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Aliases for C21orf62-AS1 Gene

Subcategory (RNA class) for C21orf62-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for C21orf62-AS1 Gene

  • C21orf62 Antisense RNA 1 2 3 4 5
  • C21orf49 3 4
  • Chromosome 21 Open Reading Frame 49 2
  • C21orf62 Antisense Gene Protein 1 4

External Ids for C21orf62-AS1 Gene

Previous HGNC Symbols for C21orf62-AS1 Gene

  • C21orf49

Summaries for C21orf62-AS1 Gene

GeneCards Summary for C21orf62-AS1 Gene

C21orf62-AS1 (C21orf62 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for C21orf62-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C21orf62-AS1 Gene

Genomics for C21orf62-AS1 Gene

GeneHancer (GH) Regulatory Elements for C21orf62-AS1 Gene

Promoters and enhancers for C21orf62-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21I032769 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE 563.8 -0.7 -747 3.9 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF416 ZNF143 ZNF263 PAXBP1 C21orf62-AS1 TMEM50B SON DONSON C21orf59 EVA1C MIS18A-AS1 URB1 MIS18A
GH21I032726 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 12.5 -44.3 -44334 2.7 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A YY1 SLC30A9 POLR2B ZNF213 SYNJ1 PAXBP1-AS1 SCAF4 PAXBP1 SON MIS18A EVA1C TMEM50B C21orf62-AS1 GART
GH21I033228 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 10.2 +459.2 459167 5.1 HDGF PKNOX1 ATF1 SMAD1 SIN3A GLI4 ZNF2 IRF4 ZNF121 GLIS2 IFNAR2 PAXBP1 TMEM50B IL10RB MIS18A C21orf62-AS1 DONSON ENSG00000249624
GH21I033201 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.2 +431.9 431862 4.5 HDGF PKNOX1 SMAD1 SIN3A DMAP1 ZNF48 YY1 ATF7 ZNF548 FOS SON PAXBP1 TMEM50B EVA1C GART DONSON IFNAR2 IFNGR2 URB1 C21orf59
GH21I032492 Enhancer 1.3 Ensembl ENCODE dbSUPER 13.1 -277.4 -277420 4.6 PKNOX1 ZNF493 ZNF529 ZFP64 FEZF1 BATF ZNF48 RFX5 ZNF213 EGR1 PAXBP1 TMEM50B SCAF4 EVA1C C21orf59 URB1 MIS18A PAXBP1-AS1 C21orf62-AS1 ENSG00000238390
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around C21orf62-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for C21orf62-AS1 Gene

Genomic Locations for C21orf62-AS1 Gene
chr21:32,772,100-32,893,735
(GRCh38/hg38)
Size:
121,636 bases
Orientation:
Plus strand
chr21:34,144,411-34,266,043
(GRCh37/hg19)

Genomic View for C21orf62-AS1 Gene

Genes around C21orf62-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C21orf62-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C21orf62-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C21orf62-AS1 Gene

Proteins for C21orf62-AS1 Gene

  • Protein details for C21orf62-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q17RA5-CMAS1_HUMAN
    Recommended name:
    Putative uncharacterized protein C21orf62-AS1
    Protein Accession:
    Q17RA5

    Protein attributes for C21orf62-AS1 Gene

    Size:
    79 amino acids
    Molecular mass:
    8913 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C21orf62-AS1 Gene

Post-translational modifications for C21orf62-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C21orf62-AS1 Gene

Domains & Families for C21orf62-AS1 Gene

Protein Domains for C21orf62-AS1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C21orf62-AS1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C21orf62-AS1 Gene

Function for C21orf62-AS1 Gene

Phenotypes From GWAS Catalog for C21orf62-AS1 Gene

genes like me logo Genes that share phenotypes with C21orf62-AS1: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C21orf62-AS1 Gene

Localization for C21orf62-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C21orf62-AS1 gene
Compartment Confidence
extracellular 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C21orf62-AS1 Gene

Pathways & Interactions for C21orf62-AS1 Gene

SuperPathways for C21orf62-AS1 Gene

No Data Available

Interacting Proteins for C21orf62-AS1 Gene

Gene Ontology (GO) - Biological Process for C21orf62-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C21orf62-AS1 Gene

Drugs & Compounds for C21orf62-AS1 Gene

No Compound Related Data Available

Transcripts for C21orf62-AS1 Gene

mRNA/cDNA for C21orf62-AS1 Gene

(1) REFSEQ mRNAs :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C21orf62-AS1 Gene

No ASD Table

Relevant External Links for C21orf62-AS1 Gene

GeneLoc Exon Structure for
C21orf62-AS1
ECgene alternative splicing isoforms for
C21orf62-AS1

Expression for C21orf62-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C21orf62-AS1 Gene

genes like me logo Genes that share expression patterns with C21orf62-AS1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C21orf62-AS1 Gene

Orthologs for C21orf62-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C21orf62-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C21orf49 34
  • 99 (a)
OneToOne
Species where no ortholog for C21orf62-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C21orf62-AS1 Gene

ENSEMBL:
Gene Tree for C21orf62-AS1 (if available)
TreeFam:
Gene Tree for C21orf62-AS1 (if available)

Paralogs for C21orf62-AS1 Gene

No data available for Paralogs for C21orf62-AS1 Gene

Variants for C21orf62-AS1 Gene

Sequence variations from dbSNP and Humsavar for C21orf62-AS1 Gene

SNP ID Clin Chr 21 pos Variation AA Info Type
rs1000098758 -- 32,773,713(+) A/G intron_variant
rs1000102137 -- 32,795,026(+) T/A intron_variant
rs1000264859 -- 32,785,779(+) T/C intron_variant
rs1000299445 -- 32,777,873(+) A/C intron_variant
rs1000462200 -- 32,772,134(+) CAGAC/C non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for C21orf62-AS1 Gene

Variant ID Type Subtype PubMed ID
esv2268996 CNV deletion 18987734
esv2665744 CNV deletion 23128226
esv2723346 CNV deletion 23290073
esv2740731 CNV deletion 23290073
esv3646894 CNV loss 21293372
esv3646895 CNV loss 21293372
nsv473538 CNV novel sequence insertion 20440878
nsv481301 CNV novel sequence insertion 20440878
nsv509793 CNV insertion 20534489
nsv834086 CNV loss 17160897

Variation tolerance for C21orf62-AS1 Gene

Gene Damage Index Score: 0.51; 10.99% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for C21orf62-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C21orf62-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C21orf62-AS1 Gene

Disorders for C21orf62-AS1 Gene

Additional Disease Information for C21orf62-AS1

No disorders were found for C21orf62-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C21orf62-AS1 Gene

Publications for C21orf62-AS1 Gene

  1. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M … Chromosome 21 mapping and sequencing consortium (Nature 2000) 3 4 58
  2. Genome-wide association of serum bilirubin levels in Korean population. (PMID: 20639394) Kang TW … Kim YS (Human molecular genetics 2010) 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for C21orf62-AS1 Gene

Sources for C21orf62-AS1 Gene

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