C2orf15 Gene
protein-coding GIFtS: 34
GCID: GC02P099757 (predicted)
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chromosome 2 open reading frame 15
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Aliases for C2orf15 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Chromosome 2 Open Reading Frame 151 2 | | MGC297621 | | Uncharacterized Protein C2orf152 |
Export aliases for C2orf15 gene to outside databasesPrevious GC identifers: GC02P099379 GC02P099216 GC02P099124 GC02P093523 |
Summaries for C2orf15 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Views for C2orf15 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022171.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the C2orf15 gene promoter: Sp1 Pax-5 MIF-1 Cdc5 YY1 Evi-1 Egr-4 Gfi-1 S8 Pax-4a Other transcription factors
Search SABiosciences Chromatin IP Primers for C2orf15
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C2orf15 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q11.2 Ensembl cytogenetic band: 2q11.2 HGNC cytogenetic band: 2q11.2C2orf15 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P099757: view genomic region
(about GC identifiers)
Start:
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99,757,948 bp from pter |
End:
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99,939,204 bp from pter |
Size:
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181,257 bases |
Orientation:
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plus strand |
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Proteins for C2orf15 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CB015_HUMAN, Q8WU43 (See
protein sequence)Recommended Name: Uncharacterized protein C2orf15 Size: 125 amino acids; 13691 DaExplore the universe of human proteins at neXtProt for C2orf15: NX_Q8WU43
C2orf15 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_653307.1 ENSEMBL proteins: ENSP00000302202 ENSP00000390891 ENSP00000386654 ENSP00000420959 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
C2orf15 for ontologies About GeneDecksing
C2orf15 Antibody Products: Assay Products for C2orf15: |
Protein
Domains / Families for C2orf15 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8WU43 |
Function for C2orf15 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf15 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf15 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C2orf15 (NM_144706) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C2orf15 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf15  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf15 |
1 GenomeRNAi human phenotype for C2orf15:
|
Pathways & Interactions for C2orf15 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C2orf15
|
Drugs & Compounds for C2orf15 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for C2orf15 Search CenterWatch for drugs/clinical trials and news about C2orf15 / CB015 
|
Transcripts for C2orf15 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for C2orf15 gene: NM_144706.2 Unigene Cluster for C2orf15: Chromosome 2 open reading frame 15 Hs.352211 [show with all ESTs]Unigene Representative Sequence: BC0212646 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000302513(uc002szk.3) ENST00000424491(uc002szl.1) ENST00000409684 ENST00000496794 ENST00000465095 ENST00000512183
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf15 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf15 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C2orf15 (NM_144706) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C2orf15 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf15  |
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C2orf15 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C2orf15 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C2orf15 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C2orf15 |
Additional cDNA sequence: AK314133.1 BC021264.2 6 DOTS entries: DT.40125674 DT.40227621 DT.91816024 DT.101974845 DT.120952339 DT.120952502 24/317 AceView cDNA sequences (see all 317): T71680 NM_144706 AI469440 CR608673 BF445559 AA865778 AI791367 AA641895 CR603303 BM771042 BM767333 NM_145198 BQ020788 AI685945 BQ576134 AI916199 CR602357 AI148460 NM_016503 AI247681 AI434227 AA743157 AI732972 AA662484 GeneLoc Exon Structure
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Expression for C2orf15 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C2orf15 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CCATTGTACT
About this image See C2orf15 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for C2orf15
SOURCE GeneReport for Unigene cluster: Hs.352211 SABiosciences Custom PCR Arrays for C2orf15
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C2orf15 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C2orf15 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C2orf15 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C2orf15 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf15 |
Orthologs for C2orf15 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C2orf15 gene from 4/12 species (see all 12) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
MRPL306 |
Uncharacterized protein |
58(a) |
1 → many |
1(136639288-136641672) |
lizard (Anolis carolinensis) |
Reptilia |
MRPL306 |
-- |
65(a) |
1 → many |
GL343940.1(96075-98567) |
zebrafish (Danio rerio) |
Actinopterygii |
zgc:1120896 |
zgc:112089 |
59(a) |
1 → many |
9(22858108-22859258) |
fruit fly (Drosophila melanogaster) |
Insecta |
mRpL306 |
mitochondrial ribosomal protein L30 |
23(a) |
1 → many |
X(4541910-4542679) |
ENSEMBL Gene Tree for C2orf15 (if available) TreeFam Gene Tree for C2orf15 (if available)  |
Paralogs for C2orf15 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for C2orf15 gene
- MRPL302
C2orf15 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for C2orf15 PGOHUM00000243650
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Genomic Variants for C2orf15 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C2orf15 |
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Disorders
/ Diseases for C2orf15 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications for C2orf15 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C2orf15 gene integrated from 9 sources: (articles sorted by number of sources associating them with C2orf15) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Large-scale genome-wide association analysis of bipol ar disorder identifies a new susceptibility locus near ODZ4. (PubMed id 21926972)1 Sklar P....Purcell S.M. (2011)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for C2orf15 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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Genome Databases showing C2orf15 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing C2orf15 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C2orf15 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for C2orf15 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C2orf15 gene: Search GeneIP for patents involving C2orf15
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for C2orf15 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for C2orf15 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C2orf15 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C2orf15 | | OriGene Protein Over-expression Lysate for C2orf15 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for C2orf15 | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf15 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C2orf15 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for C2orf15 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | Search Tocris compounds for C2orf15 |
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 | | C2orf15 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C2orf15 |
|  |  |  | | | Search ThermoFisher Antibodies for C2orf15 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C2orf15 |
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