Aliases for C21orf59 Gene
External Ids for C21orf59 Gene
Previous HGNC Symbols for C21orf59 Gene
Previous GeneCards Identifiers for C21orf59 Gene
This gene encodes a protein that plays a critical role in dynein arm assembly and motile cilia function. Mutations in this gene result in primary ciliary dyskinesia. Naturally occuring readthrough transcription occurs from this locus to the downstream t-complex 10 like (TCP10L) gene. [provided by RefSeq, Apr 2017]
GeneCards Summary for C21orf59 Gene
C21orf59 (Chromosome 21 Open Reading Frame 59) is a Protein Coding gene. Diseases associated with C21orf59 include Ciliary Dyskinesia, Primary, 26 and Primary Ciliary Dyskinesia 26: C21orf59-Related Primary Ciliary Dyskinesia. An important paralog of this gene is ENSG00000265590.
UniProtKB/Swiss-Prot for C21orf59 Gene
May play a role in motile cilia function, possibly by acting on dynein arm assembly.