Aliases for C1orf86 Gene
External Ids for C1orf86 Gene
GeneCards Summary for C1orf86 Gene
C1orf86 (Chromosome 1 Open Reading Frame 86) is a Protein Coding gene. GO annotations related to this gene include ubiquitin binding and K63-linked polyubiquitin binding.
UniProtKB/Swiss-Prot for C1orf86 Gene
Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds Lys-63-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.