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Aliases for C22orf42 Gene

Aliases for C22orf42 Gene

  • Chromosome 22 Open Reading Frame 42 2 3
  • DJ90G24.6 3

External Ids for C22orf42 Gene

Previous GeneCards Identifiers for C22orf42 Gene

  • GC22M030875
  • GC22M032544
  • GC22M015501

Summaries for C22orf42 Gene

GeneCards Summary for C22orf42 Gene

C22orf42 (Chromosome 22 Open Reading Frame 42) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C22orf42 Gene

Genomics for C22orf42 Gene

Regulatory Elements for C22orf42 Gene

Genomic Location for C22orf42 Gene

32,149,006 bp from pter
32,160,432 bp from pter
11,427 bases
Minus strand

Genomic View for C22orf42 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for C22orf42 Gene

Proteins for C22orf42 Gene

  • Protein details for C22orf42 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C22orf42
    Protein Accession:
    Secondary Accessions:
    • A4QPH5

    Protein attributes for C22orf42 Gene

    251 amino acids
    Molecular mass:
    27691 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C22orf42 Gene

Proteomics data for C22orf42 Gene at MOPED

Post-translational modifications for C22orf42 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C22orf42 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C22orf42 Gene

Domains & Families for C22orf42 Gene

Protein Domains for C22orf42 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C22orf42: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C22orf42 Gene

Function for C22orf42 Gene

Phenotypes for C22orf42 Gene

GenomeRNAi human phenotypes for C22orf42:
genes like me logo Genes that share phenotypes with C22orf42: view

Animal Model Products

CRISPR Products

miRNA for C22orf42 Gene

miRTarBase miRNAs that target C22orf42

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C22orf42

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C22orf42 Gene

Localization for C22orf42 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C22orf42 Gene

Pathways & Interactions for C22orf42 Gene

SuperPathways for C22orf42 Gene

No Data Available

Interacting Proteins for C22orf42 Gene

Gene Ontology (GO) - Biological Process for C22orf42 Gene


No data available for Pathways by source and SIGNOR curated interactions for C22orf42 Gene

Drugs & Compounds for C22orf42 Gene

No Compound Related Data Available

Transcripts for C22orf42 Gene

mRNA/cDNA for C22orf42 Gene

Unigene Clusters for C22orf42 Gene

Chromosome 22 open reading frame 42:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C22orf42

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C22orf42 Gene

No ASD Table

Relevant External Links for C22orf42 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C22orf42 Gene

mRNA expression in normal human tissues for C22orf42 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C22orf42 Gene

This gene is overexpressed in Testis (x24.8) and Brain - Hypothalamus (x18.0).

SOURCE GeneReport for Unigene cluster for C22orf42 Gene Hs.426551

genes like me logo Genes that share expression patterns with C22orf42: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C22orf42 Gene

Orthologs for C22orf42 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C22orf42 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C22H22orf42 35
  • 98.07 (n)
  • 95.65 (a)
C22orf42 36
  • 95 (a)
Species with no ortholog for C22orf42:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C22orf42 Gene

Gene Tree for C22orf42 (if available)
Gene Tree for C22orf42 (if available)

Paralogs for C22orf42 Gene Pseudogenes for C22orf42 Gene

genes like me logo Genes that share paralogs with C22orf42: view

No data available for Paralogs for C22orf42 Gene

Variants for C22orf42 Gene

Sequence variations from dbSNP and Humsavar for C22orf42 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs136403 -- 32,157,971(+) CGGGG(A/G)TTGTT intron-variant
rs1297793 -- 32,156,423(-) TTCAC(C/T)CAGAA intron-variant
rs1297794 -- 32,153,462(-) catct(A/C)ctgta intron-variant
rs2019949 -- 32,150,959(+) CTACA(A/C/T)GTAAA intron-variant, missense, reference
rs2019952 -- 32,151,099(+) TTCAC(C/T)TGGTG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for C22orf42 Gene

Variant ID Type Subtype PubMed ID
nsv834177 CNV Gain 17160897
esv2422247 CNV Duplication 17116639
nsv834178 CNV Loss 17160897

Variation tolerance for C22orf42 Gene

Residual Variation Intolerance Score: 88.81% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.39; 42.34% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C22orf42 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C22orf42 Gene

Disorders for C22orf42 Gene

Relevant External Links for C22orf42

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C22orf42: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C22orf42 Gene

Publications for C22orf42 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 67
  3. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 67

Products for C22orf42 Gene

Sources for C22orf42 Gene

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