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Aliases for C20orf24 Gene

Aliases for C20orf24 Gene

  • Chromosome 20 Open Reading Frame 24 2 3 5
  • Rab5-Interacting Protein 3 4
  • RIP5 3 4
  • Uncharacterized Protein C20orf24 3
  • PNAS-11 3

External Ids for C20orf24 Gene

Previous GeneCards Identifiers for C20orf24 Gene

  • GC20P034962
  • GC20P035872
  • GC20P035919
  • GC20P034667
  • GC20P035234
  • GC20P031970

Summaries for C20orf24 Gene

GeneCards Summary for C20orf24 Gene

C20orf24 (Chromosome 20 Open Reading Frame 24) is a Protein Coding gene. An important paralog of this gene is TGIF2-C20orf24.

Additional gene information for C20orf24 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C20orf24 Gene

Genomics for C20orf24 Gene

Regulatory Elements for C20orf24 Gene

Enhancers for C20orf24 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20H036627 1.6 FANTOM5 Ensembl ENCODE dbSUPER 13.8 +23.5 23549 3.5 SOX13 ATF1 FOXA2 MAX CEBPG POLR2A SCRT2 NR2F6 ATF7 RUNX3 C20orf24 NDRG3 MYL9 SLA2 RBL1 HNRNPA3P2
GH20H036643 1.6 FANTOM5 Ensembl ENCODE dbSUPER 12.1 +40.2 40216 4.1 SOX13 DRAP1 ZNF792 ZFP64 ARID4B MAX CEBPG ZNF644 POLR2A RERE NDRG3 SLA2 C20orf24 RBL1 SAMHD1 TGIF2 HNRNPA3P2
GH20H036583 1.4 FANTOM5 ENCODE dbSUPER 12.4 -20.7 -20661 3.7 INSM2 KLF17 ZNF2 ZNF366 ZSCAN5C FOS ATF7 EGR2 ZNF362 USF2 C20orf24 MYL9 PIR36258 TGIF2-C20orf24
GH20H036491 1.3 Ensembl ENCODE dbSUPER 11 -112.9 -112904 3.3 CTCF ARID4B MAX RAD21 EED SCRT2 SMC3 ZNF143 ATF7 ETV6 MYL9 C20orf24 NDRG3 MROH8 GC20P036472 GC20P036530
GH20H036644 1.1 ENCODE dbSUPER 12.1 +37.3 37349 0.2 SOX13 DRAP1 TFAP4 FOXA2 SAP130 ARID4B CEBPG DMAP1 ZSCAN9 SLC30A9 C20orf24 SLA2 HNRNPA3P2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C20orf24 on UCSC Golden Path with GeneCards custom track

Promoters for C20orf24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Locations for C20orf24 Gene

Genomic Locations for C20orf24 Gene
6,824 bases
Plus strand

Genomic View for C20orf24 Gene

Genes around C20orf24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C20orf24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C20orf24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C20orf24 Gene

Proteins for C20orf24 Gene

  • Protein details for C20orf24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C20orf24
    Protein Accession:
    Secondary Accessions:
    • E1P5U0
    • O00605
    • Q5QPG6
    • Q5QPG7
    • Q9BT03
    • Q9BZU7
    • Q9UI05

    Protein attributes for C20orf24 Gene

    137 amino acids
    Molecular mass:
    15487 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C20orf24 Gene


neXtProt entry for C20orf24 Gene

Post-translational modifications for C20orf24 Gene

  • Ubiquitination at Lys27
  • Modification sites at PhosphoSitePlus

Other Protein References for C20orf24 Gene

No data available for DME Specific Peptides for C20orf24 Gene

Domains & Families for C20orf24 Gene

Gene Families for C20orf24 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for C20orf24 Gene


Suggested Antigen Peptide Sequences for C20orf24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C20orf24: view

No data available for UniProtKB/Swiss-Prot for C20orf24 Gene

Function for C20orf24 Gene

Gene Ontology (GO) - Molecular Function for C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with C20orf24: view
genes like me logo Genes that share phenotypes with C20orf24: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C20orf24 Gene

Localization for C20orf24 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C20orf24 gene
Compartment Confidence
plasma membrane 2
cytosol 2
extracellular 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C20orf24: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C20orf24 Gene

Pathways & Interactions for C20orf24 Gene

SuperPathways for C20orf24 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with C20orf24: view

No data available for Pathways by source and SIGNOR curated interactions for C20orf24 Gene

Drugs & Compounds for C20orf24 Gene

No Compound Related Data Available

Transcripts for C20orf24 Gene

Unigene Clusters for C20orf24 Gene

Chromosome 20 open reading frame 24:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C20orf24 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c · 5d
SP1: - - -
SP3: - -
SP4: - - - -
SP5: -

Relevant External Links for C20orf24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C20orf24 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C20orf24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C20orf24 Gene

This gene is overexpressed in Whole Blood (x6.0) and Esophagus - Mucosa (x4.1).

Protein differential expression in normal tissues from HIPED for C20orf24 Gene

This gene is overexpressed in Breast (36.6) and Bone (17.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C20orf24 Gene

NURSA nuclear receptor signaling pathways regulating expression of C20orf24 Gene:


SOURCE GeneReport for Unigene cluster for C20orf24 Gene:


Evidence on tissue expression from TISSUES for C20orf24 Gene

  • Nervous system(3.4)
  • Lung(3)
  • Intestine(2.5)
  • Skin(2.4)
genes like me logo Genes that share expression patterns with C20orf24: view

No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C20orf24 Gene

Orthologs for C20orf24 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for C20orf24 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TGIF2 33
  • 99.51 (n)
(Canis familiaris)
Mammalia C24H20orf24 33
  • 86.82 (n)
(Mus musculus)
Mammalia 1110008F13Rik 33 16
  • 86.3 (n)
(Rattus norvegicus)
Mammalia RGD1307752 33
  • 86.3 (n)
(Bos Taurus)
Mammalia C13H20orf24 33
  • 85.79 (n)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 36 (a)
(Gallus gallus)
Aves C20H20ORF24 33 34
  • 73.13 (n)
(Anolis carolinensis)
Reptilia -- 34
  • 44 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c20orf24 33
  • 67.2 (n)
Str.6359 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.7273 33
(Danio rerio)
Actinopterygii c20orf24 33
  • 65.07 (n)
C23H20orf24 34
  • 42 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12107 33 34
  • 56.21 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004838 33
  • 51.73 (n)
(Caenorhabditis elegans)
Secernentea F44E7.9 33 34
  • 49.83 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G29020 33
  • 46.9 (n)
(Oryza sativa)
Liliopsida Os05g0110600 33
  • 52.08 (n)
Species where no ortholog for C20orf24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C20orf24 Gene

Gene Tree for C20orf24 (if available)
Gene Tree for C20orf24 (if available)

Paralogs for C20orf24 Gene

Paralogs for C20orf24 Gene

genes like me logo Genes that share paralogs with C20orf24: view

Variants for C20orf24 Gene

Sequence variations from dbSNP and Humsavar for C20orf24 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1000014129 -- 36,609,297(+) GCAGT(A/G)GAACA intron-variant
rs1000139994 -- 36,604,693(+) GATTG(C/G)CTGAG intron-variant, upstream-variant-2KB
rs1001014514 -- 36,610,467(+) GAGGC(C/T)GAGGC intron-variant
rs1001032150 -- 36,605,725(+) GCACG(C/G/T)CGGCG intron-variant, upstream-variant-2KB
rs1001048874 -- 36,610,239(+) AGATC(A/G)CGCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C20orf24 Gene

Variant ID Type Subtype PubMed ID
nsv1057192 CNV loss 25217958
nsv833967 CNV loss 17160897

Variation tolerance for C20orf24 Gene

Residual Variation Intolerance Score: 55.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.15; 3.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C20orf24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C20orf24 Gene

Disorders for C20orf24 Gene

Relevant External Links for C20orf24

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C20orf24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C20orf24 Gene

Publications for C20orf24 Gene

  1. RIP5 is a RIP-homologous inducer of cell death. (PMID: 15178406) Zha J … Shu HB (Biochemical and biophysical research communications 2004) 2 3 60
  2. An unappreciated role for RNA surveillance. (PMID: 14759258) Hillman RT … Brenner SE (Genome biology 2004) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  4. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4 60
  5. The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic. (PMID: 8824393) Vitale G … Zerial M (Cold Spring Harbor symposia on quantitative biology 1995) 3 4 60

Products for C20orf24 Gene

Sources for C20orf24 Gene

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