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Aliases for C21orf62-AS1 Gene

Subcategory (RNA class) for C21orf62-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for C21orf62-AS1 Gene

  • C21orf62 Antisense RNA 1 2 3 4 5
  • C21orf49 3 4
  • Chromosome 21 Open Reading Frame 49 2
  • C21orf62 Antisense Gene Protein 1 4

External Ids for C21orf62-AS1 Gene

Previous HGNC Symbols for C21orf62-AS1 Gene

  • C21orf49

Summaries for C21orf62-AS1 Gene

GeneCards Summary for C21orf62-AS1 Gene

C21orf62-AS1 (C21orf62 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C21orf62-AS1 Gene

Genomics for C21orf62-AS1 Gene

Regulatory Elements for C21orf62-AS1 Gene

Enhancers for C21orf62-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21F032726 1.1 ENCODE 12.5 -44.3 -44315 2.7 HDGF PKNOX1 ARNT CREB3L1 ZFP64 ARID4B SIN3A YY1 SLC30A9 ZNF143 C21orf62-AS1 PAXBP1 EVA1C SYNJ1 PAXBP1-AS1 ENSG00000238220
GH21F032702 1.1 Ensembl ENCODE 10.6 -69.1 -69118 0.8 FEZF1 ZNF664 ZNF366 SCRT2 PRDM10 ZNF600 ZNF639 ZNF362 OVOL3 TSHZ1 PAXBP1 C21orf62-AS1 SNORA80A RPS5P3 TMEM50B ENSG00000231355 SYNJ1 ENSG00000238220
GH21F032816 1 ENCODE 10.7 +45.2 45230 2.4 ATF1 PKNOX1 ARNT CREB3L1 ZNF766 GATA2 FOS JUNB NCOA1 MEF2D PAXBP1 C21orf62-AS1 SYNJ1 C21orf62 ENSG00000224427
GH21F032712 0.9 Ensembl ENCODE 10.9 -59.9 -59900 0.4 SP1 MTA2 CBX5 ZNF366 BHLHE40 CBFB MLLT1 TBX21 PAXBP1 C21orf62-AS1 TCP10L SYNJ1 ENSG00000238220
GH21F032818 0.9 ENCODE 10.7 +47.5 47529 1.8 ATF1 CBX3 ARNT CREB3L1 GATA2 FOS EGR2 SMARCA5 NCOA1 ZEB2 C21orf62-AS1 PAXBP1 SYNJ1 C21orf62 ENSG00000224427
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C21orf62-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for C21orf62-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001566277 -700 3601 CREB3L1 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF263 SP3

Genomic Location for C21orf62-AS1 Gene

Chromosome:
21
Start:
32,772,100 bp from pter
End:
32,893,735 bp from pter
Size:
121,636 bases
Orientation:
Plus strand

Genomic View for C21orf62-AS1 Gene

Genes around C21orf62-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C21orf62-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C21orf62-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C21orf62-AS1 Gene

Proteins for C21orf62-AS1 Gene

  • Protein details for C21orf62-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q17RA5-CMAS1_HUMAN
    Recommended name:
    Putative uncharacterized protein C21orf62-AS1
    Protein Accession:
    Q17RA5

    Protein attributes for C21orf62-AS1 Gene

    Size:
    79 amino acids
    Molecular mass:
    8913 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C21orf62-AS1 Gene

Post-translational modifications for C21orf62-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C21orf62-AS1 Gene

Domains & Families for C21orf62-AS1 Gene

Protein Domains for C21orf62-AS1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C21orf62-AS1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C21orf62-AS1 Gene

Function for C21orf62-AS1 Gene

genes like me logo Genes that share phenotypes with C21orf62-AS1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C21orf62-AS1 Gene

Localization for C21orf62-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C21orf62-AS1 gene
Compartment Confidence
extracellular 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C21orf62-AS1 Gene

Pathways & Interactions for C21orf62-AS1 Gene

SuperPathways for C21orf62-AS1 Gene

No Data Available

Interacting Proteins for C21orf62-AS1 Gene

Gene Ontology (GO) - Biological Process for C21orf62-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C21orf62-AS1 Gene

Transcripts for C21orf62-AS1 Gene

mRNA/cDNA for C21orf62-AS1 Gene

(1) REFSEQ mRNAs :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for C21orf62-AS1 Gene

No ASD Table

Relevant External Links for C21orf62-AS1 Gene

GeneLoc Exon Structure for
C21orf62-AS1
ECgene alternative splicing isoforms for
C21orf62-AS1

Expression for C21orf62-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C21orf62-AS1 Gene

genes like me logo Genes that share expression patterns with C21orf62-AS1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C21orf62-AS1 Gene

Orthologs for C21orf62-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C21orf62-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C21orf49 35
  • 99 (a)
OneToOne
Species where no ortholog for C21orf62-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C21orf62-AS1 Gene

ENSEMBL:
Gene Tree for C21orf62-AS1 (if available)
TreeFam:
Gene Tree for C21orf62-AS1 (if available)

Paralogs for C21orf62-AS1 Gene

No data available for Paralogs for C21orf62-AS1 Gene

Variants for C21orf62-AS1 Gene

Sequence variations from dbSNP and Humsavar for C21orf62-AS1 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs10211969 -- 32,787,717(+) CCCTC(A/T)ATTGA intron-variant
rs1054663 -- 32,797,577(+) GTTCT(C/T)TTTCA intron-variant, nc-transcript-variant
rs11088229 -- 32,782,711(+) TGCAC(C/G)CTTTC intron-variant
rs111389923 -- 32,786,947(+) TTGGG(A/G)TAAGA intron-variant
rs111523224 -- 32,788,941(+) GCAAA(G/T)TATGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C21orf62-AS1 Gene

Variant ID Type Subtype PubMed ID
esv2268996 CNV deletion 18987734
esv2665744 CNV deletion 23128226
esv2723346 CNV deletion 23290073
esv2740731 CNV deletion 23290073
esv3646894 CNV loss 21293372
esv3646895 CNV loss 21293372
nsv473538 CNV novel sequence insertion 20440878
nsv481301 CNV novel sequence insertion 20440878
nsv509793 CNV insertion 20534489
nsv834086 CNV loss 17160897

Variation tolerance for C21orf62-AS1 Gene

Gene Damage Index Score: 0.51; 10.99% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C21orf62-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C21orf62-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C21orf62-AS1 Gene

Disorders for C21orf62-AS1 Gene

Relevant External Links for C21orf62-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C21orf62-AS1

No disorders were found for C21orf62-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C21orf62-AS1 Gene

Publications for C21orf62-AS1 Gene

  1. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M. … Yaspo M.-L. (Nature 2000) 3 4 64
  2. Genome-wide association of serum bilirubin levels in Korean population. (PMID: 20639394) Kang T.W. … Kim Y.S. (Hum. Mol. Genet. 2010) 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for C21orf62-AS1 Gene

Sources for C21orf62-AS1 Gene

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