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Aliases for C1orf95 Gene

Aliases for C1orf95 Gene

  • Chromosome 1 Open Reading Frame 95 2 3

External Ids for C1orf95 Gene

Previous GeneCards Identifiers for C1orf95 Gene

  • GC01U901140
  • GC01P224803
  • GC01P226736
  • GC01P197253

Summaries for C1orf95 Gene

GeneCards Summary for C1orf95 Gene

C1orf95 (Chromosome 1 Open Reading Frame 95) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf95 Gene

Genomics for C1orf95 Gene

Regulatory Elements for C1orf95 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C1orf95 Gene

226,548,248 bp from pter
226,609,214 bp from pter
60,967 bases
Plus strand

Genomic View for C1orf95 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C1orf95 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf95 Gene

Proteins for C1orf95 Gene

  • Protein details for C1orf95 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein stum homolog
    Protein Accession:
    Secondary Accessions:
    • A6NGL2

    Protein attributes for C1orf95 Gene

    141 amino acids
    Molecular mass:
    15007 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C1orf95 Gene

Proteomics data for C1orf95 Gene at MOPED

Post-translational modifications for C1orf95 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf95 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf95 Gene

Domains & Families for C1orf95 Gene

Protein Domains for C1orf95 Gene


Suggested Antigen Peptide Sequences for C1orf95 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPEC3 family. Stum subfamily.
  • Belongs to the SPEC3 family. Stum subfamily.
genes like me logo Genes that share domains with C1orf95: view

No data available for Gene Families for C1orf95 Gene

Function for C1orf95 Gene

Phenotypes for C1orf95 Gene

genes like me logo Genes that share phenotypes with C1orf95: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf95

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C1orf95 Gene

Localization for C1orf95 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C1orf95 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for C1orf95 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C1orf95: view

No data available for Subcellular locations from COMPARTMENTS for C1orf95 Gene

Pathways & Interactions for C1orf95 Gene

SuperPathways for C1orf95 Gene

No Data Available

Interacting Proteins for C1orf95 Gene

Gene Ontology (GO) - Biological Process for C1orf95 Gene


No data available for Pathways by source and SIGNOR curated interactions for C1orf95 Gene

Drugs & Compounds for C1orf95 Gene

No Compound Related Data Available

Transcripts for C1orf95 Gene

mRNA/cDNA for C1orf95 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf95 Gene

Chromosome 1 open reading frame 95:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C1orf95

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf95 Gene

No ASD Table

Relevant External Links for C1orf95 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C1orf95 Gene

mRNA expression in normal human tissues for C1orf95 Gene

mRNA differential expression in normal tissues according to GTEx for C1orf95 Gene

This gene is overexpressed in Brain - Amygdala (x6.9), Brain - Anterior cingulate cortex (BA24) (x5.7), and Brain - Hippocampus (x5.2).

Protein differential expression in normal tissues from HIPED for C1orf95 Gene

This gene is overexpressed in Fetal Brain (16.3), Platelet (11.8), Rectum (11.2), Prostate (7.5), Urinary Bladder (7.2), and Frontal cortex (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C1orf95 Gene

SOURCE GeneReport for Unigene cluster for C1orf95 Gene Hs.116827

genes like me logo Genes that share expression patterns with C1orf95: view

Protein tissue co-expression partners for C1orf95 Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for C1orf95 Gene

Orthologs for C1orf95 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf95 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C16H1orf95 35
  • 95 (n)
  • 99.29 (a)
MGC151592 36
  • 99 (a)
(Canis familiaris)
Mammalia C7H1orf95 35
  • 93.29 (n)
  • 94.24 (a)
C1orf95 36
  • 95 (a)
(Mus musculus)
Mammalia 6330403A02Rik 35
  • 91.49 (n)
  • 97.87 (a)
6330403A02Rik 16
6330403A02Rik 36
  • 98 (a)
(Pan troglodytes)
Mammalia C1H1orf95 35
  • 99.76 (n)
  • 100 (a)
C1orf95 36
  • 100 (a)
(Rattus norvegicus)
Mammalia LOC689499 35
  • 90.78 (n)
  • 97.16 (a)
(Monodelphis domestica)
Mammalia C1orf95 36
  • 78 (a)
(Gallus gallus)
Aves C1ORF95 35
  • 84.31 (n)
  • 89.71 (a)
C1ORF95 36
  • 84 (a)
(Anolis carolinensis)
Reptilia C1orf95 36
  • 69 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490899 35
  • 83.65 (n)
  • 97.17 (a)
(Danio rerio)
Actinopterygii si:dkeyp-59a8.4 35
  • 81.41 (n)
  • 92.31 (a)
C20H1orf95 36
  • 83 (a)
Species with no ortholog for C1orf95:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C1orf95 Gene

Gene Tree for C1orf95 (if available)
Gene Tree for C1orf95 (if available)

Paralogs for C1orf95 Gene

No data available for Paralogs for C1orf95 Gene

Variants for C1orf95 Gene

Sequence variations from dbSNP and Humsavar for C1orf95 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs478406 -- 226,578,840(+) CCTCA(C/T)ACCCC intron-variant
rs479225 -- 226,578,911(+) ATTAG(A/G)GACTT intron-variant
rs483048 -- 226,579,326(+) TGCCA(A/G)CTCCC intron-variant
rs493608 -- 226,604,142(+) GGGCC(A/G)CCCCC utr-variant-3-prime
rs496083 -- 226,591,910(+) CGAGT(C/T)AGGAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf95 Gene

Variant ID Type Subtype PubMed ID
nsv832781 CNV Gain 17160897
nsv470779 CNV Loss 18288195
nsv873234 CNV Loss 21882294
nsv522446 CNV Loss 19592680
nsv4755 CNV Insertion 18451855

Variation tolerance for C1orf95 Gene

Residual Variation Intolerance Score: 40.39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.89; 18.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf95 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf95 Gene

Disorders for C1orf95 Gene

Relevant External Links for C1orf95

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C1orf95: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf95 Gene

Publications for C1orf95 Gene

  1. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 67
  2. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 67
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 67
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67

Products for C1orf95 Gene

Sources for C1orf95 Gene

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