C20orf85 Gene
protein-coding GIFtS: 39
GCID: GC20P056726
|
|
chromosome 20 open reading frame 85
| |
Aliases
for C20orf85 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 20 Open Reading Frame 851 2 | | LLC11 2 | | BA196N14.11 | | Low In Lung Cancer 12 | | Uncharacterized Protein C20orf852 |
Export aliases for C20orf85 gene to outside databasesPrevious GC identifers: GC20P056454 GC20P057364 GC20P057411 GC20P056159 GC20P053508 |
Summaries
for C20orf85 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C20orf85 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C20orf85 gene promoter:
HOXA9 HOXA9B POU6F1 (c2) Meis-1b ARP-1 Meis-1a RSRFC4 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C20orf85
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C20orf85 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q13.32 Ensembl cytogenetic band: 20q13.32 HGNC cytogenetic band: 20q13.32C20orf85 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P056726: view genomic region
(about GC identifiers)
Start:
|
56,725,960 bp from pter |
End:
|
56,736,206 bp from pter |
Size:
|
10,247 bases |
Orientation:
|
plus strand |
|
Proteins
for C20orf85 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CT085_HUMAN, Q9H1P6 (See
protein sequence)Recommended Name: Uncharacterized protein C20orf85 Size: 137 amino acids; 15719 DaExplore the universe of human proteins at neXtProt for C20orf85: NX_Q9H1P6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H1P6
C20orf85 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_848551.1
ENSEMBL proteins: ENSP00000360210
Human Recombinant Protein Products:
C20orf85 Antibody Products:
Assay Products for C20orf85: |
Protein
Domains /
Families
for C20orf85 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C20orf85 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9H1P6ProtoNet protein and cluster: Q9H1P6 |
Function
for C20orf85 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf85 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf85
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C20orf85 (NM_178456) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C20orf85 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C20orf85 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C20orf85 |
|
Pathways & Interactions
for C20orf85 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C20orf85
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for C20orf85 (ENSP000003602104) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C20orf85 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C20orf85
Search CenterWatch for drugs/clinical trials and news about C20orf85 / CT085
|
Transcripts
for C20orf85 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C20orf85 gene: NM_178456.2 Unigene Cluster for C20orf85: Chromosome 20 open reading frame 85 Hs.43977 [show with all ESTs]Unigene Representative Sequence: NM_1784561 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000371168(uc002xyv.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf85 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf85
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C20orf85 (NM_178456) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C20orf85 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C20orf85 |
Additional cDNA sequence: BC035405.1 2 DOTS entries: DT.441044 DT.97767983 24/42 AceView cDNA sequences (see all 42): AI190771 BU681063 BC035405 AI583214 AA993460 AA707502 AW450920 AI147327 CB241220 AI811321 AI955404 AW590326 AA382612 AI017118 NM_178456 AI041237 AA398083 BU676204 AW517470 AA335282 BI831542 AA634507 AA382727 AA815369
GeneLoc Exon Structure
|
Expression
for C20orf85 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C20orf85 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGATGTTGCA
About this image
See C20orf85 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C20orf85
SOURCE GeneReport for Unigene cluster: Hs.43977
SABiosciences Custom PCR Arrays for C20orf85
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C20orf85
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C20orf85 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C20orf85 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C20orf85 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C20orf85 |
Orthologs
for C20orf85 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C20orf85 gene from 3/12 species (see all 12) About this table
ENSEMBL Gene Tree for C20orf85 (if available)
TreeFam Gene Tree for C20orf85 (if available) |
Paralogs
for C20orf85 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C20orf85 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C20orf85 (56725960 - 56736206 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C20orf85: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C20orf85 |
|
Disorders
/ Diseases
for C20orf85 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C20orf85 for disorders About GeneDecksing
1  disease for C20orf85: About MalaCardslung cancer
1 disease from the University of Copenhagen DISEASES database for C20orf85:Lung cancer Export disorders for C20orf85 gene to outside databases
|
Publications
for C20orf85 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C20orf85 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C20orf85) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Inactivation of LLC1 gene in nonsmall cell lung cancer. (PubMed id 17304513)1 Hong K.M....Jen J. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for C20orf85 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C20orf85 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C20orf85 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C20orf85 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C20orf85 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C20orf85 gene:
Search GeneIP for patents involving C20orf85
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C20orf85 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C20orf85 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C20orf85 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C20orf85 | | | OriGene Protein Over-expression Lysate for C20orf85 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C20orf85 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf85 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf85 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C20orf85 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C20orf85 | | OriGene Custom Protein Services for C20orf85 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C20orf85 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C20orf85 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C20orf85 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C20orf85 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C20orf85 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C20orf85 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | C20orf85 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C20orf85 |
|  |  |  | | | | Search ThermoFisher Antibodies for C20orf85 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C20orf85 |
|
|
|
|
