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Aliases for C1orf94 Gene

Aliases for C1orf94 Gene

  • Chromosome 1 Open Reading Frame 94 2 3 5

External Ids for C1orf94 Gene

Previous GeneCards Identifiers for C1orf94 Gene

  • GC01P034303
  • GC01P034405
  • GC01P034632
  • GC01P032749

Summaries for C1orf94 Gene

GeneCards Summary for C1orf94 Gene

C1orf94 (Chromosome 1 Open Reading Frame 94) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C1orf94 Gene

Genomics for C1orf94 Gene

Regulatory Elements for C1orf94 Gene

Enhancers for C1orf94 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C1orf94 on UCSC Golden Path with GeneCards custom track

Promoters for C1orf94 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for C1orf94 Gene

Chromosome:
1
Start:
34,166,883 bp from pter
End:
34,219,131 bp from pter
Size:
52,249 bases
Orientation:
Plus strand

Genomic View for C1orf94 Gene

Genes around C1orf94 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C1orf94 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C1orf94 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C1orf94 Gene

Proteins for C1orf94 Gene

  • Protein details for C1orf94 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P1W5-CA094_HUMAN
    Recommended name:
    Uncharacterized protein C1orf94
    Protein Accession:
    Q6P1W5
    Secondary Accessions:
    • B3KVT1
    • D3DPR3
    • E9PJ76
    • Q96IC8

    Protein attributes for C1orf94 Gene

    Size:
    598 amino acids
    Molecular mass:
    65353 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C1orf94 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C1orf94 Gene

Post-translational modifications for C1orf94 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C1orf94 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C1orf94 Gene

Domains & Families for C1orf94 Gene

Protein Domains for C1orf94 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C1orf94: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C1orf94 Gene

Function for C1orf94 Gene

Gene Ontology (GO) - Molecular Function for C1orf94 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with C1orf94: view
genes like me logo Genes that share phenotypes with C1orf94: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C1orf94 Gene

Localization for C1orf94 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C1orf94 Gene COMPARTMENTS Subcellular localization image for C1orf94 gene
Compartment Confidence
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C1orf94 Gene

Pathways & Interactions for C1orf94 Gene

SuperPathways for C1orf94 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C1orf94 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C1orf94 Gene

Drugs & Compounds for C1orf94 Gene

No Compound Related Data Available

Transcripts for C1orf94 Gene

mRNA/cDNA for C1orf94 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(21) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C1orf94 Gene

Chromosome 1 open reading frame 94:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C1orf94 Gene

No ASD Table

Relevant External Links for C1orf94 Gene

GeneLoc Exon Structure for
C1orf94
ECgene alternative splicing isoforms for
C1orf94

Expression for C1orf94 Gene

mRNA expression in normal human tissues for C1orf94 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C1orf94 Gene

This gene is overexpressed in Testis (x39.4).

Protein differential expression in normal tissues from HIPED for C1orf94 Gene

This gene is overexpressed in Plasma (37.1), Platelet (21.4), and Heart (10.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for C1orf94 Gene



Protein tissue co-expression partners for C1orf94 Gene

NURSA nuclear receptor signaling pathways regulating expression of C1orf94 Gene:

C1orf94

SOURCE GeneReport for Unigene cluster for C1orf94 Gene:

Hs.194610
genes like me logo Genes that share expression patterns with C1orf94: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for C1orf94 Gene

Orthologs for C1orf94 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C1orf94 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C3H1orf94 34
  • 83.33 (n)
  • 77.42 (a)
C1orf94 35
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C15H1orf94 34
  • 79.59 (n)
  • 71.65 (a)
C1orf94 35
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia CK137956 34
  • 80.33 (n)
  • 73.02 (a)
CK137956 16
CK137956 35
  • 73 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf94 34
  • 97.28 (n)
  • 95.83 (a)
C1orf94 35
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC682102 34
  • 80.12 (n)
  • 73.65 (a)
oppossum
(Monodelphis domestica)
Mammalia C1orf94 35
  • 63 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf94 35
  • 45 (a)
OneToOne
chicken
(Gallus gallus)
Aves C1ORF94 34
  • 58.62 (n)
  • 45.14 (a)
C1orf94 35
  • 47 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf94 35
  • 39 (a)
OneToOne
Species where no ortholog for C1orf94 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C1orf94 Gene

ENSEMBL:
Gene Tree for C1orf94 (if available)
TreeFam:
Gene Tree for C1orf94 (if available)

Paralogs for C1orf94 Gene

No data available for Paralogs for C1orf94 Gene

Variants for C1orf94 Gene

Sequence variations from dbSNP and Humsavar for C1orf94 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1382602 - 34,197,607(-) GACTT(C/G)CAAGT reference, missense
rs1414474 - 34,197,810(-) AGCTT(C/G)TCAGG reference, missense
rs17556981 - 34,202,125(+) CGAAG(C/T)ACACA reference, missense
rs182434 -- 34,175,195(-) AAAAA(A/T)AAAAT intron-variant, upstream-variant-2KB
rs184171 -- 34,171,505(-) AAACA(G/T)TACTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C1orf94 Gene

Variant ID Type Subtype PubMed ID
esv3446717 CNV insertion 20981092
esv3577807 CNV loss 25503493
nsv1076370 CNV deletion 25765185
nsv470709 CNV gain 18288195
nsv475181 CNV novel sequence insertion 20440878
nsv545964 CNV gain 21841781
nsv545966 CNV loss 21841781
nsv834646 CNV gain 17160897
nsv834657 CNV gain 17160897
nsv834669 CNV gain 17160897

Variation tolerance for C1orf94 Gene

Residual Variation Intolerance Score: 70.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.08; 80.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C1orf94 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C1orf94

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C1orf94 Gene

Disorders for C1orf94 Gene

Relevant External Links for C1orf94

Genetic Association Database (GAD)
C1orf94
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C1orf94

No disorders were found for C1orf94 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C1orf94 Gene

Publications for C1orf94 Gene

  1. Open reading frames associated with cancer in the dark matter of the human genome. (PMID: 25048349) Delgado A.P. … Narayanan R. (Cancer Genomics Proteomics 2014) 2 3 65
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  3. SR protein kinases promote splicing of nonconsensus introns. (PMID: 26167880) Lipp J.J. … Guthrie C. (Nat. Struct. Mol. Biol. 2015) 3 65
  4. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3 65
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 65

Products for C1orf94 Gene

Sources for C1orf94 Gene

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