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Aliases for C20orf96 Gene

Aliases for C20orf96 Gene

  • Chromosome 20 Open Reading Frame 96 2 3 5
  • Uncharacterized Protein C20orf96 3
  • DJ1103G7.2 3

External Ids for C20orf96 Gene

Previous GeneCards Identifiers for C20orf96 Gene

  • GC20U990108
  • GC20M000199

Summaries for C20orf96 Gene

GeneCards Summary for C20orf96 Gene

C20orf96 (Chromosome 20 Open Reading Frame 96) is a Protein Coding gene.

Additional gene information for C20orf96 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C20orf96 Gene

Genomics for C20orf96 Gene

Regulatory Elements for C20orf96 Gene

Enhancers for C20orf96 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20H000266 1.5 FANTOM5 ENCODE 13.1 +23.9 23854 1 HDGF PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 C20orf96 ZCCHC3 NRSN2-AS1 DEFB129 DEFB128 NRSN2 GC20P000265 ENSG00000272874
GH20H000323 1.4 ENCODE dbSUPER 12.9 -35.7 -35730 6 HDGF PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 TBC1D20 DEFB129 ACTG1P3 ENSG00000272874 DEFB126 DEFB125 ZCCHC3 C20orf96 NRSN2-AS1 NRSN2
GH20H000289 1 ENCODE 17.7 -0.2 -203 3 FOXA2 ATF1 ARNT ARID4B SIN3A BRCA1 YY1 ZNF766 ZNF207 ATF7 C20orf96 ZCCHC3
GH20H000330 1.4 Ensembl ENCODE dbSUPER 12.3 -40.1 -40071 1 ELF3 ARID4B KLF17 THRB RAD21 RFX5 ZNF143 ZNF207 MIXL1 THAP11 ZCCHC3 C20orf96 RBCK1 TRIB3 DEFB132 DEFB129 GC20P000328 GC20M000330
GH20H000278 0.7 Ensembl ENCODE 20.9 +11.9 11886 1 CTCF POLR2A C20orf96 ENSG00000272874
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C20orf96 on UCSC Golden Path with GeneCards custom track

Promoters for C20orf96 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000133394 378 1201 ATF1 ARNT ARID4B SIN3A BRCA1 YY1 ZNF766 ZNF207 ATF7 SP3

Genomic Location for C20orf96 Gene

Chromosome:
20
Start:
270,863 bp from pter
End:
290,778 bp from pter
Size:
19,916 bases
Orientation:
Minus strand

Genomic View for C20orf96 Gene

Genes around C20orf96 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C20orf96 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C20orf96 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C20orf96 Gene

Proteins for C20orf96 Gene

  • Protein details for C20orf96 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NUD7-CT096_HUMAN
    Recommended name:
    Uncharacterized protein C20orf96
    Protein Accession:
    Q9NUD7
    Secondary Accessions:
    • A3KPE0
    • B2RPH9
    • Q8N840
    • Q8NAX5

    Protein attributes for C20orf96 Gene

    Size:
    363 amino acids
    Molecular mass:
    42859 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC03772.1; Type=Frameshift; Positions=304; Evidence={ECO:0000305};

neXtProt entry for C20orf96 Gene

Post-translational modifications for C20orf96 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C20orf96 Gene

No data available for DME Specific Peptides for C20orf96 Gene

Domains & Families for C20orf96 Gene

Gene Families for C20orf96 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C20orf96 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C20orf96 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C20orf96: view

No data available for UniProtKB/Swiss-Prot for C20orf96 Gene

Function for C20orf96 Gene

Gene Ontology (GO) - Molecular Function for C20orf96 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016491 oxidoreductase activity IEA --
genes like me logo Genes that share ontologies with C20orf96: view
genes like me logo Genes that share phenotypes with C20orf96: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C20orf96 Gene

Localization for C20orf96 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C20orf96 gene
Compartment Confidence
nucleus 3
golgi apparatus 2
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
  • Nucleus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C20orf96 Gene

Pathways & Interactions for C20orf96 Gene

SuperPathways for C20orf96 Gene

No Data Available

Interacting Proteins for C20orf96 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000353470%0d%0a9606.ENSP00000314879%0d%0a9606.ENSP00000346627%0d%0a
Selected Interacting proteins: Q9NUD7-CT096_HUMAN ENSP00000353470 for C20orf96 Gene via IID STRING

Gene Ontology (GO) - Biological Process for C20orf96 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with C20orf96: view

No data available for Pathways by source and SIGNOR curated interactions for C20orf96 Gene

Drugs & Compounds for C20orf96 Gene

No Compound Related Data Available

Transcripts for C20orf96 Gene

Unigene Clusters for C20orf96 Gene

Chromosome 20 open reading frame 96:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C20orf96 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11
SP1: - - - -
SP2: - - - -
SP3: - - - - -
SP4: - - - - - - -
SP5: - - - - -
SP6: - -
SP7: - - - - - - - - -
SP8:
SP9: - - -
SP10: - -

Relevant External Links for C20orf96 Gene

GeneLoc Exon Structure for
C20orf96
ECgene alternative splicing isoforms for
C20orf96

Expression for C20orf96 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C20orf96 Gene

Protein differential expression in normal tissues from HIPED for C20orf96 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for C20orf96 Gene



Protein tissue co-expression partners for C20orf96 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C20orf96 Gene:

C20orf96

SOURCE GeneReport for Unigene cluster for C20orf96 Gene:

Hs.348112

Evidence on tissue expression from TISSUES for C20orf96 Gene

  • Nervous system(4.4)
  • Kidney(4.2)
genes like me logo Genes that share expression patterns with C20orf96: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C20orf96 Gene

Orthologs for C20orf96 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C20orf96 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C20H20orf96 33
  • 98.31 (n)
C20ORF96 34
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C24H20orf96 33
  • 80.33 (n)
C20orf96 34
  • 65 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C13H20orf96 33
  • 75.9 (n)
C20orf96 34
  • 59 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC502684 33
  • 71.34 (n)
mouse
(Mus musculus)
Mammalia 6820408C15Rik 33 16 34
  • 67.72 (n)
oppossum
(Monodelphis domestica)
Mammalia C20orf96 34
  • 46 (a)
OneToOne
chicken
(Gallus gallus)
Aves C20ORF96 33
  • 47.37 (n)
C20orf96 34
  • 26 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C20orf96 34
  • 30 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:dkey-76p14.2 33
  • 44.23 (n)
C11H20orf96 34
  • 24 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 18 (a)
OneToOne
Species where no ortholog for C20orf96 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C20orf96 Gene

ENSEMBL:
Gene Tree for C20orf96 (if available)
TreeFam:
Gene Tree for C20orf96 (if available)

Paralogs for C20orf96 Gene

(1) SIMAP similar genes for C20orf96 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with C20orf96: view

No data available for Paralogs for C20orf96 Gene

Variants for C20orf96 Gene

Sequence variations from dbSNP and Humsavar for C20orf96 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1000052997 -- 277,500(+) GGGCT(A/G)AGGTG intron-variant
rs1000058930 -- 280,039(+) TGGAG(G/T)AGAAG intron-variant
rs1000130577 -- 278,713(+) TCTGG(A/G)ACGGG intron-variant
rs1000257796 -- 272,079(+) CTATT(-/A)AAAAA intron-variant
rs1000326942 -- 280,229(+) TGTAC(C/T)TCCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C20orf96 Gene

Variant ID Type Subtype PubMed ID
dgv4219n100 CNV gain 25217958
dgv65n68 CNV loss 17160897
esv32859 CNV gain 17666407
esv33186 CNV loss 17666407
esv3352048 CNV duplication 20981092
esv3584398 CNV loss 25503493
esv3893263 CNV loss 25118596
nsv3248 CNV insertion 18451855
nsv469544 CNV loss 16826518
nsv952159 CNV deletion 24416366

Variation tolerance for C20orf96 Gene

Residual Variation Intolerance Score: 77.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.83; 17.47% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C20orf96 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C20orf96

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C20orf96 Gene

Disorders for C20orf96 Gene

Relevant External Links for C20orf96

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C20orf96

No disorders were found for C20orf96 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C20orf96 Gene

Publications for C20orf96 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 60
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3 60

Products for C20orf96 Gene

Sources for C20orf96 Gene

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