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C21orf2 Gene

protein-coding   GIFtS: 50
GCID: GC21M045749

Chromosome 21 Open Reading Frame 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, 15RNAdb, and/or 11Nature:405,311-319 and CroW21)
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Aliases
Chromosome 21 Open Reading Frame 21 2     Nuclear Encoded Mitochondrial Protein, CDNA A2-YF511
Leucine Rich Repeat Containing 761 2     LRRC762
YF5/A22 3     Nuclear Encoded Mitochondrial Protein C21orf22
Nuclear Encoded Mitochondrial Protein1     C21orf-HUMF09G8.53

External Ids:    HGNC: 12601   Entrez Gene: 7552   Ensembl: ENSG000001602267   OMIM: 6031915   UniProtKB: O438223   

Export aliases for C21orf2 gene to outside databases

Previous GC identifers: GC21M042258 GC21M042341 GC21M044605 GC21M044573 GC21M031119


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for C21orf2 Gene:
Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear
gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of
them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome
(DS) brain, which may represent mitochondrial dysfunction in DS patients. (provided by RefSeq, Sep 2012)

GeneCards Summary for C21orf2 Gene:
C21orf2 (chromosome 21 open reading frame 2) is a protein-coding gene. Diseases associated with C21orf2 include labyrinthitis, and down syndrome.

UniProtKB/Swiss-Prot: CU002_HUMAN, O43822
Function: May play roles in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of
cell morphology and cytoskeletal organization




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics, Whole Chromsome Sequence According to Nature (Cited Here with Permission):405,311-319 and CroW21)
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RefSeq DNA sequence:
NC_000021.9  NT_011512.12  NC_018932.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the C21orf2 gene promoter:
         Spz1   AML1a   Pax-6   STAT5A   NF-kappaB   GATA-2   YY1   AREB6   NF-kappaB2   NF-kappaB1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

   Search Chromatin IP Primers for C21orf2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C21orf2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.3   Ensembl cytogenetic band:  21q22.3   HGNC cytogenetic band: 21q22.3
Nature(405: 311-319) cytogenetic band:   21q22.3
C21orf2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C21orf2 gene location
GeneLoc information about chromosome 21         GeneLoc Exon Structure

(about GC identifiers)
GC21M045749:   GeneLoc Nature:405,311-319
Start:
45,748,827 bp from pter       31,258,219 bp from centromere
End:
45,759,285 bp from pter 31,268,538 bp from centromere
Size:
10,459 bases 10,320 bases
Orientation:
minus strand minus strand

Whole chromosome sequencing:
cDNA sequence: Y11392
genomic clones: Q5B10


(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CU002_HUMAN, O43822 (See protein sequence)
Recommended Name: Protein C21orf2  
Size: 256 amino acids; 28340 Da
Secondary accessions: A8MPS9 O14993 Q8N5X6 Q99837 Q99838
Alternative splicing: 4 isoforms:  O43822-1   O43822-2   O43822-3   O43822-4   (No experimental confirmation available. Contains a phosphoserine at position 177)

Explore the universe of human proteins at neXtProt for C21orf2: NX_O43822

Explore proteomics data for C21orf2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See C21orf2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001258369.1  NP_001258370.1  NP_001258371.1  NP_004919.1  

    ENSEMBL proteins: 
     ENSP00000344566   ENSP00000381047   ENSP00000317302  

    C21orf2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR001611 Leu-rich_rpt
     IPR025875 Leu-rich_rpt_4
     IPR003603 U2A'_phosphoprotein32A_C

    Graphical View of Domain Structure for InterPro Entry O43822

    ProtoNet protein and cluster: O43822

    2 Blocks protein domains:
    IPB001611 Leucine-rich repeat signature
    IPB003603 Leucine-rich-associated


    UniProtKB/Swiss-Prot: CU002_HUMAN, O43822
    Similarity: Contains 3 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRCT domain


    C21orf2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CU002_HUMAN, O43822
    Function: May play roles in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of
    cell morphology and cytoskeletal organization

         Genatlas biochemistry entry for C21orf2:
    chromosome 21 open reading frame 2,mitochondrial protein,25kDa,with two alternatively spliced transcripts,widely
    expressed,encoded by a nuclear gene in the DFNB8/DFNB10 region

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    C21orf2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C21orf2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for C21orf2
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    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    nucleus3
    cytosol2
    mitochondrion2
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IDA--

    C21orf2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for C21orf2
    Interactions:

        Search GeneGlobe Interaction Network for C21orf2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for C21orf2 (ENSP000003445664) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAEAENSP000003028304STRING: ENSP00000302830
    RMND5AENSP000002836324STRING: ENSP00000283632
    RMND5BENSP000003206234STRING: ENSP00000320623
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization IMP--
    GO:0008360regulation of cell shape IMP--
    GO:0030030cell projection organization ----
    GO:0060271cilium morphogenesis IEA--

    C21orf2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for C21orf2 (CU002)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for C21orf2 gene (4 alternative transcripts): 
    NM_001271440.1  NM_001271441.1  NM_001271442.1  NM_004928.2  

    Unigene Cluster for C21orf2:

    Chromosome 21 open reading frame 2
    Hs.517331  [show with all ESTs]
    Unigene Representative Sequence: AK074162
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000339818(uc002zeo.1 uc002zep.2 uc002zer.2 uc002zeq.2)
    ENST00000470196 ENST00000496321 ENST00000462742(uc002zes.1) ENST00000397956
    ENST00000325223 ENST00000478674
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat C21orf2
      QuantiFast Probe-based Assays in human, mouse, rat C21orf2

    Additional mRNA sequence: 

    AK074162.1 BC031300.1 BC072012.1 U84569.1 U84570.1 Y11392.1 Z93322.1 

    14 DOTS entries:

    DT.75199150  DT.100024554  DT.207415  DT.40307132  DT.95170249  DT.40132285  DT.433168  DT.75131362 
    DT.121140878  DT.87017391  DT.92425350  DT.121140886  DT.92425351  DT.95170250 

    Selected AceView cDNA sequences (see all 162):

    BM023369 AI391609 BM709571 CA314162 AI423069 Z93322 BF946507 AI282432 
    Y11392 BM761336 AA447767 BE856252 BQ189620 NM_004928 AI598246 AI870362 
    AA496497 BU733416 BM547786 BC031300 BC072012 AI301036 AI744074 CA489339 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for C21orf2 (see all 9)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c · 10d ^ 11 ^ 12
    SP1:                          -     -     -                                   -                                             
    SP2:                          -     -                                         -                                             
    SP3:                          -     -                                         -                                             
    SP4:                          -     -                                                                                       
    SP5:                                -                                                                                       


    ECgene alternative splicing isoforms for C21orf2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    C21orf2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCGCAGCCC
    C21orf2 Expression
    About this image


    C21orf2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Neural Tube (Nervous System)
             Telencephalon
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Lung (Respiratory System)
             Stem Bronchi
    C21orf2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    C21orf2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.517331
        Custom PCR Arrays for C21orf2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C21orf2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for C21orf2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia 1810043G02Rik1 , 5 RIKEN cDNA 1810043G02 gene1, 5 79.38(n)1
    75.5(a)1
      10 (39.72 cM)5
    678841  NM_026431.21  NP_080707.21 
     779785245 
    chicken
    (Gallus gallus)
    Aves C9H21ORF21 chromosome 9 open reading frame, human C21orf2 68.94(n)
    63.86(a)
      424866  NM_001006544.1  NP_001006544.1 
    lizard
    (Anolis carolinensis)
    Reptilia C21orf26
    chromosome 21 open reading frame 2
    50(a)
    1 ↔ 1
    3(33679053-33686607)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia c21orf21 chromosome 21 open reading frame 2 54.65(n)
    51.44(a)
      394810  NM_203871.1  NP_989202.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005373911 protein C21orf2-like 62.87(n)
    56.12(a)
      100537391  XM_003199532.2  XP_003199580.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG149956
    CG152086
    --
    24(a)
    23(a)
    many → 1
    many → 1
    3L(4094343-4103256)
    X(10794393-10795771)
    worm
    (Caenorhabditis elegans)
    Secernentea F09G8.56
    Protein F09G8.5 (F09G8.5) mRNA, complete cds
    19(a)
    1 ↔ 1
    III(8254975-8257619) WBGene00017320


    ENSEMBL Gene Tree for C21orf2 (if available)
    TreeFam Gene Tree for C21orf2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for C21orf2 (see all 406)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 21 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1866894361,2
    C--31118650(+) TCCCTC/GCTGGG 4 -- ds50010--------
    rs1402175731,2
    --31118679(+) GCCTGC/TGTCAG 4 -- ds50010--------
    rs568254651,2
    C,F--31118701(+) GCTGCG/ATGGAG 4 -- ds50012Minor allele frequency- A:0.14WA 120
    rs1464393481,2
    --31118809(+) CTGCTC/TGGCTT 4 -- ds50010--------
    rs1914926551,2
    --31118810(+) TGCTCA/GGCTTG 4 -- ds50010--------
    rs1181870371,2
    F--31118825(+) CCCATT/GTTTGG 4 -- ds50011Minor allele frequency- G:0.03EA 120
    rs1156086421,2
    C,F--31118840(+) ACTTGG/AGGAGG 4 -- ds50011Minor allele frequency- A:0.01WA 118
    rs733740091,2
    C,F--31118880(+) CTGGAC/TGTGCT 4 -- ds50011Minor allele frequency- T:0.50WA 2
    rs2019453531,2
    --31118888(+) GCTTC-/TGGCTG 4 -- ds50010--------
    rs1840460381,2
    --31118923(+) TGAGGA/TGGTGC 4 -- ds50010--------

    HapMap Linkage Disequilibrium report for C21orf2 (45748827 - 45759285 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for C21orf2 (see all 18):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2723642CNV Deletion23290073
    esv2723643CNV Deletion23290073
    esv2723638CNV Deletion23290073
    esv1476049CNV Deletion17803354
    esv1005686CNV Deletion20482838
    nsv509800CNV Insertion20534489
    dgv4769n71CNV Loss21882294
    dgv4773n71CNV Loss21882294
    dgv4772n71CNV Loss21882294
    dgv4770n71CNV Loss21882294

    Human Gene Mutation Database (HGMD): C21orf2
    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603191    OMIM disorders: --

    5 diseases for C21orf2:    
    About MalaCards
    labyrinthitis    down syndrome    friedreich ataxia    ataxia
    cerebritis

    1 disease from the University of Copenhagen DISEASES database for C21orf2:
    Friedreich ataxia

    C21orf2 for disorders           About GeneDecksing


    Export disorders for C21orf2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for C21orf2 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with C21orf2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a novel gene, C21orf2, on human chromosome 21q22.3 and its exclusion as the APECED gene by mutation analysis. (PubMed id 9465297)1, 2, 3 Scott H.S.... Antonarakis S.E. (Genomics 1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 2 Hattori M.... Yaspo M.-L. (Nature 2000)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. (PubMed id 21834987)2 Bai S.W.... Ridley A.J. (BMC Biol. 2011)
    7. Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)2 Oppermann F.S.... Daub H. (Mol. Cell. Proteomics 2009)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    9. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H.... Kim N.S. (Mamm. Genome 2005)
    10. Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: challenging the gene dosage effect hypothesis (Part III). (PubMed id 12624744)1 Cheon M.S....Lubec G. (Amino Acids 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 755 HGNC: 1260 AceView: C21orf2 Ensembl:ENSG00000160226 euGenes: HUgn755
    ECgene: C21orf2 H-InvDB: C21orf2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for C21orf2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for C21orf2 gene:
    Search GeneIP for patents involving C21orf2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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