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Aliases for C21orf62 Gene

Aliases for C21orf62 Gene

  • Chromosome 21 Open Reading Frame 62 2 3
  • C21orf120 3 4
  • B37 3 4
  • Chromosome 21 Open Reading Frame 120 2
  • Uncharacterized Protein C21orf62 3
  • PRED81 3

External Ids for C21orf62 Gene

Previous HGNC Symbols for C21orf62 Gene

  • C21orf120

Previous GeneCards Identifiers for C21orf62 Gene

  • GC21M030743
  • GC21M033086
  • GC21M033087
  • GC21M034163
  • GC21M019572

Summaries for C21orf62 Gene

GeneCards Summary for C21orf62 Gene

C21orf62 (Chromosome 21 Open Reading Frame 62) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C21orf62 Gene

Genomics for C21orf62 Gene

Regulatory Elements for C21orf62 Gene

Genomic Location for C21orf62 Gene

Start:
32,790,673 bp from pter
End:
32,813,743 bp from pter
Size:
23,071 bases
Orientation:
Minus strand

Genomic View for C21orf62 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C21orf62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C21orf62 Gene

Proteins for C21orf62 Gene

  • Protein details for C21orf62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NYP8-CU062_HUMAN
    Recommended name:
    Uncharacterized protein C21orf62
    Protein Accession:
    Q9NYP8
    Secondary Accessions:
    • A8K4L8

    Protein attributes for C21orf62 Gene

    Size:
    219 amino acids
    Molecular mass:
    24886 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF72946.1; Type=Frameshift; Positions=181; Evidence={ECO:0000305};

neXtProt entry for C21orf62 Gene

Proteomics data for C21orf62 Gene at MOPED

Post-translational modifications for C21orf62 Gene

No Post-translational modifications

Other Protein References for C21orf62 Gene

No data available for DME Specific Peptides for C21orf62 Gene

Domains for C21orf62 Gene

Protein Domains for C21orf62 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C21orf62 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C21orf62: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C21orf62 Gene

Function for C21orf62 Gene

Gene Ontology (GO) - Molecular Function for C21orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with C21orf62: view

Phenotypes for C21orf62 Gene

MGI mutant phenotypes for C21orf62:
inferred from 1 alleles
GenomeRNAi human phenotypes for C21orf62:
genes like me logo Genes that share phenotypes with C21orf62: view

Animal Model Products

CRISPR Products

miRNA for C21orf62 Gene

miRTarBase miRNAs that target C21orf62

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for C21orf62 Gene

Localization for C21orf62 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C21orf62 Gene COMPARTMENTS Subcellular localization image for C21orf62 gene
Compartment Confidence
extracellular 2
cytosol 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C21orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with C21orf62: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C21orf62 Gene

Pathways for C21orf62 Gene

SuperPathways for C21orf62 Gene

No Data Available

Interacting Proteins for C21orf62 Gene

Gene Ontology (GO) - Biological Process for C21orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with C21orf62: view

No data available for Pathways by source for C21orf62 Gene

Transcripts for C21orf62 Gene

Unigene Clusters for C21orf62 Gene

Chromosome 21 open reading frame 62:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C21orf62

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C21orf62

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C21orf62 Gene

No ASD Table

Relevant External Links for C21orf62 Gene

GeneLoc Exon Structure for
C21orf62
ECgene alternative splicing isoforms for
C21orf62

Expression for C21orf62 Gene

mRNA expression in normal human tissues for C21orf62 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C21orf62 Gene

This gene is overexpressed in Pituitary (10.5), Ovary (9.1), Kidney - Cortex (4.4), and Brain - Hypothalamus (4.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C21orf62 Gene

SOURCE GeneReport for Unigene cluster for C21orf62 Gene Hs.517235

genes like me logo Genes that share expressions with C21orf62: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for C21orf62 Gene

Orthologs for C21orf62 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C21orf62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C21H21orf62 35
  • 98.78 (n)
  • 97.72 (a)
C21orf62 36
  • 77 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C1H21orf62 35
  • 84.86 (n)
  • 78.9 (a)
C21orf62 36
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C31H21orf62 35
  • 84.02 (n)
  • 79.91 (a)
C31H21orf62 36
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4932438H23Rik 35
  • 79.4 (n)
  • 70.28 (a)
4932438H23Rik 16
4932438H23Rik 36
  • 64 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C21orf62 36
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1562726 35
  • 78.67 (n)
  • 71.09 (a)
chicken
(Gallus gallus)
Aves C1H21ORF62 35
  • 63.51 (n)
  • 57.82 (a)
C21orf62 36
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C21orf62 36
  • 42 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c21orf62 35
  • 59.08 (n)
  • 51.98 (a)
Species with no ortholog for C21orf62:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C21orf62 Gene

ENSEMBL:
Gene Tree for C21orf62 (if available)
TreeFam:
Gene Tree for C21orf62 (if available)

Paralogs for C21orf62 Gene

No data available for Paralogs for C21orf62 Gene

Variants for C21orf62 Gene

Sequence variations from dbSNP and Humsavar for C21orf62 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type MAF
rs963636 -- 32,803,255(+) TAAAC(C/T)GACAC intron-variant
rs1034316 -- 32,804,555(+) GAGTC(A/C)TAGTG intron-variant
rs1892578 -- 32,800,493(+) TTTAA(C/T)AATCA intron-variant
rs1892579 -- 32,800,614(+) AGTTC(C/G)AGACC intron-variant
rs1892580 -- 32,806,186(+) AAGGG(C/T)GACAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C21orf62 Gene

Variant ID Type Subtype PubMed ID
nsv834086 CNV Loss 17160897
nsv509793 CNV Insertion 20534489

Relevant External Links for C21orf62 Gene

HapMap Linkage Disequilibrium report
C21orf62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C21orf62 Gene

Disorders for C21orf62 Gene

Relevant External Links for C21orf62

Genetic Association Database (GAD)
C21orf62
genes like me logo Genes that share disorders with C21orf62: view

No data available for UniProtKB/Swiss-Prot for C21orf62 Gene

Publications for C21orf62 Gene

  1. Criteria for gene identification and features of genome organization: analysis of 6.5 Mb of DNA sequence from human chromosome 21. (PMID: 10773462) Slavov D. … Gardiner K. (Gene 2000) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  3. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M. … Yaspo M.-L. (Nature 2000) 4
  4. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PMID: 17903300) Fox C.S. … Atwood L.D. (BMC Med. Genet. 2007) 48
  5. Genome-wide association of serum bilirubin levels in Korean population. (PMID: 20639394) Kang T.W. … Kim Y.S. (Hum. Mol. Genet. 2010) 3

Products for C21orf62 Gene

Sources for C21orf62 Gene

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