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Aliases for C20orf197 Gene

Aliases for C20orf197 Gene

  • Chromosome 20 Open Reading Frame 197 2 3 5

External Ids for C20orf197 Gene

Previous GeneCards Identifiers for C20orf197 Gene

  • GC20P058065
  • GC20P058630
  • GC20P055418

Summaries for C20orf197 Gene

GeneCards Summary for C20orf197 Gene

C20orf197 (Chromosome 20 Open Reading Frame 197) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C20orf197 Gene

Genomics for C20orf197 Gene

Regulatory Elements for C20orf197 Gene

Enhancers for C20orf197 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20F060054 1.3 FANTOM5 ENCODE 19.3 +1.1 1065 4.8 INSM2 YBX1 FEZF1 RAD21 GLIS2 SCRT2 ZNF143 FOS ZNF263 ZNF654 C20orf197 PPP1R3D FAM217B SYCP2 ENSG00000276093
GH20F060008 1.1 FANTOM5 Ensembl ENCODE 14.7 -47.4 -47425 1.0 MAX MYC C20orf197 PPP1R3D CDH26
GH20F060077 1.2 Ensembl ENCODE 11.9 +22.6 22576 1.8 HDGF PKNOX1 ATF1 SIN3A RAD21 ZNF335 GLIS2 SCRT2 ZNF207 RCOR1 C20orf197 PPP1R3D ENSG00000276093
GH20F060040 0.9 Ensembl ENCODE 14.7 -14.3 -14263 2.0 GTF2F1 ZNF687 MAX ZNF407 ZNF592 ZNF7 SREBF1 ARID3A MLLT1 FOSL2 C20orf197 CDH26
GH20F060045 1.4 FANTOM5 Ensembl ENCODE 9.3 -9.3 -9325 1.6 HDGF CTCF SIX4 OVOL3 MAX MNT ZNF592 OSR2 ZNF316 MTA1 C20orf197 PPP1R3D FAM217B PHACTR3 CDH26
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C20orf197 on UCSC Golden Path with GeneCards custom track

Promoters for C20orf197 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000403834 175 601 CTCF POLR2A MAX MYC

Genomic Location for C20orf197 Gene

60,055,925 bp from pter
60,072,953 bp from pter
17,029 bases
Plus strand

Genomic View for C20orf197 Gene

Genes around C20orf197 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C20orf197 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C20orf197 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C20orf197 Gene

Proteins for C20orf197 Gene

  • Protein details for C20orf197 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C20orf197
    Protein Accession:
    Secondary Accessions:
    • Q08EQ0

    Protein attributes for C20orf197 Gene

    126 amino acids
    Molecular mass:
    14459 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C20orf197 Gene


neXtProt entry for C20orf197 Gene

Post-translational modifications for C20orf197 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C20orf197 Gene

Domains & Families for C20orf197 Gene

Protein Domains for C20orf197 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C20orf197: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C20orf197 Gene

Function for C20orf197 Gene

Phenotypes for C20orf197 Gene

GenomeRNAi human phenotypes for C20orf197:
genes like me logo Genes that share phenotypes with C20orf197: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C20orf197 Gene

Localization for C20orf197 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C20orf197 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C20orf197 Gene

Pathways & Interactions for C20orf197 Gene

SuperPathways for C20orf197 Gene

No Data Available

Interacting Proteins for C20orf197 Gene

Selected Interacting proteins: Q8N268-CT197_HUMAN for C20orf197 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for C20orf197 Gene


No data available for Pathways by source and SIGNOR curated interactions for C20orf197 Gene

Transcripts for C20orf197 Gene

mRNA/cDNA for C20orf197 Gene

(8) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(15) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C20orf197 Gene

Chromosome 20 open reading frame 197:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C20orf197 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6
SP1: -
SP2: - -
SP3: - -

Relevant External Links for C20orf197 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C20orf197 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C20orf197 Gene

mRNA differential expression in normal tissues according to GTEx for C20orf197 Gene

This gene is overexpressed in Whole Blood (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of C20orf197 Gene:


SOURCE GeneReport for Unigene cluster for C20orf197 Gene:

genes like me logo Genes that share expression patterns with C20orf197: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C20orf197 Gene

Orthologs for C20orf197 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C20orf197 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C20H20orf197 34
  • 99.47 (n)
C20orf197 35
  • 99 (a)
Species where no ortholog for C20orf197 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C20orf197 Gene

Gene Tree for C20orf197 (if available)
Gene Tree for C20orf197 (if available)

Paralogs for C20orf197 Gene

No data available for Paralogs for C20orf197 Gene

Variants for C20orf197 Gene

Sequence variations from dbSNP and Humsavar for C20orf197 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1054636 -- 60,046,250(+) TTGCA(G/T)GAGGA upstream-variant-2KB
rs10718155 -- 60,054,654(+) TAACT(-/C)CCCCT intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs11086692 -- 60,047,940(+) GTCTC(-/T)TCCCC intron-variant
rs111356839 -- 60,046,504(+) AGAAG(A/T)AGCTC upstream-variant-2KB
rs111407472 -- 60,055,309(+) ACAAG(A/G)GCAGC intron-variant, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for C20orf197 Gene

Variant ID Type Subtype PubMed ID
esv2559283 CNV deletion 19546169
esv2631555 CNV insertion 19546169
esv3305313 CNV mobile element insertion 20981092
esv3440988 CNV insertion 20981092
nsv819951 CNV gain 19587683

Variation tolerance for C20orf197 Gene

Residual Variation Intolerance Score: 54.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.28; 6.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C20orf197 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C20orf197 Gene

Disorders for C20orf197 Gene

Relevant External Links for C20orf197

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C20orf197 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C20orf197 Gene

Publications for C20orf197 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 64
  4. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4 64
  5. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel D.P. … Karasik D. (BMC Med. Genet. 2007) 46 64

Products for C20orf197 Gene

Sources for C20orf197 Gene

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