C20orf112 Gene
protein-coding GIFtS: 41
GCID: GC20M031030
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chromosome 20 open reading frame 112(Previous name: chromosome 20 open reading frame 113 )
(Previous symbol: C20orf113)
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Aliases
for C20orf112 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 20 Open Reading Frame 1121 2 | | DKFZP566G14241 | | C20orf1131 2 3 | | Chromosome 20 Open Reading Frame 1131 | | DJ1184F4.21 | | Uncharacterized Protein C20orf1122 | | DJ1184F4.41 | | |
Export aliases for C20orf112 gene to outside databasesPrevious GC identifers: GC20M030822 GC20M031732 GC20M031779 GC20M030498 GC20M027820 |
Summaries
for C20orf112 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C20orf112 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C20orf112 gene promoter:
COUP-TF1 AP-1 COUP HNF-4alpha2 XBP-1 E47 HNF-4alpha1 AREB6 COUP-TF Hand1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C20orf112
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C20orf112 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q11.21 Ensembl cytogenetic band: 20q11.21 HGNC cytogenetic band: 20q11.21C20orf112 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M031030: view genomic region
(about GC identifiers)
Start:
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31,030,862 bp from pter |
End:
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31,172,876 bp from pter |
Size:
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142,015 bases |
Orientation:
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minus strand |
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Proteins
for C20orf112 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CT112_HUMAN, Q96MY1 (See
protein sequence)Recommended Name: Uncharacterized protein C20orf112 Size: 436 amino acids; 47215 Da
Secondary accessions: Q5JYB7 Q6P0Y4 Q9BR34 Q9NQF6Alternative splicing: 2 isoforms: Q96MY1-1 Q96MY1-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for C20orf112: NX_Q96MY1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96MY1
C20orf112 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001243727.1 NP_542183.2
ENSEMBL proteins: ENSP00000352704 ENSP00000317413 ENSP00000364829 ENSP00000364830 ENSP00000201961 ENSP00000410774
Human Recombinant Protein Products for C20orf112:
C20orf112 Antibody Products:
Assay Products for C20orf112: |
Protein
Domains /
Families
for C20orf112 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C20orf112 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96MY1ProtoNet protein and cluster: Q96MY1 |
Function
for C20orf112 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf112 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf112
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C20orf112 (NM_080616) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C20orf112 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C20orf112 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C20orf112 |
|
Pathways & Interactions
for C20orf112 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C20orf112
|
Drugs & Compounds
for C20orf112 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C20orf112
Search CenterWatch for drugs/clinical trials and news about C20orf112 / CT112
|
Transcripts
for C20orf112 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C20orf112 gene (2 alternative transcripts): NM_001256798.1 NM_080616.4 Unigene Clusters for C20orf112: Chromosome 20 open reading frame 112 Hs.516978 [show with all ESTs], Hs.729596 [show with all ESTs]Unigene Representative Sequences: NM_001256798, AK0978049 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000359676(uc002wxu.4) ENST00000475781 ENST00000326071(uc002wxv.4)
ENST00000375677 ENST00000375678(uc002wxw.1) ENST00000201961 ENST00000419612
ENST00000470428 ENST00000485364(uc002wxx.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf112 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf112
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C20orf112 (NM_080616) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C20orf112 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C20orf112 |
Additional cDNA sequence: AK097804.1 BC023657.2 BC065483.1 16 DOTS entries: DT.416873 DT.40126477 DT.92418160 DT.92417470 DT.70100026 DT.97815864 DT.120819153 DT.97835999 DT.100757456 DT.100831868 DT.95369885 DT.97767532 DT.40218085 DT.95306451 DT.40109178 DT.70102846 24/215 AceView cDNA sequences (see all 215): AI978580 BC023657 BC065483 BI038949 AL122043 BX480855 AA948134 M86070 AA541249 BP361671 N33252 AI969732 BU070459 AI675993 BX090210 AL834520 AA563605 NM_080616 CR621375 AI762191 BM311140 AA331452 AI859356 AI610320
GeneLoc Exon Structure
|
Expression
for C20orf112 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C20orf112 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTATTACTTG
About this image
See C20orf112 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C20orf112
SOURCE GeneReport for Unigene clusters: Hs.516978 Hs.729596
SABiosciences Custom PCR Arrays for C20orf112
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C20orf112
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C20orf112 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C20orf112 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C20orf112 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C20orf112 |
Orthologs
for C20orf112 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C20orf112 gene from 5/12 species (see all 12) About this table
ENSEMBL Gene Tree for C20orf112 (if available)
TreeFam Gene Tree for C20orf112 (if available) |
Paralogs
for C20orf112 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C20orf112 gene
- NOL42
3 SIMAP similar genes for C20orf112 using alignment to 6 protein entries: CT112_HUMAN (see all proteins):RUNX1/C20orf112 fusion C20orf112/RUNX1 fusion NOL4
C20orf112 for paralogs About GeneDecksing
|
Genomic Variants
for C20orf112 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for C20orf112 (31030862 - 31172876 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C20orf112
1 Indel: 59021 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C20orf112 |
|
Disorders
/ Diseases
for C20orf112 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C20orf112 for disorders About GeneDecksing
3  diseases for C20orf112: About MalaCardsacute myeloid leukemia myeloid leukemia leukemia
Export disorders for C20orf112 gene to outside databases
|
Publications
for C20orf112 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C20orf112 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with C20orf112) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2, 3 Deloukas P....Rogers J. (2001)
- CBFA2T2 and C20orf112: two novel fusion partners of R UNX1 in acute myeloid leukemia. (PubMed id 20520637)1, 3 Guastadisegni M.C....Storlazzi C.T. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)1, 3 Beausoleil S.A....Gygi S.P. (2004)
- Dominant-negative mechanism of leukemogenic PAX5 fusio ns. (PubMed id 21765475)1 Kawamata N....Koeffler H.P. (2012)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for C20orf112 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C20orf112 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C20orf112 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C20orf112 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C20orf112 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for C20orf112 gene:
Search GeneIP for patents involving C20orf112
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C20orf112 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C20orf112 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C20orf112 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C20orf112 | | | OriGene Protein Over-expression Lysate for C20orf112 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C20orf112 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf112 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C20orf112 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | C20orf112 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C20orf112 |
|  |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C20orf112 |
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