C22orf15 Gene
protein-coding GIFtS: 36
GCID: GC22P024105
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chromosome 22 open reading frame 15
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Aliases
for C22orf15 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 22 Open Reading Frame 151 2 | | N27C7-31 2 | | Protein N27C7-32 3 | | FLJ365611 | | Uncharacterized Protein C22orf152 |
Export aliases for C22orf15 gene to outside databasesPrevious GC identifers: GC22P022430 GC22P022431 GC22P022435 GC22P007093 |
Summaries
for C22orf15 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C22orf15 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C22orf15 gene promoter:
AML1a LCR-F1 Meis-1b HEN1 FOXJ2 (long isoform) FOXJ2 Meis-1a Pax-4a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C22orf15
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C22orf15 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.23 Ensembl cytogenetic band: 22q11.23 HGNC cytogenetic band: 22q11.23C22orf15 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P024105: view genomic region
(about GC identifiers)
Start:
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24,105,208 bp from pter |
End:
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24,108,050 bp from pter |
Size:
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2,843 bases |
Orientation:
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plus strand |
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Proteins
for C22orf15 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CV015_HUMAN, Q8WYQ4 (See
protein sequence)Recommended Name: Uncharacterized protein C22orf15 Size: 148 amino acids; 16487 Da
Secondary accessions: Q6ICJ7Alternative splicing: 2 isoforms: Q8WYQ4-1 Q8WYQ4-2 Explore the universe of human proteins at neXtProt for C22orf15: NX_Q8WYQ4
C22orf15 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_872326.2
ENSEMBL proteins: ENSP00000384965 ENSP00000305096 ENSP00000372271
Human Recombinant Protein Products:
C22orf15 Antibody Products:
Assay Products for C22orf15: |
Protein
Domains /
Families
for C22orf15 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8WYQ4 |
Function
for C22orf15 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C22orf15 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C22orf15 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: C22orf15 (NM_182520) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C22orf15 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C22orf15 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C22orf15 |
3 GenomeRNAi human phenotypes for C22orf15:
|
Pathways & Interactions
for C22orf15 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C22orf15
|
Drugs & Compounds
for C22orf15 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C22orf15
Search CenterWatch for drugs/clinical trials and news about C22orf15 / CV015
|
Transcripts
for C22orf15 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C22orf15 gene: NM_182520.2 Unigene Cluster for C22orf15: Chromosome 22 open reading frame 15 Hs.116254 [show with all ESTs]Unigene Representative Sequence: AK0938805 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000498542 ENST00000477921(uc002zxv.1 uc011aja.2 uc002zxu.3)
ENST00000402217 ENST00000305199 ENST00000382821
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C22orf15 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C22orf15 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C22orf15 (NM_182520) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C22orf15 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C22orf15 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C22orf15
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C22orf15 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C22orf15 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C22orf15 |
Additional cDNA sequence: AK093880.1 BC113450.1 BC113452.1 CR456371.1 3 DOTS entries: DT.100017779 DT.107543 DT.120634297 18 AceView cDNA sequences: CR456371 BU739625 AI216707 BM982879 AA827701 AK093880 BX110018 BU584544 NM_182520 AX748349 AW001891 AI223426 AA828298 BM713608 BQ027582 CD696490 AI023379 AA628604
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for C22orf15 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b |
|---|
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| SP1: | | | | | | | | | - | | | | | | - | | | | - | | | | | | | | |
| SP2: | | | | | | | | | - | | | | - | | - | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C22orf15
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Expression
for C22orf15 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C22orf15 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCAAAGCCC
About this image
See C22orf15 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C22orf15
SOURCE GeneReport for Unigene cluster: Hs.116254
SABiosciences Custom PCR Arrays for C22orf15
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C22orf15
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C22orf15 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C22orf15 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C22orf15 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C22orf15 |
Orthologs
for C22orf15 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C22orf15 gene from 1/4 species (see all 4) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Gm8675 |
predicted gene 867 |
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|
10 (38.62 cM) 75937723 |
ENSEMBL Gene Tree for C22orf15 (if available)
TreeFam Gene Tree for C22orf15 (if available) |
Paralogs
for C22orf15 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C22orf15 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C22orf15 (24105208 - 24108050 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C22orf15: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C22orf15 |
|
Disorders
/ Diseases
for C22orf15 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C22orf15 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C22orf15 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C22orf15) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
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External Searches for C22orf15 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C22orf15 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C22orf15 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C22orf15 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C22orf15 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C22orf15 gene:
Search GeneIP for patents involving C22orf15
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C22orf15 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C22orf15 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C22orf15 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C22orf15 | | | OriGene Protein Over-expression Lysate for C22orf15 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C22orf15 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C22orf15 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C22orf15 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C22orf15 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C22orf15 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C22orf15 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C22orf15 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C22orf15 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C22orf15 |
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 | | | C22orf15 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C22orf15 |
|  |  |  | | | | Search ThermoFisher Antibodies for C22orf15 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C22orf15 |
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