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Aliases for C22orf15 Gene

Aliases for C22orf15 Gene

  • Chromosome 22 Open Reading Frame 15 2 3
  • Protein N27C7-3 3 4
  • N27C7-3 3

External Ids for C22orf15 Gene

Previous GeneCards Identifiers for C22orf15 Gene

  • GC22P022430
  • GC22P022431
  • GC22P022435
  • GC22P024105
  • GC22P007093

Summaries for C22orf15 Gene

GeneCards Summary for C22orf15 Gene

C22orf15 (Chromosome 22 Open Reading Frame 15) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C22orf15 Gene

Genomics for C22orf15 Gene

Regulatory Elements for C22orf15 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C22orf15 Gene

23,760,033 bp from pter
23,765,863 bp from pter
5,831 bases
Plus strand

Genomic View for C22orf15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C22orf15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C22orf15 Gene

Proteins for C22orf15 Gene

  • Protein details for C22orf15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C22orf15
    Protein Accession:
    Secondary Accessions:
    • Q6ICJ7

    Protein attributes for C22orf15 Gene

    148 amino acids
    Molecular mass:
    16487 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C22orf15 Gene


neXtProt entry for C22orf15 Gene

Proteomics data for C22orf15 Gene at MOPED

Post-translational modifications for C22orf15 Gene

No Post-translational modifications

Other Protein References for C22orf15 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C22orf15 Gene

Domains & Families for C22orf15 Gene

Protein Domains for C22orf15 Gene


Suggested Antigen Peptide Sequences for C22orf15 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C22orf15: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C22orf15 Gene

Function for C22orf15 Gene

genes like me logo Genes that share phenotypes with C22orf15: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C22orf15

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C22orf15 Gene

Localization for C22orf15 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C22orf15 Gene

Pathways & Interactions for C22orf15 Gene

SuperPathways for C22orf15 Gene

No Data Available

Interacting Proteins for C22orf15 Gene

Gene Ontology (GO) - Biological Process for C22orf15 Gene


No data available for Pathways by source and SIGNOR curated interactions for C22orf15 Gene

Drugs & Compounds for C22orf15 Gene

No Compound Related Data Available

Transcripts for C22orf15 Gene

Unigene Clusters for C22orf15 Gene

Chromosome 22 open reading frame 15:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C22orf15

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C22orf15 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5 ^ 6 ^ 7a · 7b
SP1: - - -
SP2: - - - -

Relevant External Links for C22orf15 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C22orf15 Gene

mRNA expression in normal human tissues for C22orf15 Gene

mRNA differential expression in normal tissues according to GTEx for C22orf15 Gene

This gene is overexpressed in Testis (x8.1), Fallopian Tube (x5.1), Lung (x4.6), and Pituitary (x4.1).

Protein differential expression in normal tissues from HIPED for C22orf15 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C22orf15 Gene

SOURCE GeneReport for Unigene cluster for C22orf15 Gene Hs.116254

genes like me logo Genes that share expression patterns with C22orf15: view

Protein tissue co-expression partners for C22orf15 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C22orf15 Gene

Orthologs for C22orf15 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C22orf15 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C17H22orf15 35
  • 76.26 (n)
  • 63.01 (a)
C22orf15 36
  • 52 (a)
(Canis familiaris)
Mammalia C26H22orf15 35
  • 77.08 (n)
  • 68.06 (a)
C22orf15 36
  • 66 (a)
(Mus musculus)
Mammalia Gm867 35
  • 69.27 (n)
  • 59.57 (a)
Gm867 16
Gm867 36
  • 52 (a)
(Pan troglodytes)
Mammalia C22H22orf15 35
  • 99.1 (n)
  • 99.32 (a)
C22orf15 36
  • 59 (a)
(Rattus norvegicus)
Mammalia RGD1564162 35
  • 68.81 (n)
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia C22orf15 36
  • 49 (a)
Species with no ortholog for C22orf15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C22orf15 Gene

Gene Tree for C22orf15 (if available)
Gene Tree for C22orf15 (if available)

Paralogs for C22orf15 Gene

No data available for Paralogs for C22orf15 Gene

Variants for C22orf15 Gene

Sequence variations from dbSNP and Humsavar for C22orf15 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs2330621 -- 23,763,087(+) GGAGT(C/T)TTGGA utr-variant-5-prime, intron-variant, upstream-variant-2KB
rs5751726 -- 23,759,186(+) aCAAA(A/C)AAAAC upstream-variant-2KB
rs5751727 -- 23,759,282(+) ccacc(C/G)tggcc upstream-variant-2KB
rs5751728 -- 23,759,346(+) ggtag(C/T)gggcg upstream-variant-2KB
rs5760000 -- 23,758,115(+) ctcct(A/G)cctta upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C22orf15 Gene

Variant ID Type Subtype PubMed ID
nsv7350 OTHER Inversion 18451855
esv2724041 CNV Deletion 23290073
nsv526567 CNV Gain 19592680
dgv4906n71 CNV Gain 21882294
nsv914597 CNV Loss 21882294

Variation tolerance for C22orf15 Gene

Gene Damage Index Score: 2.47; 43.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C22orf15 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C22orf15 Gene

Disorders for C22orf15 Gene

Relevant External Links for C22orf15

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C22orf15: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C22orf15 Gene

Publications for C22orf15 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  2. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 67
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67
  5. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 67

Products for C22orf15 Gene

Sources for C22orf15 Gene

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