf16 Gene

Relevant External Links for C2orf16

Genetic Association Database (GAD)

No disorders were found for C2orf16 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C2orf16 Gene

Publications for C2orf16 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  2. A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. (PMID: 21386085) Kraja A.T. … Borecki I.B. (Diabetes 2011) 3 48
  3. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3

Products for C2orf16 Gene

Sources for C2orf16 Gene

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