Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C21orf91 Gene

protein-coding   GIFtS: 46
GCID: GC21M019161

Chromosome 21 Open Reading Frame 91

(Previous name: chromosome 21 open reading frame 38)
(Previous symbols: C21orf38, C21orf14)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Chromosome 21 Open Reading Frame 911 2     Chromosome 21 Open Reading Frame 381
C21orf141 2 3     CSSG12
C21orf381 2 3     EURL2
Cold Sore Susceptibility Gene 11 2     Protein EURL Homolog2
Early Undifferentiated Retina And Lens1 2     C21orf73
YG812 3     

External Ids:    HGNC: 164591   Entrez Gene: 541492   Ensembl: ENSG000001546427   UniProtKB: Q9NYK63   

Export aliases for C21orf91 gene to outside databases

Previous GC identifers: GC21M015826 GC21M018083 GC21M018086 GC21M004550


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for C21orf91 Gene: 
C21orf91 (chromosome 21 open reading frame 91) is a protein-coding gene. Diseases associated with C21orf91 include rabies, and herpes simplex.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000021.8  NC_018932.2  NT_011512.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C21orf91 gene promoter:
         RFX1   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   Arnt   HEN1   E2F-1   E2F   Sox9   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for C21orf91

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C21orf91


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q21.1   Ensembl cytogenetic band:  21q21.1   HGNC cytogenetic band: 21q21.1

C21orf91 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C21orf91 gene location

GeneLoc information about chromosome 21         GeneLoc Exon Structure

GeneLoc location for GC21M019161:  view genomic region     (about GC identifiers)

Start:
19,161,284 bp from pter      End:
19,191,703 bp from pter
Size:
30,420 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: EURL_HUMAN, Q9NYK6 (See protein sequence)
Recommended Name: Protein EURL homolog  
Size: 297 amino acids; 33948 Da
Sequence caution: Sequence=BAB14691.1; Type=Erroneous termination; Positions=164; Note=Translated as Gln;
Secondary accessions: B2RB30 Q96BK9 Q9H8C6
Alternative splicing: 3 isoforms:  Q9NYK6-1   Q9NYK6-2   Q9NYK6-3   

Explore the universe of human proteins at neXtProt for C21orf91: NX_Q9NYK6

Explore proteomics data for C21orf91 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NYK6

  • C21orf91 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    C21orf91 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001093890.1  NP_001093891.1  NP_059143.3  

    ENSEMBL proteins: 
     ENSP00000284881   ENSP00000383404   ENSP00000383403   ENSP00000385566  

    Human Recombinant Protein Products for C21orf91: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for C21orf91
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for C21orf91
    GenScript Custom Purified and Recombinant Proteins Services for C21orf91
    Novus Biologicals C21orf91 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for C21orf91 


    C21orf91 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for C21orf91
    GenScript Custom Superior Antibodies Services for C21orf91
    Novus Biologicals C21orf91 Antibodies
    Search for Antibodies for C21orf91 at Abcam
    Cloud-Clone Corp. Antibodies for C21orf91 
    Search ThermoFisher Antibodies for C21orf91
    LSBio Antibodies in human, mouse, rat for C21orf91 

    Assay Products for C21orf91: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for C21orf91
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for C21orf91
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for C21orf91 
    Cloud-Clone Corp. CLIAs for C21orf91


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR009704 EURL_prot

    Graphical View of Domain Structure for InterPro Entry Q9NYK6

    ProtoNet protein and cluster: Q9NYK6

    1 Blocks protein domain: IPB009704 EURL

    UniProtKB/Swiss-Prot: EURL_HUMAN, Q9NYK6
    Similarity: Belongs to the EURL family


    C21orf91 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for C21orf91 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for C21orf91

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C21orf91 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C21orf91 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C21orf91
    8/74 QIAGEN miScript miRNA Assays for microRNAs that regulate C21orf91 (see all 74):
    hsa-miR-124* hsa-miR-642a hsa-miR-411 hsa-miR-200a hsa-miR-30d hsa-miR-30a hsa-miR-1244 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidC21orf91 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for C21orf91
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C21orf91

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for C21orf91
    Sirion Biotech Customized adenovirus for overexpression of C21orf91

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for C21orf91 (see all 21)
    OriGene ORF clones in mouse, rat for C21orf91
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): C21orf91 (NM_001100421)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C21orf91
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C21orf91
    Sirion Biotech Customized lentivirus for stable overexpression of C21orf91 
                         Customized lentivirus expression plasmids for stable overexpression of C21orf91 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for C21orf91
    Search LifeMap BioReagents cell lines for C21orf91
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf91


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C21orf91

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for C21orf91 (Q9NYK62, 3 ENSP000002848814) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-68232 I2D: score=5 STRING: ENSP00000311695
    GRB2P629933, ENSP000003390074I2D: score=2 STRING: ENSP00000339007
    RAD23BP547273I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C21orf91 (EURL)

    Search CenterWatch for drugs/clinical trials and news about C21orf91 / EURL

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for C21orf91 gene (3 alternative transcripts): 
    NM_001100420.1  NM_001100421.1  NM_017447.3  

    Unigene Cluster for C21orf91:

    Chromosome 21 open reading frame 91
    Hs.293811  [show with all ESTs]
    Unigene Representative Sequence: NM_001100420
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000284881(uc002ykq.4 uc002yko.4 uc002ykp.4) ENST00000400559
    ENST00000400558 ENST00000405964 ENST00000493464 ENST00000482915
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C21orf91
    8/74 QIAGEN miScript miRNA Assays for microRNAs that regulate C21orf91 (see all 74):
    hsa-miR-124* hsa-miR-642a hsa-miR-411 hsa-miR-200a hsa-miR-30d hsa-miR-30a hsa-miR-1244 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidC21orf91 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for C21orf91
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C21orf91
    Clone
    Products:
         
    OriGene clones in human, mouse for C21orf91 (see all 21)
    OriGene ORF clones in mouse, rat for C21orf91
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): C21orf91 (NM_001100421)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C21orf91
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C21orf91
    Sirion Biotech Customized lentivirus for stable overexpression of C21orf91 
                         Customized lentivirus expression plasmids for stable overexpression of C21orf91 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for C21orf91
    OriGene qSTAR qPCR primer pairs in human, mouse for C21orf91
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C21orf91
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C21orf91
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C21orf91

    Additional mRNA sequence: 

    AF239726.1 AJ227876.1 AK023825.1 AK225123.1 AK314471.1 BC015468.2 CR457317.1 CR749496.1 

    9 DOTS entries:

    DT.95110532  DT.413021  DT.95268773  DT.121131289  DT.95268775  DT.95347866  DT.95193440  DT.95262551 
    DT.95350886 

    24/105 AceView cDNA sequences (see all 105):

    AA729027 NM_017447 BQ024690 AI201304 AA608816 AA582707 AI077457 BX099338 
    BC015468 BM719386 BQ434007 AA778701 BU177500 BX088960 AW474520 BI858454 
    AA709292 AW104803 CD652936 AU132076 BM473784 BG537149 BE890677 BX482922 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for C21orf91    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c
    SP1:        -           -     -                                       
    SP2:        -                                                         
    SP3:                    -     -                                       
    SP4:                    -     -                                       
    SP5:                    -     -                 -                     


    ECgene alternative splicing isoforms for C21orf91

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C21orf91 expression in normal human tissues (normalized intensities)      C21orf91 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAACTTTGA
    C21orf91 Expression
    About this image


    C21orf91 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/13 selected tissues (see all 13) fully expand
     
     Limb (Muscoskeletal System)    fully expand to see all 4 entries
             Prechondrocytic Mesenchymal Cells Zeugopod
             limb/hindlimb   
     
     Tooth
             visceral organ/oral region/upper jaw   
     
     Nose (Sensory Organs)    fully expand to see all 2 entries
             sensory organ/nose/nasal cavity   
     
     Testis (Reproductive System)
             sperm   
     
     Gut Tube (Gastrointestinal Tract)
             Foregut

    See C21orf91 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C21orf91

    SOURCE GeneReport for Unigene cluster: Hs.293811
        SABiosciences Custom PCR Arrays for C21orf91
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for C21orf91
    OriGene qSTAR qPCR primer pairs in human, mouse for C21orf91
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C21orf91
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C21orf91
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C21orf91
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf91

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for C21orf91 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia D16Ertd472e1 , 5 DNA segment, Chr 16, ERATO Doi 472, expressed1, 5 83.91(n)1
    82.41(a)1
      16 (45.36 cM)5
    671021  NM_001252438.11  NP_001239367.11 
     785440125 
    chicken
    (Gallus gallus)
    Aves C1H21orf911 chromosome 1 open reading frame, human C21orf91 73.88(n)
    74.91(a)
      395489  NM_204737.1  NP_990068.1 
    lizard
    (Anolis carolinensis)
    Reptilia C21ORF916
    Uncharacterized protein
    67(a)
    1 ↔ 1
    3(153662932-153681002)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.53922 Xenopus laevis transcribed sequence with moderate similarity more 75.26(n)    BX854158.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1100061 zgc:110006 56.21(n)
    54.24(a)
      553573  NM_001020552.1  NP_001018388.1 


    ENSEMBL Gene Tree for C21orf91 (if available)
    TreeFam Gene Tree for C21orf91 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for C21orf91 gene
    2 SIMAP similar genes for C21orf91 using alignment to 2 protein entries:     E7ETB0_HUMAN (see all proteins):
    DKFZp781D1223    EURL

    C21orf91 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/502 SNPs in C21orf91 are shown (see all 502)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 21 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1405246231,2
    --19166925(+) CTAGTA/CTCACT 3 -- int10--------
    rs758447291,2
    --19166978(+) GACTAA/GTATCA 3 -- int10--------
    rs1136386291,2
    C,F--19167148(+) GGAGGC/TTGAGG 3 -- int12Minor allele frequency- T:0.08CSA EA 122
    rs1128131201,2
    C--19167246(+) GTGTAATGGCG  
      CACC
    /-
    ATGAC
    3 -- int11Minor allele frequency- -:0.50CSA 2
    rs568148961,2
    C--19167321(+) AAAAA-/AGGAAA 3 -- int10--------
    rs791547951,2
    --19167338(+) AAAAAG/AGAAAA 3 -- int11Minor allele frequency- A:0.50CSA 2
    rs2011392221,2
    --19167338(+) AAAAA-/GGAAAA 3 -- int10--------
    rs22581191,2
    C,F,O,H--19167479(+) TTCTAT/CGTCAA 3 -- int124Minor allele frequency- C:0.29NS EA NA WA 2785
    rs760244431,2
    C--19167490(+) AATTTG/TTCACA 3 -- int12Minor allele frequency- T:0.08CSA EA 122
    rs787361081,2
    C--19167506(+) AAAAGT/CACTGA 3 -- int12Minor allele frequency- C:0.08CSA EA 122

    HapMap Linkage Disequilibrium report for C21orf91 (19161284 - 19191703 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for C21orf91:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv834055CNV Gain17160897


    Human Gene Mutation Database (HGMD): C21orf91
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing C21orf91
    DNA2.0 Custom Variant and Variant Library Synthesis for C21orf91

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for C21orf91:    About MalaCards
    rabies    herpes simplex


    C21orf91 for disorders           About GeneDecksing


    Export disorders for C21orf91 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C21orf91 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with C21orf91)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. C21orf91 genotypes correlate with herpes simplex labi alis (cold sore) frequency: description of a cold sore susceptibility gene. (PubMed id 22039568)1, 3 Kriesel J.D....Hobbs M.R. (2011)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
    4. Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways. (PubMed id 18624398)1 Wang J....He F. (2008)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    6. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Isolation of a novel cDNA enriched in the undifferentiated chick retina and lens. (PubMed id 12815627)1 Godbout R....Bisgrove D.A. (2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54149 HGNC: 16459 AceView: C21orf91 Ensembl:ENSG00000154642 euGenes: HUgn54149
    ECgene: C21orf91 H-InvDB: C21orf91

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C21orf91 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C21orf91 gene:
    Search GeneIP for patents involving C21orf91

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for C21orf91  
     OriGene qPCR primer pairs and template standards for C21orf91   OriGene Protein Over-expression Lysate for C21orf91  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for C21orf91  
     OriGene qSTAR qPCR primer pairs in human, mouse for C21orf91   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for C21orf91   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for C21orf91   OriGene Custom Protein Services for C21orf91  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C21orf91
     QIAGEN SeqTarget long-range PCR primers for resequencing C21orf91
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C21orf91
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C21orf91
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C21orf91
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C21orf91
     GenScript Custom Purified and Recombinant Proteins Services for C21orf91 GenScript cDNA clones with any tag delivered in your preferred vector for C21orf91
     GenScript Custom Assay Services for C21orf91 GenScript Custom Superior Antibodies Services for C21orf91
     GenScript Custom overexpressing Cell Line Services for C21orf91 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in C21orf91 promoter
     Search Chromatin IP Primers for C21orf91
     RT2 qPCR Primer Assay in human, mouse, rat C21orf91
     Search GNC Networks for C21orf91
     SABiosciences Custom PCR Arrays for C21orf91
     Search Tocris compounds for C21orf91 (EURL)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     C21orf91 antibodies
     C21orf91 lysates
     Search for Antibodies for C21orf91 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for C21orf91
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for C21orf91
     Antibodies for C21orf91
     ELISAs for C21orf91
     CLIAs for C21orf91
     Search LifeMap BioReagents cell lines for C21orf91
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf91
     SwitchGear 3'UTR luciferase reporter plasmids for C21orf91
     Browse SwitchGear Promoter luciferase reporter plasmids for C21orf91
     Search ThermoFisher Antibodies for C21orf91
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C21orf91
     inGenious Targeting Laboratory - Custom generated mouse model solutions for C21orf91
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for C21orf91
    Customized:
     lentivirus for stable overexpression of C21orf91
     lentivirus expression plasmids for stable overexpression of C21orf91
     adenovirus for overexpression of C21orf91
     LSBio Antibodies in human, mouse, rat for C21orf91
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      C21orf91 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4