C20orf27 Gene
protein-coding GIFtS: 44
GCID: GC20M003734
|
|
chromosome 20 open reading frame 27
| |
Aliases
for C20orf27 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 20 Open Reading Frame 271 2 | | FLJ205501 | | UPF0687 Protein C20orf272 |
Export aliases for C20orf27 gene to outside databasesPrevious GC identifers: GC20M003722 GC20M003729 GC20M003682 |
Summaries
for C20orf27 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for C20orf27
|
Genomic Views
for C20orf27 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C20orf27 gene promoter:
GR Lmo2 CUTL1 Nkx2-5 GR-alpha NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C20orf27
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C20orf27 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p13 Ensembl cytogenetic band: 20p13 HGNC cytogenetic band: 20p13C20orf27 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M003734: view genomic region
(about GC identifiers)
Start:
|
3,734,155 bp from pter |
End:
|
3,749,034 bp from pter |
Size:
|
14,880 bases |
Orientation:
|
minus strand |
|
Proteins
for C20orf27 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CT027_HUMAN, Q9GZN8 (See
protein sequence)Recommended Name: UPF0687 protein C20orf27 Size: 174 amino acids; 19291 Da
Secondary accessions: A8K4J0 D3DVX8 Q5JX81 Q9NWX3Alternative splicing: 2 isoforms: Q9GZN8-1 Q9GZN8-2 Explore the universe of human proteins at neXtProt for C20orf27: NX_Q9GZN8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9GZN8
C20orf27 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001034229.1 NP_001245358.1 NP_001245359.1
ENSEMBL proteins: ENSP00000369097 ENSP00000217195 ENSP00000382591 ENSP00000382580
Human Recombinant Protein Products for C20orf27:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- |
C20orf27 for ontologies About GeneDecksing
C20orf27 Antibody Products:
Assay Products for C20orf27: |
Protein
Domains /
Families
for C20orf27 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C20orf27 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9GZN8ProtoNet protein and cluster: Q9GZN8 UniProtKB/Swiss-Prot: CT027_HUMAN, Q9GZN8Similarity: Belongs to the UPF0687 family |
Function
for C20orf27 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
C20orf27 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for C20orf27:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf27 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf27 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C20orf27 (NM_001039140) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C20orf27 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C20orf27 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C20orf27 |
|
Pathways & Interactions
for C20orf27 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C20orf27
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5 Interacting proteins for C20orf27 (Q9GZN83 ENSP000002171954) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
C20orf27 for ontologies About GeneDecksing
|
Drugs & Compounds
for C20orf27 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C20orf27
Search CenterWatch for drugs/clinical trials and news about C20orf27 / CT027
|
Transcripts
for C20orf27 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C20orf27 gene (4 alternative transcripts): NM_017874.2 NM_001039140.2 NM_001258429.1 NM_001258430.1 Unigene Cluster for C20orf27: Chromosome 20 open reading frame 27 Hs.274422 [show with all ESTs]Unigene Representative Sequence: AK0976455 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000379772(uc002wjf.1 uc002wjh.1 uc002wji.1) ENST00000217195
ENST00000487464 ENST00000399683 ENST00000399672
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf27 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf27 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C20orf27 (NM_001039140) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C20orf27 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C20orf27 |
Additional cDNA sequence: AK000557.1 AK024220.1 AK097645.1 AK225109.1 AK290955.1 BC010873.1 BC012196.1 BC024036.1 BC069204.1 NR_047675.1 11 DOTS entries: DT.213919 DT.100033070 DT.97814780 DT.100663342 DT.120800940 DT.95340448 DT.100663344 DT.100839117 DT.101985115 DT.120800897 DT.97797510 24/324 AceView cDNA sequences (see all 324): BQ678751 CR623724 CF127904 CR616702 BE779165 BU623536 BU856502 BQ680115 CR599225 T32118 BG397156 BE795641 AA719102 CD674785 AL519665 BQ441762 BU168654 BM821179 AA434441 CR597067 BF102631 BG468438 BU151594 CR592157
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for C20orf27 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c |
|---|
|
| SP1: | | | | | | | | | | | | | - | | - | | - | | | | | | | | - | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for C20orf27
|
Expression
for C20orf27 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C20orf27 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTAGGAGGG
About this image
See C20orf27 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C20orf27
SOURCE GeneReport for Unigene cluster: Hs.274422
SABiosciences Custom PCR Arrays for C20orf27
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C20orf27
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C20orf27 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C20orf27 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C20orf27 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C20orf27 |
Orthologs
for C20orf27 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C20orf27 gene from 5/13 species (see all 13) About this table
ENSEMBL Gene Tree for C20orf27 (if available)
TreeFam Gene Tree for C20orf27 (if available) |
Paralogs
for C20orf27 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C20orf27 gene
C20orf27 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for C20orf27
PGOHUM00000239446 PGOHUM00000248807
|
Genomic Variants
for C20orf27 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C20orf27 (3734155 - 3749034 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C20orf27: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C20orf27 |
|
Disorders
/ Diseases
for C20orf27 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 C20orf27 for disorders About MalaCards
C20orf27 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: C20orf27 (3 documents)
Export disorders for C20orf27 gene to outside databases
|
Publications
for C20orf27 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C20orf27 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with C20orf27) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2, 3 Deloukas P....Rogers J. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- The protein network surrounding the human telomere re peat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
|
External Searches for C20orf27 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C20orf27 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C20orf27 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C20orf27 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C20orf27 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C20orf27 gene:
Search GeneIP for patents involving C20orf27
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C20orf27 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C20orf27 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C20orf27 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C20orf27 | | | OriGene Protein Over-expression Lysate for C20orf27 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C20orf27 | | OriGene 3'-UTR Clone for C20orf27 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf27 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf27 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C20orf27 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C20orf27 | | OriGene Custom Protein Services for C20orf27 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C20orf27 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C20orf27 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C20orf27 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C20orf27 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C20orf27 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C20orf27 |
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 | | | C20orf27 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C20orf27 |
|  |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C20orf27 |
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