C21orf90 Gene
protein-coding GIFtS: 30
GCID: GC21P045937
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chromosome 21 open reading frame 90
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Aliases
for C21orf90 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
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| Chromosome 21 Open Reading Frame 901 2 |
Export aliases for C21orf90 gene to outside databasesPrevious GC identifers: GC00U991078 GC21P042529 GC21P044793 GC21P044761 GC21P031311 |
Summaries
for C21orf90 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Genomic Views
for C21orf90 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000021.8 NC_018932.1 NT_011515.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C21orf90 gene promoter:
AML1a FOXL1 PPAR-gamma1 CBF-A CBF-B PPAR-gamma2 CP1A NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for C21orf90
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C21orf90 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 21q22.3 Ensembl cytogenetic band: 21q22.3 HGNC cytogenetic band: 21q22.3C21orf90 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 21 GeneLoc Exon Structure GeneLoc location for GC21P045937: view genomic region
(about GC identifiers)
Start:
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45,937,098 bp from pter |
End:
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45,945,835 bp from pter |
Size:
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8,738 bases |
Orientation:
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plus strand |
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Proteins
for C21orf90 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: CU090_HUMAN, P59090 (See
protein sequence)Recommended Name: Putative uncharacterized protein C21orf90 Size: 65 amino acids; 7097 Da
Caution: Product of a dubious gene prediction. Encoded in intron of TSPEAR
Secondary accessions: Q3MIX8Alternative splicing: 2 isoforms: P59090-1 P59090-2 Explore the universe of human proteins at neXtProt for C21orf90: NX_P59090
C21orf90 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000333592 ENSP00000346295
Human Recombinant Protein Products:
C21orf90 Antibody Products:
Assay Products for C21orf90: |
Protein
Domains /
Families
for C21orf90 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: P59090 |
Function
for C21orf90 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf90 |
1 GenomeRNAi human phenotype for C21orf90:
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Pathways & Interactions
for C21orf90 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C21orf90
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Drugs & Compounds
for C21orf90 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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 Browse Tocris compounds for C21orf90
Search CenterWatch for drugs/clinical trials and news about C21orf90 / CU090 
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Transcripts
for C21orf90 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for C21orf90 gene: NM_153204.1 Unigene Cluster for C21orf90: Chromosome 21 open reading frame 90 Hs.592163 [show with all ESTs]Unigene Representative Sequence: BC0645173 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000330490(uc002zff.4 uc002zfg.4) ENST00000354333 ENST00000465978
Additional cDNA sequence: AF426269.1 AF426270.1 BC016690.2 BC064517.1 BC101650.1 BC101654.1 NR_026547.1 NR_026548.1 4 DOTS entries: DT.101964283 DT.40262625 DT.307376 DT.121134152 14 AceView cDNA sequences: AF426270 BC064517 BC016690 AI033949 NM_153204 AF426269 AW301075 BE384098 R06761 R06810 BF125729 AA009550 T83849 AW070381
GeneLoc Exon Structure
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Expression
for C21orf90 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C21orf90 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCTACCTGC
About this image
See C21orf90 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C21orf90
SOURCE GeneReport for Unigene cluster: Hs.592163
UniProtKB/Swiss-Prot: CU090_HUMAN, P59090Tissue specificity: Widely expressed. Not expressed in liver and muscle
SABiosciences Custom PCR Arrays for C21orf90
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C21orf90 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C21orf90 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C21orf90 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf90 |
Orthologs
for C21orf90 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for C21orf90 (if available)
TreeFam Gene Tree for C21orf90 (if available) |
Paralogs
for C21orf90 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for C21orf90 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C21orf90
1 CNV: 7327 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C21orf90 |
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Disorders
/ Diseases
for C21orf90 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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Publications
for C21orf90 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for C21orf90 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C21orf90) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Nineteen additional unpredicted transcripts from human chromosome 21. (PubMed id 12036297)1, 2, 3 Reymond A....Antonarakis S.E. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- The DNA sequence of human chromosome 21. (PubMed id 10830953)2 Hattori M....Yaspo M.L. (2000)
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External Searches for C21orf90 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing C21orf90 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing C21orf90 gene
(According to HUGE)
About This Section
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Specialized Databases showing C21orf90 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for C21orf90 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for C21orf90 gene:
Search GeneIP for patents involving C21orf90
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C21orf90 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C21orf90 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C21orf90 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C21orf90 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C21orf90 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C21orf90 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C21orf90 |
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 | | | C21orf90 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf90 |
|  |  |  | | | | Search ThermoFisher Antibodies for C21orf90 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C21orf90 |
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