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C21orf58 Gene

protein-coding   GIFtS: 42
GCID: GC21M047720

Chromosome 21 Open Reading Frame 58

  Search for C21orf58
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, 15RNAdb, and/or 11Nature:405,311-319 and CroW21)
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Aliases
Chromosome 21 Open Reading Frame 581 2
Spliced ESTs Z25278,AA82526611
Uncharacterized Protein C21orf582

External Ids:    HGNC: 13001   Entrez Gene: 540582   Ensembl: ENSG000001602987   UniProtKB: P585053   

Export aliases for C21orf58 gene to outside databases

Previous GC identifers: GC21M044226 GC21M046576 GC21M046577 GC21M046545 GC21M033104


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for C21orf58 Gene:
C21orf58 (chromosome 21 open reading frame 58) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics, Whole Chromsome Sequence According to Nature (Cited Here with Permission):405,311-319 and CroW21)
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RefSeq DNA sequence at NCBI GenBank:
NC_000021.8  NT_011512.12  NC_018932.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the C21orf58 gene promoter:
         HOXA9B   HOXA9   STAT5B   Nkx2-5   POU6F1 (c2)   Roaz   AREB6   Meis-1a   Meis-1   ATF6   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

   Search Chromatin IP Primers for C21orf58

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C21orf58


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.3   Ensembl cytogenetic band:  21q22.3   HGNC cytogenetic band: 21q22.3
Nature(405: 311-319) cytogenetic band:   21q22.3
C21orf58 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C21orf58 gene location
GeneLoc information about chromosome 21         GeneLoc Exon Structure

(about GC identifiers)
GC21M047720:   GeneLoc Nature:405,311-319
Start:
47,720,095 bp from pter       33,227,047 bp from centromere
End:
47,743,789 bp from pter 33,244,524 bp from centromere
Size:
23,695 bases 17,478 bases
Orientation:
minus strand minus strand

genomic clones: CTD2308H15


(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CU058_HUMAN, P58505 (See protein sequence)
Recommended Name: Uncharacterized protein C21orf58  
Size: 322 amino acids; 35003 Da
Sequence caution: Sequence=AAK72408.1; Type=Erroneous initiation; Sequence=AAK72409.1; Type=Erroneous initiation;
Secondary accessions: B3KPI1
Alternative splicing: 2 isoforms:  P58505-1   P58505-2   

Explore the universe of human proteins at neXtProt for C21orf58: NX_P58505

Explore proteomics data for C21orf58 at MOPED


See C21orf58 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (5 alternative transcripts): 
NP_001273391.1  NP_001273392.1  NP_001273405.1  NP_001273406.1  NP_478060.2  

ENSEMBL proteins: 
 ENSP00000431312   ENSP00000380799   ENSP00000402356   ENSP00000380798   ENSP00000291691  
 ENSP00000380796   ENSP00000380797   ENSP00000390432   ENSP00000380801  

C21orf58 Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for C21orf58

 
Search eBioscience for Proteins for C21orf58 

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Abcam antibodies for C21orf58
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LSBio Antibodies in human, mouse, rat for C21orf58

C21orf58 Assay Products:

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Cloud-Clone Corp. ELISAs for C21orf58
Cloud-Clone Corp. CLIAs for C21orf58
Search eBioscience for ELISAs for C21orf58 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR027904 DUF4587

Graphical View of Domain Structure for InterPro Entry P58505

ProtoNet protein and cluster: P58505


Find genes that share domains with C21orf58           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Phenotypes:
     1 GenomeRNAi human phenotype for C21orf58:
 Increased gamma-H2AX phosphory 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C21orf58
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for C21orf58

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C21orf58
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C21orf58

miRNA
Products:
    
miRTarBase miRNAs that target C21orf58:
hsa-mir-107 (MIRT048290), hsa-mir-149-5p (MIRT045479)

Block miRNA regulation of human, mouse, rat C21orf58 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate C21orf58
SwitchGear 3'UTR luciferase reporter plasmidC21orf58 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for C21orf58
Predesigned siRNA for gene silencing in human, mouse, rat C21orf58

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for C21orf58

Clone
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OriGene clones in human, mouse for C21orf58 (see all 7)
OriGene ORF clones in mouse, rat for C21orf58
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: C21orf58 (NM_058180)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for C21orf58
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C21orf58

Cell Line
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GenScript Custom overexpressing Cell Line Services for C21orf58
Browse ESI BIO Cell Lines and PureStem Progenitors for C21orf58 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf58


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
mitochondrion3
nucleus3

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for C21orf58
Interactions:

    Search GeneGlobe Interaction Network for C21orf58

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for C21orf58 (P585053 ENSP000002916914) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
GRB2P629933, ENSP000003390074I2D: score=2 STRING: ENSP00000339007
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for C21orf58 (CU058)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for C21orf58 gene (6 alternative transcripts): 
NM_199071.2  NM_001286462.1  NM_001286463.1  NM_001286476.1  NM_001286477.1  NM_058180.4  

Unigene Cluster for C21orf58:

Chromosome 21 open reading frame 58
Hs.236572  [show with all ESTs]
Unigene Representative Sequence: NM_058180
11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000491666 ENST00000397683(uc002ziz.3 uc002zja.3) ENST00000417060
ENST00000397682(uc010gqj.2) ENST00000291691(uc002zjf.3) ENST00000397679(uc002zjc.3)
ENST00000397680(uc011afx.2) ENST00000472607 ENST00000445935 ENST00000475776
ENST00000397685(uc002zjg.1)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat C21orf58 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate C21orf58
SwitchGear 3'UTR luciferase reporter plasmidC21orf58 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for C21orf58
Predesigned siRNA for gene silencing in human, mouse, rat C21orf58
Clone
Products:
     
OriGene clones in human, mouse for C21orf58 (see all 7)
OriGene ORF clones in mouse, rat for C21orf58
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: C21orf58 (NM_058180)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for C21orf58
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C21orf58
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for C21orf58
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat C21orf58
  QuantiTect SYBR Green Assays in human, mouse, rat C21orf58
  QuantiFast Probe-based Assays in human, mouse, rat C21orf58

Additional mRNA sequence: 

AK056387.1 AK096641.1 AK098098.1 AY039243.1 AY039244.1 BC026042.1 BC028934.1 BC031638.1 
BC044223.1 BC067876.1 BC121007.1 BC121008.1 

11 DOTS entries:

DT.100780908  DT.92033544  DT.40225837  DT.95369017  DT.40271356  DT.40261613  DT.430998  DT.99933439 
DT.121142349  DT.92415775  DT.91689356 

Selected AceView cDNA sequences (see all 48):

AK096641 CB856841 BU789102 BI223146 AI859860 BU789364 BM504331 BC026042 
BM504105 BE792433 CA424954 CB305953 BU660253 BX405373 AK098098 BE019649 
AY039244 BC028934 AI979100 BX283720 AY039243 BC044223 BI756723 BM802252 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for C21orf58 (see all 11)    About this scheme

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13
SP1:              -     -     -     -     -                             -           -           -                 -                                 
SP2:                                                                                -                             -                                 
SP3:                                                                    -           -           -                 -                       -         
SP4:                                                                    -           -           -                 -                                 
SP5:              -     -     -     -                                   -                                                                           


ECgene alternative splicing isoforms for C21orf58

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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C21orf58 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AGCAACCTCG
C21orf58 Expression
About this image

C21orf58 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

C21orf58 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.236572

UniProtKB/Swiss-Prot: CU058_HUMAN, P58505
Tissue specificity: Expressed in skin and fetal lung

    Custom PCR Arrays for C21orf58
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QuantiFast Probe-based Assays in human, mouse, rat C21orf58
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf58

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for C21orf58 gene from Selected species (see all 9)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia 2610028H24Rik5 RIKEN cDNA 2610028H24 gene   --   10 (38.84 cM) 76449081 
chicken
(Gallus gallus)
Aves C21orf586
chromosome 21 open reading frame 58
35(a)
1 ↔ 1
7(7150313-7158873) ENSGALG00000007487
lizard
(Anolis carolinensis)
Reptilia C21orf586
chromosome 21 open reading frame 58
37(a)
1 ↔ 1
GL343645.1(166454-185838)
African clawed frog
(Xenopus laevis)
Amphibia BX843330.12   -- 72.02(n)    BX843330.1 
zebrafish
(Danio rerio)
Actinopterygii C6H21orf586
chromosome 21 open reading frame 58
39(a)
1 ↔ 1
6(11280082-11307376) ENSDARG00000044549


ENSEMBL Gene Tree for C21orf58 (if available)
TreeFam Gene Tree for C21orf58 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for C21orf58 (see all 582)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 21 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs72787661,2
C,F--33103940(+) GGTGGC/TTGTCC 1 -- int110Minor allele frequency- T:0.17NA WA CSA 380
rs1388944611,2
--33104101(+) TATGTA/CTACTA 1 -- int10--------
rs731467091,2
C,F--33104213(+) TCCACA/GTGGTA 1 -- int12Minor allele frequency- G:0.13NA 122
rs28392081,2
C--33104400(+) TGTGTA/C/G/
        
TGACG
1 -- int13NA 18
rs1997254721,2
C--33104431(+) TATTTA/TATTTT 1 -- ut310--------
rs1892678121,2
--33104499(+) CACTGC/TAGCTT 1 -- ut310--------
rs1162095451,2
F--33104509(+) TCTAAC/TTCCTG 1 -- ut311Minor allele frequency- T:0.01WA 118
rs110890571,2
C--33104593(+) TTTTTT/AAAATT 1 -- ut314Minor allele frequency- A:0.10NA WA EA 360
rs81298831,2
C--33104615(+) gagacA/Ggggtc 1 -- ut31 ese30--------
rs1809515361,2
--33104642(+) GCTGGC/TCTCGA 1 -- ut310--------

HapMap Linkage Disequilibrium report for C21orf58 (47720095 - 47743789 bp)

Structural Variations
     Database of Genomic Variants (DGV) 8 variations for C21orf58:    About this table    
Variant IDTypeSubtypePubMed ID
nsv3547CNV Insertion18451855
nsv519904CNV Loss19592680
nsv914141CNV Loss21882294
nsv914135CNV Loss21882294
dgv4817n71CNV Loss21882294
nsv470910CNV Gain18288195
nsv914139CNV Gain21882294
nsv527355CNV Gain19592680

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing C21orf58
DNA2.0 Custom Variant and Variant Library Synthesis for C21orf58

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for C21orf58 gene integrated from 10 sources:
(articles sorted by number of sources associating them with C21orf58)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  2. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. (PubMed id 11707072)1, 2 Reymond A....Antonarakis S.E. (Genomics 2001)
  3. The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 2 Hattori M.... Yaspo M.-L. (Nature 2000)
  4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  5. Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways. (PubMed id 18624398)1 Wang J....He F. (J. Proteome Res. 2008)
  6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  8. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)
  9. [IMAGE: molecular integration of the analysis of the human genome and its expression]. (PubMed id 7757816)1 Auffray C....Lamy B. (C. R. Acad. Sci. III, Sci. Vie 1995)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54058 HGNC: 1300 AceView: C21orf58 Ensembl:ENSG00000160298 euGenes: HUgn54058
ECgene: C21orf58 H-InvDB: C21orf58

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for C21orf58 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for C21orf58 gene:
Search GeneIP for patents involving C21orf58

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for C21orf58  
 Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for C21orf58  
 OriGene qSTAR qPCR primer pairs in human, mouse for C21orf58   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for C21orf58   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for C21orf58   OriGene Custom Protein Services for C21orf58  

 
 
 Block miRNA regulation of human, mouse, rat C21orf58 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing C21orf58
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C21orf58 Predesigned siRNA for gene silencing in human, mouse, rat C21orf58
 QuantiFast Probe-based Assays in human, mouse, rat C21orf58 QuantiTect SYBR Green Assays in human, mouse, rat C21orf58
 Custom PCR Arrays for C21orf58 Search Chromatin IP Primers for C21orf58
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat C21orf58  Search GeneGlobe Interaction Network for C21orf58
 Regulatory tfbs in C21orf58 promoter
 GenScript Custom Purified and Recombinant Proteins Services for C21orf58 GenScript cDNA clones with any tag delivered in your preferred vector for C21orf58
 GenScript Custom Assay Services for C21orf58 GenScript Custom overexpressing Cell Line Services for C21orf58
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
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 Search Tocris compounds for C21orf58 (CU058)
 Browse Sino Biological Proteins
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 Protein Production Services
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 C21orf58 antibodies
 Antibodies for C21orf58
 See all of Abcam's Antibodies, Kits and Proteins for C21orf58
 Custom Antibody / Protein Production Service
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 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for C21orf58
 Antibodies for C21orf58
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 Browse ESI BIO Cell Lines and PureStem Progenitors for C21orf58
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf58
 SwitchGear 3'UTR luciferase reporter plasmids for C21orf58
 Browse SwitchGear Promoter luciferase reporter plasmids for C21orf58
 Search ThermoFisher Antibodies for C21orf58
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C21orf58
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C21orf58
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for C21orf58
 LSBio Antibodies in human, mouse, rat for C21orf58
Customized transgenic rodents for:
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 Browse compounds at ApexBio
 Search Addgene for plasmids for C21orf58
  Search eBioscience for proteins for C21orf58
  Search eBioscience for elisas for C21orf58
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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