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Aliases for C20orf196 Gene

Aliases for C20orf196 Gene

  • Chromosome 20 Open Reading Frame 196 2 3 5

External Ids for C20orf196 Gene

Previous GeneCards Identifiers for C20orf196 Gene

  • GC20P005680

Summaries for C20orf196 Gene

GeneCards Summary for C20orf196 Gene

C20orf196 (Chromosome 20 Open Reading Frame 196) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C20orf196 Gene

Genomics for C20orf196 Gene

Regulatory Elements for C20orf196 Gene

Enhancers for C20orf196 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20F005723 0.2 ENCODE 13.1 -27.2 -27166 0.2 IKZF1 TCF7 RARA C20orf196 LOC105372514
GH20F005724 0.9 Ensembl 13.1 -25.5 -25535 1.6 ATF1 MLX ARID4B DMAP1 ZNF48 SLC30A9 SP5 NFYC PPARG KAT8 C20orf196 LOC105372514
GH20F005745 0.6 ENCODE 9.8 -3.1 -3095 3.7 HINFP DDX20 PTRF RELA TEAD3 NR2F6 FOS ZNF740 HLF NR2F1 C20orf196 LOC105372514
GH20F005749 0.4 ENCODE 9.7 +0.9 889 2.9 HDGF PKNOX1 WRNIP1 ARID4B SIN3A ETS1 YY1 SLC30A9 ELK1 SP3 C20orf196 GC20P005890
GH20F005861 1.3 Ensembl ENCODE 5.6 +113.8 113780 4.9 PKNOX1 ZNF133 SIN3A FEZF1 ZNF2 GLIS2 CBX5 FOS ZNF263 SP3 CHGB RNU1-55P MCM8 TRMT6 C20orf196 GC20P005890
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C20orf196 on UCSC Golden Path with GeneCards custom track

Promoters for C20orf196 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000397109 365 1401 HDGF PKNOX1 WRNIP1 SIN3A ARID4B ETS1 YY1 SLC30A9 ELK1 SP3

Genomic Location for C20orf196 Gene

Chromosome:
20
Start:
5,750,335 bp from pter
End:
5,864,407 bp from pter
Size:
114,073 bases
Orientation:
Plus strand

Genomic View for C20orf196 Gene

Genes around C20orf196 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C20orf196 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C20orf196 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C20orf196 Gene

Proteins for C20orf196 Gene

  • Protein details for C20orf196 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IYI0-CT196_HUMAN
    Recommended name:
    Uncharacterized protein C20orf196
    Protein Accession:
    Q8IYI0
    Secondary Accessions:
    • A8K9J3
    • Q5TGA9
    • Q96LU1

    Protein attributes for C20orf196 Gene

    Size:
    205 amino acids
    Molecular mass:
    22938 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C20orf196 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C20orf196 Gene

Post-translational modifications for C20orf196 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C20orf196 Gene

Domains & Families for C20orf196 Gene

Protein Domains for C20orf196 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C20orf196: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C20orf196 Gene

Function for C20orf196 Gene

Phenotypes for C20orf196 Gene

genes like me logo Genes that share phenotypes with C20orf196: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C20orf196 Gene

Localization for C20orf196 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C20orf196 Gene COMPARTMENTS Subcellular localization image for C20orf196 gene
Compartment Confidence
cytosol 2
endoplasmic reticulum 2
golgi apparatus 2
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C20orf196 Gene

Pathways & Interactions for C20orf196 Gene

SuperPathways for C20orf196 Gene

No Data Available

Interacting Proteins for C20orf196 Gene

Selected Interacting proteins: Q8IYI0-CT196_HUMAN for C20orf196 Gene via MINT IID

Gene Ontology (GO) - Biological Process for C20orf196 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C20orf196 Gene

Transcripts for C20orf196 Gene

Unigene Clusters for C20orf196 Gene

Chromosome 20 open reading frame 196:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C20orf196 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c
SP1: - - - - -
SP2: - - - - - -
SP3: - -
SP4: - - - - -
SP5: -
SP6:

Relevant External Links for C20orf196 Gene

GeneLoc Exon Structure for
C20orf196
ECgene alternative splicing isoforms for
C20orf196

Expression for C20orf196 Gene

mRNA expression in normal human tissues for C20orf196 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C20orf196 Gene



NURSA nuclear receptor signaling pathways regulating expression of C20orf196 Gene:

C20orf196

SOURCE GeneReport for Unigene cluster for C20orf196 Gene:

Hs.529340
genes like me logo Genes that share expression patterns with C20orf196: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C20orf196 Gene

Orthologs for C20orf196 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C20orf196 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C20H20orf196 34
  • 97.72 (n)
C20orf196 35
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C13H20orf196 34
  • 83.33 (n)
C20orf196 35
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C24H20orf196 34
  • 83.09 (n)
C20orf196 35
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC681292 34
  • 78.91 (n)
mouse
(Mus musculus)
Mammalia 1110034G24Rik 34 16 35
  • 75 (n)
oppossum
(Monodelphis domestica)
Mammalia C20orf196 35
  • 52 (a)
OneToOne
chicken
(Gallus gallus)
Aves C3H20orf196 34
  • 50.17 (n)
Species where no ortholog for C20orf196 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C20orf196 Gene

ENSEMBL:
Gene Tree for C20orf196 (if available)
TreeFam:
Gene Tree for C20orf196 (if available)

Paralogs for C20orf196 Gene

Pseudogenes.org Pseudogenes for C20orf196 Gene

genes like me logo Genes that share paralogs with C20orf196: view

No data available for Paralogs for C20orf196 Gene

Variants for C20orf196 Gene

Sequence variations from dbSNP and Humsavar for C20orf196 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1008493 -- 5,789,907(+) gacag(A/G)ttatc intron-variant
rs10211706 -- 5,850,748(+) ctcgc(A/G)atctt intron-variant
rs10211801 -- 5,851,018(+) GGACA(A/G)TACAG intron-variant
rs1027707 -- 5,840,149(-) AAGCA(G/T)GCAAG intron-variant
rs1039845 -- 5,761,395(-) acatg(C/T)gcaga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C20orf196 Gene

Variant ID Type Subtype PubMed ID
dgv4242n100 CNV gain 25217958
dgv7449n54 CNV gain 21841781
dgv777e199 CNV deletion 23128226
esv27527 CNV loss 19812545
esv3368495 CNV insertion 20981092
esv34186 CNV loss 18971310
esv3645108 CNV loss 21293372
esv3645109 CNV gain 21293372
esv3645111 CNV loss 21293372
esv3893277 CNV gain 25118596
nsv1059145 CNV loss 25217958
nsv3270 CNV insertion 18451855
nsv3271 CNV insertion 18451855
nsv470539 CNV gain 18288195
nsv481615 CNV novel sequence insertion 20440878
nsv523886 CNV loss 19592680
nsv585331 CNV loss 21841781
nsv585332 CNV loss 21841781
nsv833905 CNV gain 17160897

Variation tolerance for C20orf196 Gene

Residual Variation Intolerance Score: 63.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.45; 43.08% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C20orf196 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C20orf196

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C20orf196 Gene

Disorders for C20orf196 Gene

Relevant External Links for C20orf196

Genetic Association Database (GAD)
C20orf196
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C20orf196

No disorders were found for C20orf196 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C20orf196 Gene

Publications for C20orf196 Gene

  1. Whole genome association scan for genetic polymorphisms influencing information processing speed. (PMID: 21130836) Luciano M. … Deary I.J. (Biol Psychol 2011) 3 46 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  3. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3 64
  4. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PMID: 20360068) Hutchins J.R. … Peters J.M. (Science 2010) 3 64
  5. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3 64

Products for C20orf196 Gene

Sources for C20orf196 Gene

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