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Aliases for C20orf85 Gene

Aliases for C20orf85 Gene

  • Chromosome 20 Open Reading Frame 85 2 3 5
  • Low In Lung Cancer 1 2 3
  • BA196N14.1 3
  • LLC1 3

External Ids for C20orf85 Gene

Previous GeneCards Identifiers for C20orf85 Gene

  • GC20P056454
  • GC20P057364
  • GC20P057411
  • GC20P056159
  • GC20P056726
  • GC20P053508

Summaries for C20orf85 Gene

GeneCards Summary for C20orf85 Gene

C20orf85 (Chromosome 20 Open Reading Frame 85) is a Protein Coding gene. Diseases associated with C20orf85 include Lung Cancer.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C20orf85 Gene

Genomics for C20orf85 Gene

Regulatory Elements for C20orf85 Gene

Enhancers for C20orf85 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C20orf85 on UCSC Golden Path with GeneCards custom track

Genomic Location for C20orf85 Gene

58,150,904 bp from pter
58,161,150 bp from pter
10,247 bases
Plus strand

Genomic View for C20orf85 Gene

Genes around C20orf85 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C20orf85 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C20orf85 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C20orf85 Gene

Proteins for C20orf85 Gene

  • Protein details for C20orf85 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C20orf85
    Protein Accession:

    Protein attributes for C20orf85 Gene

    137 amino acids
    Molecular mass:
    15719 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C20orf85 Gene

Proteomics data for C20orf85 Gene at MOPED

Post-translational modifications for C20orf85 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C20orf85 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C20orf85 Gene

Domains & Families for C20orf85 Gene

Protein Domains for C20orf85 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C20orf85: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C20orf85 Gene

Function for C20orf85 Gene

genes like me logo Genes that share phenotypes with C20orf85: view

Animal Model Products

miRNA for C20orf85 Gene

miRTarBase miRNAs that target C20orf85

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C20orf85 Gene

Localization for C20orf85 Gene

Subcellular locations from

Jensen Localization Image for C20orf85 Gene COMPARTMENTS Subcellular localization image for C20orf85 gene
Compartment Confidence
cytosol 2
extracellular 2
mitochondrion 1
nucleus 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C20orf85 Gene

Pathways & Interactions for C20orf85 Gene

SuperPathways for C20orf85 Gene

No Data Available

Interacting Proteins for C20orf85 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000360210 for C20orf85 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for C20orf85 Gene


No data available for Pathways by source and SIGNOR curated interactions for C20orf85 Gene

Drugs & Compounds for C20orf85 Gene

No Compound Related Data Available

Transcripts for C20orf85 Gene

mRNA/cDNA for C20orf85 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(42) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C20orf85 Gene

Chromosome 20 open reading frame 85:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C20orf85 Gene

No ASD Table

Relevant External Links for C20orf85 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C20orf85 Gene

mRNA expression in normal human tissues for C20orf85 Gene

mRNA differential expression in normal tissues according to GTEx for C20orf85 Gene

This gene is overexpressed in Testis (x23.2), Fallopian Tube (x12.6), Cervix - Endocervix (x9.4), and Lung (x5.8).

SOURCE GeneReport for Unigene cluster for C20orf85 Gene Hs.43977

genes like me logo Genes that share expression patterns with C20orf85: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C20orf85 Gene

Orthologs for C20orf85 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C20orf85 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C13H20orf85 35
  • 85.48 (n)
  • 86.29 (a)
C13H20ORF85 36
  • 86 (a)
(Canis familiaris)
Mammalia C24H20orf85 35
  • 83.94 (n)
  • 83.21 (a)
C20orf85 36
  • 83 (a)
(Mus musculus)
Mammalia 1700021F07Rik 35
  • 75.74 (n)
  • 71.32 (a)
1700021F07Rik 16
1700021F07Rik 36
  • 71 (a)
(Pan troglodytes)
Mammalia C20H20orf85 35
  • 99.03 (n)
  • 98.54 (a)
C20orf85 36
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC689618 35
  • 75.8 (n)
  • 72.59 (a)
(Monodelphis domestica)
Mammalia C20orf85 36
  • 55 (a)
(Ornithorhynchus anatinus)
Mammalia C20orf85 36
  • 56 (a)
(Gallus gallus)
Aves C20H20ORF85 35
  • 60.61 (n)
  • 57.85 (a)
C20orf85 36
  • 38 (a)
(Anolis carolinensis)
Reptilia C20orf85 36
  • 60 (a)
Species with no ortholog for C20orf85:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C20orf85 Gene

Gene Tree for C20orf85 (if available)
Gene Tree for C20orf85 (if available)

Paralogs for C20orf85 Gene

No data available for Paralogs for C20orf85 Gene

Variants for C20orf85 Gene

Sequence variations from dbSNP and Humsavar for C20orf85 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs16984945 - 58,153,552(+) ATACC(A/G)TCTGA reference, missense
rs17440813 - 58,160,703(+) GCTTC(A/G)TCGGC reference, missense
rs45576936 - 58,153,576(+) AGCAC(A/G/T)GCAGA reference, missense
rs884341 -- 58,161,618(+) GCCTC(A/G)TGAAC downstream-variant-500B
rs1412980 -- 58,150,004(+) TCCTA(C/G)ATCGT upstream-variant-2KB

Variation tolerance for C20orf85 Gene

Residual Variation Intolerance Score: 92% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.67; 65.90% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for C20orf85 Gene

Disorders for C20orf85 Gene

MalaCards: The human disease database

(1) MalaCards diseases for C20orf85 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
lung cancer
  • lung cancer, protection against
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for C20orf85

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C20orf85: view

No data available for UniProtKB/Swiss-Prot and Genatlas for C20orf85 Gene

Publications for C20orf85 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  3. Inactivation of LLC1 gene in nonsmall cell lung cancer. (PMID: 17304513) Hong K.M. … Jen J. (Int. J. Cancer 2007) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3

Products for C20orf85 Gene

Sources for C20orf85 Gene