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C21orf82 Gene

RNA gene   GIFtS: 27

GC21P035552
chromosome 21 open reading frame 82
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases & Descriptions
chromosome 21 open reading frame 821 2
FLJ353852
MGC1382012

External Ids:    HGNC: 164141   Entrez Gene: 1140362   Ensembl: ENSG000002274567   UniProtKB: P590363   

Search outside databases for aliases for C21orf82 gene

Previous GC identifers: GC00U991073 GC21P032213 GC21P034473 GC21P034474 GC21U900215

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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  --
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
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Regulatory elements:
"" Search SABiosciences Regulatory transcription factor binding sites for C21orf82 ""

Epigenetics:
"" Search SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for C21orf82 ""

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.11   Ensembl cytogenetic band:  21q22.11   HGNC chromosome: 21

C21orf82 Gene in genomic location: bands according to Ensembl, locations according to "" (and/or Entrez Gene and/or Ensembl if different)
""

GeneLoc gene densities for chromosome 21         GeneLoc Exon Structure

GeneLoc location for GC21P035552:  view genomic region     (about GC identifiers)

Start:
35,552,978 bp from pter
End:
35,562,220 bp from pter
Size:
9,243 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000021.8  NT_011512.11  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
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UniProtKB/Swiss-Prot: CU082_HUMAN, P59036 (See protein sequence)
Recommended Name: Uncharacterized protein C21orf82  
Size: 64 amino acids; 7298 Da
Secondary accessions: Q52LY1


Human Recombinant Proteins 

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Antibodies for C21orf82: 
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Assays for C21orf82: 
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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: P59036

(According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
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Inhib.
RNA:
""Browse for Gene Knock-down Tools from Millipore
""Browse Abnova for Chimera RNAi Products
"" Origene 29mer shRNA kits in GFP-retroviral vector (see all 2): C21orf82
Origene shRNA RFP (see all 2): C21orf82
Origene basic RS shRNA (see all 2): C21orf82

""Applied Biosystems Silencer® siRNAs for C21orf82
""Browse siRNA at Sigma-Aldrich
Sigma-Aldrich shRNA for C21orf82
Explore Sigma-Aldrich super-pooled esiRNAs
Clones:""Browse Clones for the Expression of Recombinant Proteins Available from Millipore
""Browse iPSC Reprogramming Factors at Sigma-Aldrich
""Browse Origene untagged/tagged cDNA clones in CMV expression vector
""Browse Sino Biological Human cDNA Clones  ""
(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
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"" Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C21orf82
(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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"" Browse drugs & compounds from Enzo Life Sciences
""Browse Small Molecules at Sigma-Aldrich

"" Browse Tocris compounds for C21orf82

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
Expression Assays from Applied Biosystems)
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Inhib.
RNA:
""Browse for Gene Knock-down Tools from Millipore
""Browse Abnova for Chimera RNAi Products
"" Origene 29mer shRNA kits in GFP-retroviral vector (see all 2): C21orf82
Origene shRNA RFP (see all 2): C21orf82
Origene basic RS shRNA (see all 2): C21orf82

""Browse siRNA at Sigma-Aldrich
Sigma-Aldrich shRNA for C21orf82
Explore Sigma-Aldrich super-pooled esiRNAs

microRNA:""Search SABiosciences for microRNAs that regulate C21orf82: ""

Clones:""Browse Origene untagged/tagged cDNA clones in CMV expression vector
Primers:""Browse Origene genome-wide validated SYBR primer pairs
""SABiosciences RT2 qPCR Primer Assay for C21orf82: PPH13266A ""

Additional cDNA sequence: 

AF426258.1 AK092704.1 BC093749.1 BC111996.1 

3 DOTS entries:

DT.40129840  DT.97789274  DT.100688983 

18 AceView cDNA sequences:

BM695339 AK092704 AW139993 AF426258 Z36963 BF477347 BX098800 AI471119 
AI919214 AI027483 BM664988 CD512568 AI423249 W61117 W65378 BI002334 
N79996 AA007432 

"" highest scoring ESTs for C21orf82:

BM664988 NM_153751 W61117 W65378 AI423249 AI471119 N79996 AA007432 AF426258 AI027483 

Unigene Cluster for C21orf82:

Chromosome 21 open reading frame 82
Hs.720230  [show with all ESTs]
Unigene Representative Sequence: AK092704


GeneLoc Exon Structure

4 Ensembl transcripts including schematic representations:
ENST00000430922  ENST00000419881  ENST00000416145  ENST00000428914  
(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
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C21orf82 expression in normal and diseased human tissues

"" Applied Biosystems TaqMan ® Gene Expression Assays for C21orf82

1""  / 2""  / 3""

3 probe-sets matching C21orf82 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
84085_at2, 3 U95-E 1 0.38 1.00 1.00 1.00 AI423249 0.60 0.60 0.60 1
237326_at2, 3 U133-B 1 0.27 1.00 -- -- AI423249 0.60 0.60 0.60 1
237326_at2 U133Plus2 1 0.27 1.00 -- -- -- -- -- -- --
About this table

"" C21orf82 for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.720230

UniProtKB/Swiss-Prot: CU082_HUMAN, P59036
Tissue specificity: Widely expressed; not found in breast

Primers:""Browse Origene genome-wide validated SYBR primer pairs ""
""SABiosciences RT2 qPCR Primer Assay for C21orf82: PPH13266A ""
(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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ENSEMBL Gene Tree for C21orf82
(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
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(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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6 PubMed articles for C21orf82 gene:
(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)
(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 114036 HGNC: 16414 AceView: C21orf82 Ensembl:ENSG00000227456 euGenes: HUgn114036
ECgene: C21orf82 H-InvDB: C21orf82
(According to HUGE)
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  --
(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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  --
(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
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Patent Information for C21orf82 gene: ""
Search GeneIP for patents involving C21orf82

GeneCards and IP: ""
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search


(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Novus Biologicals,
Epitomics, Sigma-Aldrich, R&D Systems, SABiosciences, Millipore, Abnova,
Clones available from OriGene, Sigma-Aldrich, Sino Biological, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience)
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""
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Products for C21orf82:
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 "" Free SNP selection tool

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"" Lentivirus-delivered shRNAs for C21orf82"" Browse small molecules at Sigma-Aldrich
"" "Your Favorite Gene" Pathways"" Browse ELISAs at Sigma-Aldrich
"" Browse iPSC Reprogramming Factors at Sigma-Aldrichfeedback


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"" Recombinant & Natural Proteins  

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"" Search Tocris compounds for C21orf82
"" Search Regulatory tfbs for C21orf82
"" Search Chromatin IP Primers for C21orf82
"" Search DNA Methylation qPCR Primer Assays for C21orf82
"" RT2 qPCR Primer Assay for C21orf82
"" Search GNC Networks for C21orf82
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