Advanced Search (alpha)

""
 
Search By
Section
for


Category   Symbol Source: HGNC EntrezGene Ensembl
GIFtS

Search by expression pattern



C21orf49 Gene

RNA gene   GIFtS: 29

GC21P034144
chromosome 21 open reading frame 49
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
"" "" "" "" "" "" "" "" "" "" "" "" "" "" "" ""Services    
"" "" "" "" "" "" "" "" "" "" "" "" ""
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase, and/or 9Nature:405,311-319 and CroW21)
About This Section

  User Feedback
Aliases & Descriptions
chromosome 21 open reading frame 491 2
spliced EST T190199

External Ids:    HGNC: 12901   Entrez Gene: 540672   Ensembl: ENSG000002059307   UniProtKB: Q17RA53   

Search outside databases for aliases for C21orf49 gene

Previous GC identifers: GC21U990060 GC21P033066

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  User Feedback
  --
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences, Whole Chromsome Sequence According to Nature (Cited Here with Permission):405,311-319 and CroW21)
About This Section

  User Feedback
Regulatory elements:
"" SABiosciences Regulatory transcription factor binding sites in the C21orf49 gene upstream (promoter) region "":
GATA-1   p53   FOXO3b   FOXO3a   C/EBPalpha   GR-beta   GR-alpha   RFX1   MIF-1   FOXO4   

Epigenetics:
"" Search SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for C21orf49 ""

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.11   Ensembl cytogenetic band:  21q22.11   HGNC cytogenetic band: 21q22.11
Nature(405: 311-319) cytogenetic band:   21q22.11
C21orf49 Gene in genomic location: bands according to Ensembl, locations according to "" (and/or Entrez Gene and/or Ensembl if different)
""
GeneLoc gene densities for chromosome 21         GeneLoc Exon Structure

(about GC identifiers)
GC21P034144:   GeneLoc Nature:405,311-319
Start:
34,144,411 bp from pter       19,721,142 bp from centromere
End:
34,266,043 bp from pter 19,737,649 bp from centromere
Size:
121,633 bases 16,508 bases
Orientation:
plus strand plus strand
RefSeq DNA sequence:
NC_000021.8  NT_011512.11  

genomic clones: pS12

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

  User Feedback
UniProtKB/Swiss-Prot: CU049_HUMAN, Q17RA5 (See protein sequence)
Recommended Name: Putative uncharacterized protein C21orf49  
Size: 79 amino acids; 8913 Da



ENSEMBL proteins: 
ENSP00000410562 ENSP00000417758 ENSP00000371815 ENSP00000408057 ENSP00000371812 


Human Recombinant Proteins 
""Browse Purified and Recombinant Proteins at Millipore
""Browse Human Recombinant Proteins at Sigma-Aldrich
"" Browse R&D Systems for human recombinant proteins
""Browse recombinant and purified proteins available from Enzo Life Sciences
""Browse Abnova for HuPro® and/or Recombinant Proteins
""Browse Origene full length recombinant human proteins expressed in human HEK293 cells
""Browse Sino Biological Recombinant Proteins  ""


Antibodies for C21orf49: 
""Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
""Browse Antibodies at Sigma-Aldrich
"" Browse R&D Systems for Antibodies
""Browse Abnova for Monoclonal and Polyclonal Antibodies
""Browse Origene Antibodies ""
""Browse antibodies at Epitomics

Assays for C21orf49: 
""Browse Kits and Assays available from Millipore
""Browse ELISAs at Sigma-Aldrich
"" Browse R&D Systems for biochemical assays
""Browse Enzo Life Sciences for kits & assays

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

  User Feedback

ProtoNet protein and cluster: Q17RA5

(According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
About This Section

  User Feedback
Inhib.
RNA:
""Browse for Gene Knock-down Tools from Millipore
""Browse Abnova for Chimera RNAi Products
"" Origene 29mer shRNA kits in GFP-retroviral vector (see all 2): C21orf49
Origene shRNA RFP (see all 2): C21orf49
Origene basic RS shRNA (see all 2): C21orf49

""Applied Biosystems Silencer® siRNAs for C21orf49
""Sigma-Aldrich siRNA for C21orf49
Sigma-Aldrich shRNA for C21orf49
Explore Sigma-Aldrich super-pooled esiRNAs
Clones:""Browse Clones for the Expression of Recombinant Proteins Available from Millipore
""Browse iPSC Reprogramming Factors at Sigma-Aldrich
""Browse Origene untagged/tagged cDNA clones in CMV expression vector
""Browse Sino Biological Human cDNA Clones  ""
(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
About This Section

  User Feedback
"" Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C21orf49
(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

  User Feedback
"" Browse drugs & compounds from Enzo Life Sciences
""Browse Small Molecules at Sigma-Aldrich

"" Browse Tocris compounds for C21orf49

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
Expression Assays from Applied Biosystems)
About This Section

  User Feedback
Inhib.
RNA:
""Browse for Gene Knock-down Tools from Millipore
""Browse Abnova for Chimera RNAi Products
"" Origene 29mer shRNA kits in GFP-retroviral vector (see all 2): C21orf49
Origene shRNA RFP (see all 2): C21orf49
Origene basic RS shRNA (see all 2): C21orf49

""Sigma-Aldrich siRNA for C21orf49
Sigma-Aldrich shRNA for C21orf49
Explore Sigma-Aldrich super-pooled esiRNAs

microRNA:""Search SABiosciences for microRNAs that regulate C21orf49: ""

Clones:"" clones: 
Primers:"" Origene genome-wide validated SYBR primer pairs: C21orf49
""SABiosciences RT2 qPCR Primer Assay for C21orf49: PPH57901A ""

Additional cDNA sequence: 

AK096601.1 BC034794.1 BC117397.1 BC117399.1 

3 DOTS entries:

DT.442944  DT.205334  DT.95302313 

"" highest scoring ESTs for C21orf49:

AA779903 AK096601 AV655412 BX477211 T95301 AA361369 AI214627 AV717800 AW263082 BC034794 

Unigene Cluster for C21orf49:

Chromosome 21 open reading frame 49
Hs.54725  [show with all ESTs]
Unigene Representative Sequence: AK096601


GeneLoc Exon Structure

7 Ensembl transcripts including schematic representations:
ENST00000454365  ENST00000477513  ENST00000382378  ENST00000453404  ENST00000382377  ENST00000491756  
ENST00000382375  
(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
About This Section

  User Feedback

C21orf49 expression in normal and diseased human tissues

"" Applied Biosystems TaqMan ® Gene Expression Assays for C21orf49

1""  / 2""  / 3""

5 probe-sets matching C21orf49 gene

Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
90342_at2, 3 U95-D 1 0.88 1.00 0.80 0.70 AA779903 0.60 1.00 0.82 1
76427_i_at2, 3 U95-D 1 0.61 1.00 0.62 1.08 T95301 0.60 1.00 0.82 1
76429_r_at2, 3 U95-D 1 0.56 1.00 0.51 1.26 T95301 0.60 1.00 0.82 1
1557782_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
1559755_at2 U133Plus2 1 0.46 1.00 -- -- -- -- -- -- --
About this table

"" C21orf49 for expression           About GeneDecksing

Data from Genenote  (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.54725
Primers:"" Origene genome-wide validated SYBR primer pairs: C21orf49 ""
""SABiosciences RT2 qPCR Primer Assay for C21orf49: PPH57901A ""
(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

  User Feedback
ENSEMBL Gene Tree for C21orf49
(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

  User Feedback
  --
(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
About This Section

  User Feedback
  --
(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

  User Feedback
  --

(Possibly Related Articles in Doctor's Guide)
About This Section

  User Feedback
  --

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

  User Feedback
6 PubMed articles for C21orf49 gene:
(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

  User Feedback
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)
(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

  User Feedback
Entrez Gene: 54067 HGNC: 1290 Ensembl:ENSG00000205930 euGenes: HUgn54067 ECgene: C21orf49
H-InvDB: C21orf49
(According to HUGE)
About This Section

  User Feedback
  --
(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

  User Feedback
  --
(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section

  User Feedback
Patent Information for C21orf49 gene: ""
Search GeneIP for patents involving C21orf49

GeneCards and IP: ""
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search


(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Novus Biologicals,
Epitomics, Sigma-Aldrich, R&D Systems, SABiosciences, Millipore, Abnova,
Clones available from OriGene, Sigma-Aldrich, Sino Biological, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

  User Feedback
""
""
Products for C21orf49:
"" TaqMan ® Gene Expression Assays
"" TaqMan ® Genotyping Assays
 "" Free SNP selection tool

""
"" Millipore Custom Antibody & Bulk Services
"" Millipore Preclinical / Clinical Development Services
"" Millipore Immunoassay Services
"" Millipore Target Screening & Profiling Services

""
"" Predesigned and custom siRNAs for C21orf49"" Browse antibodies at Sigma-Aldrich
"" Explore super-pooled esiRNAs"" Browse proteins at Sigma-Aldrich
"" Lentivirus-delivered shRNAs for C21orf49"" Browse small molecules at Sigma-Aldrich
"" "Your Favorite Gene" Pathways"" Browse ELISAs at Sigma-Aldrich
"" Browse iPSC Reprogramming Factors at Sigma-Aldrichfeedback


 ""  ""
"" Antibodies  "" Primer Pairs  
"" Cell Culture Products  "" ELISAs  
"" Flow Cytometry Kits  "" Protease Activity Assays & Reagents  
"" Cell Selection/Detection Kits & Reagents  "" ELISA/Assay Development Kits & Reagents  
"" Multiplex/Array Assay Kits & Reagents  "" ELISpot Kits & Development Modules  
"" Recombinant & Natural Proteins  

"" Search for Recombinant Proteins
"" Search for Antibodies
"" Search for Chimera RNAi
"" Custom Service for Mouse Mab
"" Custom Service for Rabbit Pab from Full-length Protein


""""""""
"" Search for Antibodies & Assays

"" Tagged/untagged cDNA clones
"" Validated SYBR primer pairs
"" Purified proteins from HEK293T cells
"" Western blot validated antibodies
"" shRNA in GFP-retroviral vector
"" Custom immunoassay development
"" Search Tocris compounds for C21orf49
"" Regulatory tfbs in C21orf49 upstream (promoter) region
"" Search Chromatin IP Primers for C21orf49
"" Search DNA Methylation qPCR Primer Assays for C21orf49
"" RT2 qPCR Primer Assay for C21orf49
"" Search GNC Networks for C21orf49
"" Search for microRNAs that regulate C21orf49
""""""""
"" Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
"" Novus Biologicals
"" Novus Tissue Slides
"" Browse antibodies at Epitomics
"" Browse Sino Biological Proteins and Antibodies
"" Browse Sino Biological cDNA Clones
"" Antibodies/Proteins Production Services
"" Rabbit Monoclonal Antibody Platform
"" Bulk Purchasing
  User Feedback        

GeneCards Homepage - Last full update: 21 May 2010 - Incremental updates: 24 May 2010 , 20 Jun 2010

View Random Gene

Category
acyl-CoA synthetase family member 3
GIFtS Group
The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

C21orf49 gene at Home site.
hostname: server4.xennexinc.com db build: 72 index build: 72d solr: 1.4