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C20orf166-AS1 Gene

RNA gene   GIFtS: 30
GCID: GC20M061142

C20orf166 Antisense RNA 1

(Previous names: chromosome 20 open reading frame 200, non-protein coding...)
(Previous symbols: C20orf200, NCRNA00335)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Subcategory (RNA class): antisense

Quality score for this RNA gene is 3

Aliases
C20orf166 Antisense RNA 11 2 3     Chromosome 20 Open Reading Frame 2001
C20orf2001 2 3     Non-Protein Coding RNA 3351
NCRNA003351 2 3     C20orf166 Antisense Gene Protein 13
C20orf166 Antisense RNA 1 (Non-Protein Coding)1     

External Ids:    HGNC: 263931   Entrez Gene: 2538682   Ensembl: ENSG000001744037   UniProtKB: Q96NR23   

Export aliases for C20orf166-AS1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for C20orf166-AS1 Gene:
C20orf166-AS1 (C20orf166 antisense RNA 1) is an RNA gene, and is affiliated with the antisense RNA class. Diseases associated with C20orf166-AS1 include prostate cancer, and prostatitis.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000020.11  NC_018931.2  NT_011362.11  
Regulatory elements:
   Search for regulatory transcription factor binding sites for C20orf166-AS1
         Other transcription factors

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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C20orf166-AS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.33   Ensembl cytogenetic band:  20q13.33   HGNC cytogenetic band: 20q13.33

C20orf166-AS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C20orf166-AS1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M061142:  view genomic region     (about GC identifiers)

Start:
61,141,438 bp from pter      End:
61,148,768 bp from pter
Size:
7,331 bases      Orientation:
minus strand

1 alternative location:
Chr20-,NW_003571063 86,588-95,079     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: C2AS1_HUMAN, Q96NR2 (See protein sequence)
Recommended Name: Putative uncharacterized protein C20orf166-AS1  
Size: 134 amino acids; 14382 Da
Secondary accessions: Q52LN1

Explore the universe of human proteins at neXtProt for C20orf166-AS1: NX_Q96NR2

Explore proteomics data for C20orf166-AS1 at MOPED


See C20orf166-AS1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB


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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
LNCRNA: Long non-coding RNAs

ProtoNet protein and cluster: Q96NR2


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Animal Models:
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for C20orf166-AS1
Interactions:

    Search GeneGlobe Interaction Network for C20orf166-AS1

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for C20orf166-AS1 (C2AS1)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for C20orf166-AS1 gene: 
NM_152757.1  

Unigene Cluster for C20orf166-AS1:

C20orf166 antisense RNA 1
Hs.337024  [show with all ESTs]
Unigene Representative Sequence: NR_033263
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000412495(antisense) ENST00000475015(antisense) ENST00000436101(antisense)
miRNA
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Additional mRNA sequence: 

AK054875.1 AK056546.1 AL832097.1 BC093856.1 BC111938.1 NR_033263.1 

6 DOTS entries:

DT.95362483  DT.95362481  DT.120796467  DT.120796464  DT.97803718  DT.120796473 

14 AceView cDNA sequences:

NM_152757 AK054875 BM697184 BP373035 AK056546 BF307563 BI756373 BF811320 
BM668121 BF813244 AI266739 AL832097 BF817466 N87909 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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Expression evidence for C20orf166-AS1:none

C20orf166-AS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
C20orf166-AS1 Expression
About this image

C20orf166-AS1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

C20orf166-AS1 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.337024
    Custom PCR Arrays for C20orf166-AS1
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In Situ
Assay Products:
 

 
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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ENSEMBL Gene Tree for C20orf166-AS1 (if available)
TreeFam Gene Tree for C20orf166-AS1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for C20orf166-AS1 (see all 46)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 20 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs60622401,2
C,F,H--61142288(-) CACCCC/TTGACC 1 -- int15Minor allele frequency- T:0.08NS NA 850
rs1436548451,2
C--61142426(+) ACCTAC/TACAGC 1 -- spd10--------
rs1138874151,2
F--61143097(+) CCCTGC/TCCGGG 1 -- nc-transcript-variant2Minor allele frequency- T:0.50CSA 4
rs60622821,2
H--61143202(-) GATGAG/Aggcag 1 -- nc-transcript-variant4Minor allele frequency- A:0.00NS EA 418
rs1428506091,2
C--61143308(+) TGCTGA/GTGCAG 1 -- nc-transcript-variant0--------
rs2018059461,2
C--61143412(+) GCAGCC/TGGGGC 1 -- nc-transcript-variant1Minor allele frequency- T:0.00EU 979
rs2000199161,2
C--61143415(+) GCCGGG/AGCCTG 1 -- nc-transcript-variant1Minor allele frequency- A:0.00EU 1025
rs61220161,2
C,H--61143508(-) TCCTCC/TTGCAC 1 -- nc-transcript-varianttrp35Minor allele frequency- T:0.00NS EA NA 420
rs2020605531,2
C--61143777(+) CCTGCG/ATCCGC 1 -- nc-transcript-variant1Minor allele frequency- A:0.00EU 1319
rs1116515691,2
F--61143819(+) CGTGCG/ACGAGG 1 -- nc-transcript-variant2Minor allele frequency- A:0.50CSA 4

HapMap Linkage Disequilibrium report for C20orf166-AS1 (61141438 - 61148768 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for C20orf166-AS1 (see all 11):    About this table    
Variant IDTypeSubtypePubMed ID
esv2422398CNV Duplication17116639
nsv913073CNV Loss21882294
nsv913047CNV Loss21882294
dgv4610n71CNV Loss21882294
nsv470556CNV Loss18288195
dgv4603n71CNV Loss21882294
nsv913101CNV Loss21882294
dgv4608n71CNV Loss21882294
nsv459065CNV Gain19166990
nsv459068CNV Gain19166990

Site Specific Mutation Identification with PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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2 diseases for C20orf166-AS1:    
About MalaCards
prostate cancer    prostatitis


C20orf166-AS1 for disorders           About GeneDecksing


Export disorders for C20orf166-AS1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for C20orf166-AS1 gene integrated from 10 sources:
(articles sorted by number of sources associating them with C20orf166-AS1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  2. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (Nat. Genet. 2013)
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)2 Deloukas P....Rogers J. (Nature 2001)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 253868 HGNC: 26393 AceView: FLJ30313 Ensembl:ENSG00000174403 euGenes: HUgn253868
ECgene: C20orf166-AS1 H-InvDB: C20orf166-AS1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for C20orf166-AS1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for C20orf166-AS1 gene:
Search GeneIP for patents involving C20orf166-AS1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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