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Aliases for C22orf39 Gene

Aliases for C22orf39 Gene

  • Chromosome 22 Open Reading Frame 39 2 3

External Ids for C22orf39 Gene

Previous GeneCards Identifiers for C22orf39 Gene

  • GC22M017808
  • GC22M003049

Summaries for C22orf39 Gene

GeneCards Summary for C22orf39 Gene

C22orf39 (Chromosome 22 Open Reading Frame 39) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C22orf39 Gene

Genomics for C22orf39 Gene

Regulatory Elements for C22orf39 Gene

Genomic Location for C22orf39 Gene

Start:
19,351,368 bp from pter
End:
19,448,232 bp from pter
Size:
96,865 bases
Orientation:
Minus strand

Genomic View for C22orf39 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C22orf39 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C22orf39 Gene

Proteins for C22orf39 Gene

  • Protein details for C22orf39 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P5X5-CV039_HUMAN
    Recommended name:
    UPF0545 protein C22orf39
    Protein Accession:
    Q6P5X5
    Secondary Accessions:
    • A8MTW6
    • D3DX18
    • F5H3A8
    • J3KNP9

    Protein attributes for C22orf39 Gene

    Size:
    142 amino acids
    Molecular mass:
    16805 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH62599.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAF82762.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAG30225.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=EAX03040.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for C22orf39 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C22orf39 Gene

Proteomics data for C22orf39 Gene at MOPED

Post-translational modifications for C22orf39 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C22orf39 Gene

No data available for DME Specific Peptides for C22orf39 Gene

Domains for C22orf39 Gene

Protein Domains for C22orf39 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C22orf39 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P5X5

UniProtKB/Swiss-Prot:

CV039_HUMAN :
  • Q6P5X5
Family:
  • Belongs to the UPF0545 family.
genes like me logo Genes that share domains with C22orf39: view

No data available for Gene Families for C22orf39 Gene

Function for C22orf39 Gene

Gene Ontology (GO) - Molecular Function for C22orf39 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C22orf39: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C22orf39 Gene

Localization for C22orf39 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C22orf39 Gene COMPARTMENTS Subcellular localization image for C22orf39 gene
Compartment Confidence
extracellular 3
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C22orf39 Gene

Pathways for C22orf39 Gene

SuperPathways for C22orf39 Gene

No Data Available

Interacting Proteins for C22orf39 Gene

Gene Ontology (GO) - Biological Process for C22orf39 Gene

None

No data available for Pathways by source for C22orf39 Gene

Transcripts for C22orf39 Gene

Unigene Clusters for C22orf39 Gene

Chromosome 22 open reading frame 39:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C22orf39 Gene

No ASD Table

Relevant External Links for C22orf39 Gene

GeneLoc Exon Structure for
C22orf39
ECgene alternative splicing isoforms for
C22orf39

Expression for C22orf39 Gene

mRNA expression in normal human tissues for C22orf39 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C22orf39 Gene

This gene is overexpressed in Muscle - Skeletal (4.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C22orf39 Gene

SOURCE GeneReport for Unigene cluster for C22orf39 Gene Hs.659565

genes like me logo Genes that share expressions with C22orf39: view

No data available for mRNA Expression by UniProt/SwissProt for C22orf39 Gene

Orthologs for C22orf39 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C22orf39 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C22H22orf39 35
  • 98.3 (n)
  • 96.94 (a)
C22orf39 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C22orf39 36
  • 56 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C22orf39 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2510002D24Rik 16
2510002D24Rik 36
  • 72 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C22orf39 36
  • 56 (a)
OneToOne
chicken
(Gallus gallus)
Aves C22orf39 36
  • 49 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C22orf39 36
  • 47 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii C8H22orf39 36
  • 44 (a)
OneToOne
Species with no ortholog for C22orf39:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C22orf39 Gene

ENSEMBL:
Gene Tree for C22orf39 (if available)
TreeFam:
Gene Tree for C22orf39 (if available)

Paralogs for C22orf39 Gene

Selected SIMAP similar genes for C22orf39 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with C22orf39: view

No data available for Paralogs for C22orf39 Gene

Variants for C22orf39 Gene

Sequence variations from dbSNP and Humsavar for C22orf39 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs11744 -- 19,440,988(-) TAACA(C/T)TGGGG utr-variant-3-prime
rs712979 -- 19,443,515(-) AAAGC(C/T)ATTTC intron-variant, utr-variant-3-prime
rs756648 -- 19,443,962(-) GATGG(C/T)GGTCC intron-variant, utr-variant-3-prime
rs756649 -- 19,443,873(-) TAAAC(A/G)GTTGT intron-variant, utr-variant-3-prime
rs885975 -- 19,442,949(+) AAATG(C/T)TCATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C22orf39 Gene

Variant ID Type Subtype PubMed ID
nsv435744 CNV Deletion 17901297
nsv914263 CNV Gain 21882294
nsv834124 CNV Loss 17160897
nsv834127 CNV Loss 17160897
dgv4839n71 CNV Loss 21882294
dgv4840n71 CNV Loss 21882294
esv2751940 CNV Gain 17911159

Relevant External Links for C22orf39 Gene

HapMap Linkage Disequilibrium report
C22orf39

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C22orf39 Gene

Disorders for C22orf39 Gene

No disorders were found for C22orf39 Gene.

No data available for UniProtKB/Swiss-Prot for C22orf39 Gene

Publications for C22orf39 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 3 4
  3. Effects of chronic ascariasis and trichuriasis on cytokine production and gene expression in human blood: a cross-sectional study. (PMID: 21666788) Reina Ortiz M. … Cooper P.J. (PLoS Negl Trop Dis 2011) 3
  4. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for C22orf39 Gene

Sources for C22orf39 Gene

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