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Aliases for C20orf141 Gene

Aliases for C20orf141 Gene

  • Chromosome 20 Open Reading Frame 141 2 3 5
  • DJ860F19.4 3

External Ids for C20orf141 Gene

Previous GeneCards Identifiers for C20orf141 Gene

  • GC20P002783
  • GC20P002743
  • GC20P002790
  • GC20P002803
  • GC20P002749
  • GC20P002808

Summaries for C20orf141 Gene

GeneCards Summary for C20orf141 Gene

C20orf141 (Chromosome 20 Open Reading Frame 141) is a Protein Coding gene. An important paralog of this gene is ENSG00000241690.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C20orf141 Gene

Genomics for C20orf141 Gene

Regulatory Elements for C20orf141 Gene

Genomic Location for C20orf141 Gene

Chromosome:
20
Start:
2,814,987 bp from pter
End:
2,815,833 bp from pter
Size:
847 bases
Orientation:
Plus strand

Genomic View for C20orf141 Gene

Genes around C20orf141 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C20orf141 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C20orf141 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C20orf141 Gene

Proteins for C20orf141 Gene

  • Protein details for C20orf141 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NUB4-CT141_HUMAN
    Recommended name:
    Uncharacterized protein C20orf141
    Protein Accession:
    Q9NUB4

    Protein attributes for C20orf141 Gene

    Size:
    165 amino acids
    Molecular mass:
    17394 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C20orf141 Gene

Proteomics data for C20orf141 Gene at MOPED

Post-translational modifications for C20orf141 Gene

No Post-translational modifications

Other Protein References for C20orf141 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C20orf141 Gene

Domains & Families for C20orf141 Gene

Protein Domains for C20orf141 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for C20orf141 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C20orf141: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C20orf141 Gene

Function for C20orf141 Gene

genes like me logo Genes that share phenotypes with C20orf141: view

Animal Model Products

CRISPR Products

miRNA for C20orf141 Gene

miRTarBase miRNAs that target C20orf141

miRNA Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C20orf141 Gene

Localization for C20orf141 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C20orf141 Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C20orf141 Gene

Pathways & Interactions for C20orf141 Gene

SuperPathways for C20orf141 Gene

No Data Available

Interacting Proteins for C20orf141 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000369963%0d%0a9606.ENSP00000403397%0d%0a
Selected Interacting proteins: ENSP00000369963 for C20orf141 Gene via STRING

Symbol External ID(s) Details
ZDHHC17

Gene Ontology (GO) - Biological Process for C20orf141 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C20orf141 Gene

Drugs & Compounds for C20orf141 Gene

No Compound Related Data Available

Transcripts for C20orf141 Gene

mRNA/cDNA for C20orf141 Gene

Unigene Clusters for C20orf141 Gene

Chromosome 20 open reading frame 141:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C20orf141 Gene

No ASD Table

Relevant External Links for C20orf141 Gene

GeneLoc Exon Structure for
C20orf141
ECgene alternative splicing isoforms for
C20orf141

Expression for C20orf141 Gene

mRNA expression in normal human tissues for C20orf141 Gene

mRNA differential expression in normal tissues according to GTEx for C20orf141 Gene

This gene is overexpressed in Testis (x51.1).

Protein differential expression in normal tissues from HIPED for C20orf141 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C20orf141 Gene



SOURCE GeneReport for Unigene cluster for C20orf141 Gene Hs.352187

genes like me logo Genes that share expression patterns with C20orf141: view

Protein tissue co-expression partners for C20orf141 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C20orf141 Gene

Orthologs for C20orf141 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C20orf141 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C13H20orf141 35
  • 80.66 (n)
  • 75.31 (a)
C20orf141 36
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C24H20orf141 35
  • 82.21 (n)
  • 72.39 (a)
C20orf141 36
  • 70 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700020A23Rik 35
  • 75.66 (n)
  • 65.08 (a)
1700020A23Rik 16
1700020A23Rik 36
  • 63 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C20H20orf141 35
  • 98.59 (n)
  • 98.18 (a)
C20orf141 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100365450 35
  • 75.66 (n)
  • 66.67 (a)
Species with no ortholog for C20orf141:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C20orf141 Gene

ENSEMBL:
Gene Tree for C20orf141 (if available)
TreeFam:
Gene Tree for C20orf141 (if available)

Paralogs for C20orf141 Gene

Paralogs for C20orf141 Gene

(1) SIMAP similar genes for C20orf141 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with C20orf141: view

Variants for C20orf141 Gene

Sequence variations from dbSNP and Humsavar for C20orf141 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs6037418 -- 2,813,575(+) atggc(C/T)taata upstream-variant-2KB
rs7265164 -- 2,813,119(+) agaaa(A/G)gtttt upstream-variant-2KB
rs115199817 -- 2,813,564(+) GCAAC(A/G)CAAGA upstream-variant-2KB
rs117455978 -- 2,813,712(+) CATAG(C/T)AAATC upstream-variant-2KB
rs138286147 -- 2,813,603(+) AGTGC(C/T)TGGCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C20orf141 Gene

Variant ID Type Subtype PubMed ID
nsv833895 CNV Loss 17160897
nsv522009 CNV Gain 19592680
nsv510780 CNV Loss 20534489
nsv518364 CNV Loss 19592680

Variation tolerance for C20orf141 Gene

Residual Variation Intolerance Score: 61.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.89; 18.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C20orf141 Gene

HapMap Linkage Disequilibrium report
C20orf141

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C20orf141 Gene

Disorders for C20orf141 Gene

Relevant External Links for C20orf141

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C20orf141

No disorders were found for C20orf141 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C20orf141 Gene

Publications for C20orf141 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. (PMID: 24705354) Butland S.L. … Hayden M.R. (Hum. Mol. Genet. 2014) 3
  3. White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder. (PMID: 23218918) Sprooten E. … McIntosh A.M. (Psychiatry Res 2013) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3

Products for C20orf141 Gene

Sources for C20orf141 Gene

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