Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C20orf173 Gene

Aliases for C20orf173 Gene

  • Chromosome 20 Open Reading Frame 173 2 3 5
  • Uncharacterized Protein C20orf173 3
  • DJ477O4.4 3

External Ids for C20orf173 Gene

Previous GeneCards Identifiers for C20orf173 Gene

  • GC20M033873
  • GC20M033833
  • GC20M034783
  • GC20M034830
  • GC20M033578
  • GC20M034109
  • GC20M030886

Summaries for C20orf173 Gene

GeneCards Summary for C20orf173 Gene

C20orf173 (Chromosome 20 Open Reading Frame 173) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C20orf173 Gene

Genomics for C20orf173 Gene

Regulatory Elements for C20orf173 Gene

Enhancers for C20orf173 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20F035615 0.2 ENCODE 16.3 -88.2 -88176 5.0 CREB3L1 MLX ZFP64 YBX1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 CPNE1 RBM12 NCOA6 RPL36P4 AAR2 C20orf173 RPF2P1 HMGB3P2 ENSG00000242507 PROCR
GH20F035765 1 FANTOM5 ENCODE 16.2 -239.9 -239894 9.2 HDGF PKNOX1 ARNT MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 CPNE1 RBM12 NCOA6 PHF20 AAR2 TRPC4AP PROCR RPF2P1 C20orf173 HMGB3P2
GH20F035756 0.4 ENCODE 16.2 -228.2 -228151 1.6 ELF3 PKNOX1 ZNF792 KLF17 ZNF384 CEBPG ZIC2 ZSCAN9 ZFHX2 CTBP1 CPNE1 RPF2P1 C20orf173 HMGB3P2 ENSG00000242507 CNBD2 MMP24-AS1 ENSG00000283527
GH20F035165 0.6 Ensembl ENCODE 16.2 +363.2 363160 1.4 HDAC1 TAL1 ETV1 JUN ZMYM3 ZNF175 MAX RAD21 CCNT2 RBAK EDEM2 C20orf173 RPF2P1 HMGB3P2 MMP24-AS1 ENSG00000242507 PROCR CNBD2
GH20F036091 0.7 FANTOM5 ENCODE 16.2 -563.4 -563437 3.6 SIN3A ZNF2 YY1 REST SMARCB1 KAT8 MEF2D SMARCA4 GLIS1 KDM1A EPB41L1 HMGB3P2 RPF2P1 C20orf173 ENSG00000242507 RPL36P4 CNBD2 CPNE1 DLGAP4 ENSG00000237063
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C20orf173 on UCSC Golden Path with GeneCards custom track

Genomic Location for C20orf173 Gene

Chromosome:
20
Start:
35,520,741 bp from pter
End:
35,529,652 bp from pter
Size:
8,912 bases
Orientation:
Minus strand

Genomic View for C20orf173 Gene

Genes around C20orf173 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C20orf173 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C20orf173 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C20orf173 Gene

Proteins for C20orf173 Gene

  • Protein details for C20orf173 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96LM9-CT173_HUMAN
    Recommended name:
    Uncharacterized protein C20orf173
    Protein Accession:
    Q96LM9
    Secondary Accessions:
    • A6PVJ1
    • Q2M293
    • Q5JWS4
    • Q9H449

    Protein attributes for C20orf173 Gene

    Size:
    149 amino acids
    Molecular mass:
    16552 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C20orf173 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C20orf173 Gene

Post-translational modifications for C20orf173 Gene

No Post-translational modifications

Other Protein References for C20orf173 Gene

No data available for DME Specific Peptides for C20orf173 Gene

Domains & Families for C20orf173 Gene

Protein Domains for C20orf173 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C20orf173: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C20orf173 Gene

Function for C20orf173 Gene

Gene Ontology (GO) - Molecular Function for C20orf173 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IBA --
genes like me logo Genes that share ontologies with C20orf173: view
genes like me logo Genes that share phenotypes with C20orf173: view

Animal Model Products

miRNA for C20orf173 Gene

miRTarBase miRNAs that target C20orf173

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C20orf173 Gene

Localization for C20orf173 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C20orf173 Gene COMPARTMENTS Subcellular localization image for C20orf173 gene
Compartment Confidence
extracellular 3
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C20orf173 Gene

Pathways & Interactions for C20orf173 Gene

SuperPathways for C20orf173 Gene

No Data Available

Interacting Proteins for C20orf173 Gene

Gene Ontology (GO) - Biological Process for C20orf173 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001574 ganglioside biosynthetic process IBA --
GO:0009311 oligosaccharide metabolic process IBA --
GO:0018279 protein N-linked glycosylation via asparagine IBA --
GO:0097503 sialylation IEA --
genes like me logo Genes that share ontologies with C20orf173: view

No data available for Pathways by source and SIGNOR curated interactions for C20orf173 Gene

Transcripts for C20orf173 Gene

mRNA/cDNA for C20orf173 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C20orf173 Gene

Chromosome 20 open reading frame 173:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C20orf173 Gene

No ASD Table

Relevant External Links for C20orf173 Gene

GeneLoc Exon Structure for
C20orf173
ECgene alternative splicing isoforms for
C20orf173

Expression for C20orf173 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C20orf173 Gene

mRNA differential expression in normal tissues according to GTEx for C20orf173 Gene

This gene is overexpressed in Testis (x52.1).

NURSA nuclear receptor signaling pathways regulating expression of C20orf173 Gene:

C20orf173

SOURCE GeneReport for Unigene cluster for C20orf173 Gene:

Hs.158680
genes like me logo Genes that share expression patterns with C20orf173: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C20orf173 Gene

Orthologs for C20orf173 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C20orf173 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC745624 34
  • 98.51 (n)
C20orf173 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC610148 34
  • 76.47 (n)
mouse
(Mus musculus)
Mammalia 6430550D23Rik 34 16 35
  • 67.49 (n)
rat
(Rattus norvegicus)
Mammalia LOC102550306 34
  • 66.28 (n)
cow
(Bos Taurus)
Mammalia C20orf173 35
  • 30 (a)
OneToOne
Species where no ortholog for C20orf173 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C20orf173 Gene

ENSEMBL:
Gene Tree for C20orf173 (if available)
TreeFam:
Gene Tree for C20orf173 (if available)

Paralogs for C20orf173 Gene

No data available for Paralogs for C20orf173 Gene

Variants for C20orf173 Gene

Sequence variations from dbSNP and Humsavar for C20orf173 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs111556808 -- 35,521,609(+) ACAGA(-/T/TT)TTTTT intron-variant
rs11167267 -- 35,521,445(+) GCAAG(G/T)TGTGA intron-variant, nc-transcript-variant
rs112208686 -- 35,520,284(+) AAAAA(A/T)TTTTT downstream-variant-500B
rs112216746 -- 35,522,965(+) ACCTG(A/G)GGTTG intron-variant
rs114285433 -- 35,527,594(+) ACAGG(A/G)GGCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C20orf173 Gene

Variant ID Type Subtype PubMed ID
nsv1062839 CNV loss 25217958
nsv3364 CNV insertion 18451855

Variation tolerance for C20orf173 Gene

Gene Damage Index Score: 4.13; 61.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C20orf173 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C20orf173

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C20orf173 Gene

Disorders for C20orf173 Gene

Relevant External Links for C20orf173

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C20orf173

No disorders were found for C20orf173 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C20orf173 Gene

Publications for C20orf173 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C20orf173 Gene

Sources for C20orf173 Gene

Content
Loading form....