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Aliases for C20orf24 Gene

Aliases for C20orf24 Gene

  • Chromosome 20 Open Reading Frame 24 2 3 5
  • Rab5-Interacting Protein 3 4
  • RIP5 3 4
  • Uncharacterized Protein C20orf24 3
  • PNAS-11 3

External Ids for C20orf24 Gene

Previous GeneCards Identifiers for C20orf24 Gene

  • GC20P034962
  • GC20P035872
  • GC20P035919
  • GC20P034667
  • GC20P035234
  • GC20P031970

Summaries for C20orf24 Gene

GeneCards Summary for C20orf24 Gene

C20orf24 (Chromosome 20 Open Reading Frame 24) is a Protein Coding gene. An important paralog of this gene is TGIF2-C20orf24.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C20orf24 Gene

Genomics for C20orf24 Gene

Regulatory Elements for C20orf24 Gene

Enhancers for C20orf24 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20G036627 1.6 FANTOM5 Ensembl ENCODE dbSUPER 13.8 +23.5 23549 3.5 SOX13 ATF1 FOXA2 MAX CEBPG ZBTB40 ZNF664 TCF12 ZFHX2 GATA2 C20orf24 NDRG3 MYL9 SLA2 RBL1 HNRNPA3P2
GH20G036643 1.7 FANTOM5 Ensembl ENCODE dbSUPER 12.1 +40.2 40216 4.1 PKNOX1 NFIB ZFP64 ARID4B ZNF362 CEBPB MIER2 TGIF2 NFIC SSRP1 NDRG3 SLA2 C20orf24 RBL1 SAMHD1 TGIF2 HNRNPA3P2
GH20G036583 1.5 FANTOM5 ENCODE dbSUPER 12.4 -20.7 -20661 3.7 ATF1 ZNF2 FOS ZNF592 ZSCAN16 GLIS1 KDM1A HNF4A WT1 SP7 C20orf24 MYL9 PIR36258 TGIF2-C20orf24
GH20G036491 1.5 Ensembl ENCODE dbSUPER 11 -112.9 -112904 3.3 HDGF ATF1 PKNOX1 ARNT ARID4B TCF12 ZNF766 GATA2 ELK1 ZNF143 MYL9 C20orf24 NDRG3 MROH8 GC20P036472 GC20P036530
GH20G036644 1.2 ENCODE dbSUPER 12.1 +37.3 37349 0.2 HDGF HDAC1 FOXA2 PKNOX1 ARID4B DMAP1 ZSCAN9 SLC30A9 GATA4 ZSCAN5C C20orf24 SLA2 HNRNPA3P2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C20orf24 on UCSC Golden Path with GeneCards custom track

Promoters for C20orf24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000136719 666 2001 MLX CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC

Genomic Location for C20orf24 Gene

Chromosome:
20
Start:
36,605,734 bp from pter
End:
36,612,557 bp from pter
Size:
6,824 bases
Orientation:
Plus strand

Genomic View for C20orf24 Gene

Genes around C20orf24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C20orf24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C20orf24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C20orf24 Gene

Proteins for C20orf24 Gene

  • Protein details for C20orf24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BUV8-CT024_HUMAN
    Recommended name:
    Uncharacterized protein C20orf24
    Protein Accession:
    Q9BUV8
    Secondary Accessions:
    • E1P5U0
    • O00605
    • Q5QPG6
    • Q5QPG7
    • Q9BT03
    • Q9BZU7
    • Q9UI05

    Protein attributes for C20orf24 Gene

    Size:
    137 amino acids
    Molecular mass:
    15487 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C20orf24 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C20orf24 Gene

Post-translational modifications for C20orf24 Gene

  • Ubiquitination at posLast=2727
  • Modification sites at PhosphoSitePlus

Other Protein References for C20orf24 Gene

No data available for DME Specific Peptides for C20orf24 Gene

Domains & Families for C20orf24 Gene

Protein Domains for C20orf24 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C20orf24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C20orf24: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C20orf24 Gene

Function for C20orf24 Gene

Gene Ontology (GO) - Molecular Function for C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with C20orf24: view
genes like me logo Genes that share phenotypes with C20orf24: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C20orf24 Gene

Localization for C20orf24 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C20orf24 gene
Compartment Confidence
plasma membrane 2
cytosol 2
extracellular 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with C20orf24: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C20orf24 Gene

Pathways & Interactions for C20orf24 Gene

SuperPathways for C20orf24 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with C20orf24: view

No data available for Pathways by source and SIGNOR curated interactions for C20orf24 Gene

Drugs & Compounds for C20orf24 Gene

No Compound Related Data Available

Transcripts for C20orf24 Gene

Unigene Clusters for C20orf24 Gene

Chromosome 20 open reading frame 24:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C20orf24 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c · 5d
SP1: - - -
SP2:
SP3: - -
SP4: - - - -
SP5: -

Relevant External Links for C20orf24 Gene

GeneLoc Exon Structure for
C20orf24
ECgene alternative splicing isoforms for
C20orf24

Expression for C20orf24 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C20orf24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C20orf24 Gene

This gene is overexpressed in Whole Blood (x6.0) and Esophagus - Mucosa (x4.1).

Protein differential expression in normal tissues from HIPED for C20orf24 Gene

This gene is overexpressed in Breast (36.6) and Bone (17.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C20orf24 Gene



NURSA nuclear receptor signaling pathways regulating expression of C20orf24 Gene:

C20orf24

SOURCE GeneReport for Unigene cluster for C20orf24 Gene:

Hs.584985

Evidence on tissue expression from TISSUES for C20orf24 Gene

  • Nervous system(3.4)
  • Lung(3)
  • Intestine(2.5)
  • Skin(2.4)
genes like me logo Genes that share expression patterns with C20orf24: view

Primer Products

No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C20orf24 Gene

Orthologs for C20orf24 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for C20orf24 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TGIF2 34
  • 99.51 (n)
dog
(Canis familiaris)
Mammalia C24H20orf24 34
  • 86.82 (n)
mouse
(Mus musculus)
Mammalia 1110008F13Rik 34 16
  • 86.3 (n)
rat
(Rattus norvegicus)
Mammalia RGD1307752 34
  • 86.3 (n)
cow
(Bos Taurus)
Mammalia C13H20orf24 34
  • 85.79 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 36 (a)
OneToMany
chicken
(Gallus gallus)
Aves C20H20ORF24 34 35
  • 73.13 (n)
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 44 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia c20orf24 34
  • 67.2 (n)
Str.6359 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.7273 34
zebrafish
(Danio rerio)
Actinopterygii c20orf24 34
  • 65.07 (n)
C23H20orf24 35
  • 42 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG12107 34 35
  • 56.21 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004838 34
  • 51.73 (n)
worm
(Caenorhabditis elegans)
Secernentea F44E7.9 34 35
  • 49.83 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G29020 34
  • 46.9 (n)
rice
(Oryza sativa)
Liliopsida Os05g0110600 34
  • 52.08 (n)
Species where no ortholog for C20orf24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for C20orf24 Gene

ENSEMBL:
Gene Tree for C20orf24 (if available)
TreeFam:
Gene Tree for C20orf24 (if available)

Paralogs for C20orf24 Gene

Paralogs for C20orf24 Gene

genes like me logo Genes that share paralogs with C20orf24: view

Variants for C20orf24 Gene

Sequence variations from dbSNP and Humsavar for C20orf24 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1000014129 -- 36,609,297(+) GCAGT(A/G)GAACA intron-variant
rs1000139994 -- 36,604,693(+) GATTG(C/G)CTGAG intron-variant, upstream-variant-2KB
rs1001014514 -- 36,610,467(+) GAGGC(C/T)GAGGC intron-variant
rs1001032150 -- 36,605,725(+) GCACG(C/G/T)CGGCG intron-variant, upstream-variant-2KB
rs1001048874 -- 36,610,239(+) AGATC(A/G)CGCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C20orf24 Gene

Variant ID Type Subtype PubMed ID
nsv1057192 CNV loss 25217958
nsv833967 CNV loss 17160897

Variation tolerance for C20orf24 Gene

Residual Variation Intolerance Score: 55.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.15; 3.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C20orf24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C20orf24

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C20orf24 Gene

Disorders for C20orf24 Gene

Relevant External Links for C20orf24

Human Genome Epidemiology (HuGE) Navigator
C20orf24
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C20orf24

No disorders were found for C20orf24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C20orf24 Gene

Publications for C20orf24 Gene

  1. RIP5 is a RIP-homologous inducer of cell death. (PMID: 15178406) Zha J. … Shu H.B. (Biochem. Biophys. Res. Commun. 2004) 2 3 64
  2. An unappreciated role for RNA surveillance. (PMID: 14759258) Hillman R.T. … Brenner S.E. (Genome Biol. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4 64
  5. The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic. (PMID: 8824393) Vitale G. … Zerial M. (Cold Spring Harb. Symp. Quant. Biol. 1995) 3 4 64

Products for C20orf24 Gene

Sources for C20orf24 Gene

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